<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10881

Description Mediator of rna polymerase ii transcription subunit 33a
SequenceMEVSMDCSLWDSVLELTKVSQEKGGDPLVWAIQVSSCLSSAGVSLPSLELANFLVSHICWENNLPIVWKFLEKALVLKIVSPIIVFPLLSSRVIQNRRLRPAAFRLYMELLRRHIFTLKIHVNMQSYKKIVSFLDSVLYLTEIFGMHADEPGVLVVEIIFSIVWQLLDASLDDEGLLQLTPEKKSRWPTKPEDMEIDGCITDMERNEHKERLKNLNTLLAIELIAQFLQNKVTARILYLARQNMPVHWGAFVQRIQLLAGNSSALQSSSVISPEALLQLASDAHNLIKTNSLQERYVRSTLRSLATCAGLCFGSSRSSLWLPLDLFLEDAMDGSQVNATSAIEIITDLVKSLQAINATTWHETFLGLWMAALRLVQRERDPIEGPMPRLDTRLCMLFSIITLVVADLIEEEESEACDEIESSIGRHMKKQVAGTRRRDIVSCLQSLGDYQSLLTPPQAITTAANQAAAKAMMFRSGINTNSSYFECINLKDLPINCSGNLYHLIVEACIARNLLDTSAYFWPGYVNGRMNQLPHSMPTQVPGWSSFMKGAPLTQAMINALVSAPASSLAELEKIFEMAVKGADDEKIAAATILCGASLIHGWNIQEHAVNFITRLLSPPVPTDYSGKDSHLIGYAPTLNVLLVGIAPVDCVQIFSLHGMVPQLAASLMTICEVFGSCVPNISWTLTTGEDISVHAVFSNAFALLLKLWRFNHPPIEYRVGDVPPVGCQLTPEYLLLMRNSHLVSSGDMLKDPNRRRLAAVASSSSPNPIFVDSFPKLRVWYRQHLACIASTLSGLVNGTLVCQTVDLLLNMMFKKINGGSQSLISITSGSSSSSGTGSEDTSPRPKLPAWDILEAVPFVVDAALTACAHGRLSPRELCTGLKDLADFLPASLATIVSYFSAEVTRGVWKPVFMNGTDWPSPAANLSNVEEQIKKILAATGVDVPSLAAGGSSPAILPLPLAAFVSLTITYKLDKASQRFLNLAGPALESLAAGCPWPCMPIVASLWTQKAKRWSDFLVFSASRTVFLNNNHAVIQLLKSCFMTTLGLNSSSISSNGGIGALLGHGFGSHFYGGISPVAPGILYLRVYRSIRDIMFLREEIVSLLMQSISDIAHSDLPRQRLDKLKIPKNGKKFGNVSLAKTMTRVKLAALLGASLLWLSGGSGLVQSLIKETLPSWFLSVHSSNQGGEGGLVPMLKGYALAYFAVLCGAFASGVDSLSMASKRRPKIIGRHVEFIASVLDGKISLGCDPATWHAYVSGFVSLMVGCTPTWVFEVDAELLKRLSKGLRQWHEEDLALALLSIGGVGTMGSAAELIMEVSS
Length1319
PositionTail
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy0.222
Instability index48.04
Isoelectric point6.85
Molecular weight143938.61
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10881
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.11|      43|     131|     493|     538|       1
---------------------------------------------------------------------------
  493-  538 (77.31/64.03)	PINCSGNLYHLIVEACIARNLL......DTSAYFWpgyVNGRMNQLPHSMPT
  621-  669 (71.80/49.43)	PTDYSGKDSHLIGYAPTLNVLLvgiapvDCVQIFS...LHGMVPQLAASLMT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.37|      27|     130|       8|      34|       2
---------------------------------------------------------------------------
    8-   34 (46.97/26.46)	SLWD.SVLELTKVSQEKGGDPLVWAIQV
  132-  158 (44.51/24.71)	SFLD.SVLYLTEIFGMHADEPGVLVVEI
  170-  188 (20.88/ 7.93)	SLDDeGLLQLT..PEKKSRWP.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.69|      36|     132|    1026|    1081|       4
---------------------------------------------------------------------------
 1045- 1081 (59.40/56.50)	LGLNSSSISSNGGIGALLgHGFGSHFYGGI.SPVAPGI
 1178- 1214 (57.30/21.49)	LSVHSSNQGGEGGLVPML.KGYALAYFAVLcGAFASGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     147.70|      42|     637|     281|     326|       5
---------------------------------------------------------------------------
  285-  326 (78.02/48.10)	NLIKTNSLQ...ERYVR...STLRSLAT.CAGLCFGSSRSSLWLPLDLF
  945-  963 (24.45/ 7.31)	........................SLA...AG...GSSPAILPLPLAAF
  965- 1006 (45.23/18.21)	SLTITYKLDkasQRFLNlagPALESLAAgCPWPCM.PIVASLW......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.91|      34|     927|     331|     367|       6
---------------------------------------------------------------------------
  331-  367 (48.93/48.78)	MDGsqVNATSAIEIITDLVKSLQAiNATTWHETFLGL
 1263- 1296 (61.98/47.66)	MVG..CTPTWVFEVDAELLKRLSK.GLRQWHEEDLAL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10881 with Med33 domain of Kingdom Viridiplantae
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