<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10888

Description Mediator of rna polymerase ii transcription subunit 15a
SequenceMDGKNWKAQSRAQARAQARARARARGGGEGTALSAAPAGGLRASVDPTAQTRYANGADWQEEVYQKIKSMKEMYLPKLNDLYHKVASEVQQCPQHEKIEKFKVFKLKLEYFVLLLQLNKHDIQLYDKEKLLSVEKHINFFLKSNNPPQPDSSLLQGQLPQPPVYTSQTPMMGSGWQDIASHFYRLDDSSYGLGSKQNSFGIATSGFDRLGSSSGANLVEERLGMVEERLEKIEAHSKKAEALLTDINKKMNYPVKIRYVKVSRDIRCPAKYMNCHFRPKRKNRSGSRASIDD
Length292
PositionTail
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.08
Grand average of hydropathy-0.736
Instability index44.48
Isoelectric point9.61
Molecular weight33026.25
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP10888
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.22|      15|     110|     128|     142|       1
---------------------------------------------------------------------------
  128-  142 (24.92/20.27)	EKLL.SVEKHINFFLK
  240-  255 (20.30/15.18)	EALLtDINKKMNYPVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.12|      17|      21|     172|     191|       2
---------------------------------------------------------------------------
  174-  191 (31.08/30.90)	GWQD....IA.SHFYRLDDSSyG
  193-  214 (22.04/ 8.75)	GSKQnsfgIAtSGFDRLGSSS.G
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP10888 with Med15 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MDGKNWKAQSRAQARAQARARARARGGGEGTAL
1
33

Molecular Recognition Features

MoRF SequenceStartStop
1) MDGKNWKAQSRAQARAQARARARARG
1
26