<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11007
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MKESLSLPLRPFVQRSVTEPDSLPIRIAQINSQRGSFRNVTEQSLQAEIDAQQATAAAGLEAEETEEAESQEAKSTDRLEQLFKSRAEIVDFVAQAHAEANYALDLVSLLISKYTPRQAEISMSPYLKQKAPLGSLGIDIIKTQEKTETTQKDIVDLSRGWKLETFDFAANKLLQAAFRLEQEVAAETKYWADVLSIKEKGWKICRLPRERQTLGVQCGFLEATPTLRDRGLAALRRGHGGDLILDRGLQPSQPRSLRVRVQQHNQIVGSSKLISLELVPGDNSIEHCIRLARDVLYEEELFHELNREARTLLQHGIESKGNLIQFQASDNQQILIDMVSLDEYNISDFDKQEHAEDALAEAVAQSLRLLLSHAHRKKYRRRARIPPPVTLKRRPNPEYSLLQPVVSYLQHKSALQWLKSVLGTITRTLQLAGLKCKHDVSPLIFVRLPPVNKTIPYPSEPDTLPFVERLVDTFLTPLESIVTGTLLTPTSSFKIRIITNISPNGYGTEFEIATNMTSGSRTKSSSSRFGLRDDLQQLLLHLYTTDLVYLIPALTLGTSTESSPLPTSSQQKQEQGQERLQPEQTHFNTPVQPHTSHPTPWTPTSPENGELVASFPTQRRSKKLNIDLRPERLTILCQWLGAGLADLGEDLESVAGEGNVIYSWSDDGGNERKTLQSIMCLLSQWETKPEL |
Length | 691 |
Position | Head |
Organism | Blastomyces percursus |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Onygenales> Ajellomycetaceae> Blastomyces.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.435 |
Instability index | 52.35 |
Isoelectric point | 6.09 |
Molecular weight | 77603.12 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP11007
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 125.70| 36| 36| 558| 593| 1
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522- 544 (30.26/13.33) ........TKSS....S...........SRFGL...RDDLQQLLLHLYT
552- 589 (58.82/32.67) PALTlgTSTESSPLPTS...........SQQKQEQGQERLQPEQTHFNT
590- 632 (36.62/17.64) PVQP.hTSHPTPWTPTSpengelvasfpTQRRSKKLNIDLRPER.....
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 35.81| 11| 38| 153| 163| 2
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153- 163 (20.29/14.11) DIVDLS.RGWKL
193- 204 (15.51/ 9.05) DVLSIKeKGWKI
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 45.89| 14| 16| 217| 232| 4
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217- 232 (21.51/19.80) QCGflEATPTLRDRGL
236- 249 (24.38/14.54) RRG..HGGDLILDRGL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 103.02| 33| 36| 31| 63| 5
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31- 63 (51.50/35.85) NSQRGSFRNVTEQSLQAEIDAQQATAAAGLEAE
69- 101 (51.52/35.87) ESQEAKSTDRLEQLFKSRAEIVDFVAQAHAEAN
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