<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10911

Description Mediator of rna polymerase ii transcription subunit 33a
SequenceMKTETVHSIFDTVTELTKSAQEKNTDPLIWAMQLSSSLNSAGVSMPSVAVGEILVNHICWSNNVPIAWKFLEKALTVRIVPPLFVLALLSTRVIPTRRSCPMAYRLYMELLKRYAFSLPSQINGPNYQKIMESINDTLQLSQIFELQGSESGKHVVGYVFMVVWQLLDASLDDEGLLELTAEKKSRWPVATQEMEISNRDGFAGKRVEHREGLCRMNTVLAIEIIGELFGDKLISMILYLARKNMPTHWDSFMQHLQLLVSNSAALRNSKNISPEALVLLISKNLGVLSRECKTSSRQFFHAVMASGSLAFSASRRDAASTSVLWLPIDLFLEDTMDGLQVAATSSADTLTGLVKALQATNRTTWQDTFFGLWISALRLVNRERDSSEGPVPRLDTFLCLLLSITPLAITNIIEEENDSTSSDQRKESTEKRCQALVSSLQQLHDYEALLTPPLPAILLANQAAVKAMMFLSGLSMGSEYFDGMKLNGMPVNCAGNLWHLIVEACIARNILDTSAYLWPGYVKGQCNQVPRSISGPLLGWSSLMKGSLLTPPMVSALVSTPASSLAEIEKIYEIAVNGSDEEKISAATILCGASLARGWNIQEHTVLFITRLLSPCVPSDYCGTESHLISYAPVLNVLLIGISSIDCIQIFSLHGLVPQLAGVLMPICEAFGSCAPNVSWTLMSEKVNSHAVFSNAFTLLLKLWRFDQPPLEHVTRDVPVGSHLTPEYLLLVRNSQLACSEDLLKGQSKSKQLSRTPCRLPEEPIFMDSFPKLKCWYRQNQACIASPLSGLVPGTPVHQIVEALLNFMFRKINSAGQSLTPTTSSGSNSSGSGNEDISPHLKLPAWDILEAVPFVLDAALTACGHGRLSPRELATGLKDLADFLPASLATIASYFSAEVTRGLWKPAFMNGTDWPSPAANLATVEQQIKKILAATGVDVPSLSVGGNSPAILPLPLAVLASLTITYKLERGTDRFLNLVGTALSNLATSCPWPCMPVIAALWAQKVRRWSDFLVFSASRTVFHHSSDAVGQLLRVCFTATLGLGTSSIESNGGVGSLLGHGFGSHFSGGISPVAPGILYLRVHRVVRNVMFMAEEVVTLLMYFVRIIADGGFPAEELEKLKKTRNPMSSLSCHNMESGFPAFCQVSLASAMTRVKLAASLGASLVWITGGLSLVQALLKETLPSWFISAHRSEPNGGVSEGMVSRLRGYALAYFALLSGTFAWGVDSLSPASKWRPSILGAHLEFLASALDGKISLGCNKATWRAYVSGFIGLMVGCTPSWLLEVDVDVLKRLSKGLKRLNEEVLALALLEASGVGAMGIAAEMIIEGGLNFC
Length1333
PositionTail
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.08
Grand average of hydropathy0.206
Instability index45.54
Isoelectric point6.62
Molecular weight144846.24
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
phenylpropanoid metabolic process	GO:0009698	IEA:EnsemblPlants
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10911
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.88|      40|      93|    1183|    1225|       1
---------------------------------------------------------------------------
 1183- 1225 (61.23/48.43)	PSWFISAHrSEPNGGVSEGMvSRLRGYALAyFALL..SGTFAWGV
 1279- 1320 (58.65/33.22)	PSWLLEVD.VDVLKRLSKGL.KRLNEEVLA.LALLeaSGVGAMGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     275.29|      91|      99|     493|     590|       4
---------------------------------------------------------------------------
  477-  536 (68.47/46.02)	..........................................GSeyfDGMKLNGMPVN.....CAGNL...WHLIVEaciaRNILDTSAYLWPGYVKGQCNQVPRSIS.GP
  537-  633 (137.95/92.84)	LLGWSSLMKGSLLTppmVSALVSTPASSLAEI.EKIYEIAVNGS...DEEKISAATIL.....CGASLargWN.IQE....HTVLFITRLLSPCVPSDYCGTESHLISyAP
  639-  706 (68.86/37.03)	LIGISSIDCIQIFS...LHGLVPQLAGVLMPIcEAFGSCAPNVSwtlMSEKVNSHAVFsnaftLLLKL...WRF.....................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     397.30|     109|     516|     246|     396|       5
---------------------------------------------------------------------------
  175-  218 (35.47/45.48)	....................................................................GLLE.LTAEKKSRWPVATQEMEISN.RdgFAGKRVEHREG.LCRMNT
  286-  396 (177.72/87.62)	GVLS.RECKTSSRQFfhAVMASGSLAFSASR.RDAASTSVLWLPIDLFLEDTMDGLQVAATSSADTLTGLVKALQATNRTTWQDTFFGLWISALR..LVNRERDSSEGPVPRLDT
  866-  919 (65.98/21.11)	GRLSpRELATGLKDL..ADFLPASLATIASY.FSAEVTRGLWKPA..FMNGT.DWPSPAA.......................................................
  952- 1034 (118.14/50.21)	....................LPLPLAVLASLtITYKLERGT....DRFLNLVGTALSNLATSCPWPCMPVIAALWAQKVRRWSD..F.LVFSASR..TVFHHSSDAVGQLLR...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.22|      22|     277|     786|     808|       6
---------------------------------------------------------------------------
  786-  808 (36.53/29.53)	SPLS.GLVPGTP......VHQIVEALLnFM
 1064- 1092 (31.69/19.72)	SHFSgGISPVAPgilylrVHRVVRNVM.FM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.69|      33|      35|      38|      72|       9
---------------------------------------------------------------------------
   24-   61 (43.91/32.75)	NTDPLIWAMqLSssLNSAGVsmPSVAVGEILVNHICWS
   62-   96 (49.78/30.96)	NNVPIAWKF.LEkaLTVRIV..PPLFVLALLSTRVIPT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10911 with Med33 domain of Kingdom Viridiplantae
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