<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10882

Description Pre-mrna-processing protein 40a
SequenceMASNPPPSGPQPHWPPSVGSTPPQGFGPSFPMQFRPAVSTQQGQPFASSFSASPQYRPVGQTSNAGMPPGHHGQIPQFSQPMQQFPPRPSQPGHGILSSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSYTVQSSSQMHVPPFPPGGQPWLSSGSQTTPVAAPNLLTSQQLSAIAPSVPAGTASQQNASDWQEYEAADGRRYYYNKITKQSSWEKPLELMTPLERADASTVWKEFTTADGRKYYYNKETKQSKWTIPEELKLARELAEKSAGQVVQTGASTISGVQVTAAVTSTEQPSAVTPVSSTPSSTVSGVASSPVPVTSAVSDHASPLVVSGSSAIPAVTPAMPSSSGVSSPAVSGSTGSAALANASQTQMSGFENLSPQVASSLSGASIQDIEEAKKGMAVAGKVNVVPAEEKTTEEEPFLYATKQEAKNAFKALLEFANVESDWTWEQTMRVIINDKRYGALKTLGERKQAFNEYLMQRKKQEAEERRHRQRKAKEEFTKMLEESKELISSTRWSKAVTMFEDDERFKAVEREADREDLFRNYLVDLQKKERAKAQEEYRQNRLEYRQFLETCGFIKVDTQWRKVQDLLEDDERCLRLEKIDRLDIFQEYIRDLEKEDEEQRKLQKEKLRRTERKNRDAFRKMMEEQIAAGTLTAKTSWRDYCQMVKESVAYQAVASNTSGSTPKDLFEDVVEELEKQYHEDKIRIKDVVKSEKITISSTWTFEDFKAAILEGIGSPSIHDVNLQLIFEDLIERAKEKEEKETKKRQRLAKDFTDKLSTIKEITASSSWEECKELVEDSSEFRAIGEETISRAVFEEYVALLQEKAKEKERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKEREKEKERGKERSTKDEADSESMDVTDNYEPKEERKREKDKERKHRKRHHISNDEVTSDKDEKEEPERDKERKHRKRHHSSNDEVASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGYEELEDGELGEDGES
Length1033
PositionUnknown
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-1.093
Instability index61.18
Isoelectric point6.22
Molecular weight117312.91
Publications









Function






Annotated function


GO - Cellular Component
cytosol	GO:0005829	IEA:EnsemblPlants
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10882
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     203.51|      31|      32|     917|     947|       1
---------------------------------------------------------------------------
  851-  877 (31.77/10.30)	E...KAKKEKEKEEKEKRKDKERREKEREK....
  900-  933 (49.03/19.59)	EsmdVTDNYEPKEERKREKDKERKHRKRHHISND
  934-  962 (53.18/21.82)	E...VTSDKDEKEEPERDK..ERKHRKRHHSSND
  963-  983 (33.70/11.34)	E...VASDKDEKEESKRS....RR.....H.SSD
  984- 1013 (35.84/12.49)	R...KKS.KKLAHSPESDGESRHKRHRRDHRDGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.89|      33|      38|     196|     233|       2
---------------------------------------------------------------------------
  196-  228 (68.40/37.91)	NASD.WQEYEAADGRRYYYNKITKQSSWEKPLEL
  236-  269 (61.49/40.84)	DASTvWKEFTTADGRKYYYNKETKQSKWTIPEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     190.05|      21|      21|      16|      36|       3
---------------------------------------------------------------------------
   16-   36 (44.90/23.77)	PSVGST.P.P..QGFG..PSF...PMQFR.P
   40-   58 (25.39/10.29)	TQQG........QPFA..SSFsasP.QYR.P
   62-   86 (28.66/12.55)	TSNAGM.P.P..GHHGqiPQF.sqPMQQF.P
   87-  103 (20.85/ 7.15)	PR.PSQ.P.G..HGIL..SSQ...AIQ....
  105-  126 (20.13/ 6.65)	PFIQSSmPqP..QQVI..P.....PLNSHmP
  127-  150 (22.11/ 8.02)	GVSGAG.N.P....FS..SSY...TVQMHvP
  151-  168 (28.03/12.11)	PF.....P.PggQPWL..SSG...S.QTT.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     488.08|      65|      65|     507|     571|       4
---------------------------------------------------------------------------
  440-  503 (85.00/64.50)	QEAKNAFKALLEF...A.NVESDWTWEQTMRVIINDKRYGALKTL...GERKQAFNEYLMQRK.....KQ...EAEERR
  507-  571 (103.28/80.35)	RKAKEEFTKMLEE...SKELISSTRWSKAVTMFEDDERFKAVERE...ADREDLFRNYLVDLQ.....KK...ERAKAQ
  575-  640 (88.50/67.54)	RQNRLEYRQFLET...CGFIKVDTQWRKVQDLLEDDERCLRLEK....IDRLDIFQEYIRDLE.....KE.deEQRKLQ
  649-  722 (75.03/55.86)	RKNRDAFRKMMEEqiaAGTLTAKTSWRDYCQMVKESVAYQAVASNtsgSTPKDLFEDVVEELE.....KQyheDKIRIK
  723-  773 (56.89/40.14)	DVVKSE...........KITISST.WT.....FED...FKAAILE...GIGSPSIHD..VNLQlifedLI...ERAKEK
  783-  842 (79.38/59.63)	RLAK.DFTDKLST...IKEITASSSWEECKELVEDSSEFRAIGEE...TISRAVFEEYVALLQ..........EKAK..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.95|      25|      26|     343|     367|       5
---------------------------------------------------------------------------
  343-  367 (46.36/28.25)	VSGSS..AIPAVTPAMPSS.SGVS..S.PAV
  370-  394 (21.73/ 9.26)	STGSA..AL...ANASQTQmSGFEnlS.PQV
  398-  424 (18.87/ 7.05)	LSGASiqDIEEAKKGMAVA.GKVN..VvPA.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.11|      24|      32|     283|     306|       6
---------------------------------------------------------------------------
  283-  306 (41.57/30.91)	VVQTGASTISG.....VQVTAAVTSTEQP
  312-  340 (36.54/26.18)	VSSTPSSTVSGvasspVPVTSAVSDHASP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10882 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKEKERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKEREKEKERGKERSTKDEADSESMDVTDNYEPKEERKREKDKERKHRKRHHISNDEVTSDKDEKEEPERDKERKHRKRHHSSNDEVASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGYEELEDGELGEDGES
2) MASNPPPSGPQPHWPPSVGSTPPQGFGPSFPMQFRPAVSTQQGQPFASSFSASPQYRPVGQTSNAGMPPGHHGQIPQFSQPMQQFPPRPSQPGHGILSSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSYTVQSSSQMHVPPFPPGGQPWLSSGSQTTPVAAPNLLTSQ
3) VQVTAAVTSTEQPSAVTPVSSTPSSTVSGVASSPVPVT
841
1
294
1033
178
331










Molecular Recognition Features






MoRF SequenceStartStop




1) GYEELEDGEL
2) KKSKKLAHS
3) RHKRHRRDHR
1018
985
1001
1027
993
1010