<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10877
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MENLFNLNHKLVFNKKEDAFGRFGTICKFSSNNLFAYSSEIDIITAEKGFFVYMFDFNLPWYTYKVASFKYPIVNIEWDQSGYFILVADNYGNISVYTMENNLISEWIEVCSVSFPSENIIATKFFNNGIRIAKYQQDKRDQVLYSDKYYRPKFQPTVRKFGGVSDFGCVCVTSTGLIGAFSIDLNFTGNDNNKKTNKTSRNLGQTRGLCTLADISFKNGQFQIAVVNSAQKNSLVQCYRVQIEKIDEDNLVIVSKSLPSFFVNESMAYKEAVDAKIHRLKWMSQEDSDSLIISSNHSSGSIVEIWTLKEEQTLIHKIFQTTKNEAYKTLGWSNQQNYKHSRKVLDVITTKVQFTANFYIFIAYQDSSIHCLNREGLKRVAINNIHLTASALEHQTKQIKITSKITSLDISYMGHILIATDSIGQVSCYRINFDHIMNNLVHAANLFEFCMISGLDTLDSQLLLKPLSINDLVDKLTDNFNRQPNHVTQFYYLKFLTMKINLYRMCSFGQSKAHDLVCLLNLISISTAFKSLLRPADLMTMKNGPAENLAMNLSESSLPDVDKVLVNLEAKDFTVEPSTLQSLQQLIQFVADLALNILSKLPEGRTFLNTNKTTGDLSDFTALNSIRELLVMIRIWGLLKPQCLPVFSRSADNLDILATLFRLLTKLAPKPTDPDDQLLDECCLLPNQVLIPQIQLNTPRISLSSPLLVNAPLPLHLEYNVECDLLDFIPELHYVEGCLMNNNIMDSIRYIHLGKSSANLRRCSRCGSYSSLKSVARTAAMKGWESRWNTCKCGGLWKLEKC |
Length | 802 |
Position | Tail |
Organism | Clunio marinus |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Diptera> Nematocera> Chironomoidea> Chironomidae>
Clunio.
|
Aromaticity | 0.10 |
Grand average of hydropathy | -0.111 |
Instability index | 38.45 |
Isoelectric point | 8.08 |
Molecular weight | 91127.83 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP10877
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 99.82| 32| 41| 247| 286| 1
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247- 280 (45.54/49.47) DEDNLvIVSKSLPSFFVNESMAYKEAvDAKIHRL
287- 318 (54.28/31.56) DSDSL.IISSNHSSGSIVEIWTLKEE.QTLIHKI
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 89.96| 33| 41| 548| 587| 2
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548- 587 (41.00/40.93) NLAMNLsESSLPD......VDKVLVNLeaKDFTvepsTLQSLQQLI
592- 630 (48.96/27.63) DLALNI.LSKLPEgrtflnTNKTTGDL..SDFT....ALNSIRELL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 80.23| 23| 41| 52| 76| 3
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52- 76 (40.90/27.29) VYMFDFNL..PWytYKVASFKYPIVNI
96- 120 (39.33/20.17) VYTMENNLisEW..IEVCSVSFPSENI
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 110.24| 39| 46| 364| 409| 4
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364- 409 (50.54/53.13) Y.......QDS..SIHCLnREGLKRVAINNIHlTASALEhqtkqIKITSKITSLD
412- 459 (59.70/38.86) YmghiliaTDSigQVSCY.RINFDHIMNNLVH.AANLFE.....FCMISGLDTLD
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