<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10870

Description "CLUMA_CG017166, isoform A"
SequenceMGCSFPVVKMAKWGEGDPRWIVEERPDATNVNNWHWKESNATGWSKDKLNELFLLFEISDGNLTSTIIEFEKLQGEAIANNRKGKLIYFYEWDLVLKWQGRILNDESKTKIDGKITIPNLSEENELDEIDITVTVDESNDKSELLKQFMYNVGRTKIREQLGKYIVSLKNDYAKNLILPKKEEVQVHNKPTTTVNHTATNKAVINNSSSAPSKPATDSKSVGVKIDCKTLIFEEKFQCKANELFDCFSKIELMTAFTRGDVKLDFTKNGEFVLFGGNISGKFTEIIPCQKIAQTWRYKQWPTGHFSNVVMEFEEKDDHTLLKLKQTLVPSNEYDSTNQNWQRYYFEIVLAIPFYLIANGRIAVCQNNAEKALEEPTFCLTGTIALPPPNPVICFNQNEIFACAFGEARCDGLGYCGTPPYAGAGMVTNAMPMKIFVNIMIPNNGPNVFLNIDELFIQMALDGMDDVLFPRFREIRSRAQRIKYIEKLLIHHNLIGDKKNFTYDKSSPKAIAIAEISRECGNRNFKRKDYWEAVKWYNQCLGFAYLGSKQEADAYASRAEVCFELRFLGECLKNIEWAEACNVTKEKLAALEKRKKLVLEMIANGEGFNNPMYAIGHQFLGLNMDTSENYPMADCFEVKTDKAFGRHVITNKKLRVGDIFCIDEPFSKILFAEYGCEFCAYCLSNNALDLIPCKICTHVMFCSDQGSKSCAKMGYEKFHKYECGLITGLHNTGEIEWRAAFNTFLEGFYACNQNLREFKRVAAENCDSKKTIFDFDDLSDRRNLFRIIDAIPKTKKGNTFDDFKICAKTAIITHLFMKHSPLKEVLKSEDDQEFFRLCIYKYSQQCGYSRVSHSSLKGDELNFLPYHAIGTYPFFSLVNHSCAANIIRVNYGSKSIGVAIRPIQPGEQIFLNYQVNHDLYDYAYRRNFLMKNFSFICKCEACTFNYGQSRDLSLVDMRLTNSILYSDRPHLIKASFDLAKSKYRHYFKILQMIDNEYPTLDISCVRECVRTASCGVYLNEMKTNYIVPALEYFSQGMEDIYSPSNKSAGSLFGIVSFKTSQCIPNNTCNTFGPFISPQKFLKTIDNLDLTGGKSECNANMAEGLATALVCFQDLEKLRDKEITTNKHCILISNSSPYSMPVTECYEYEGKTVEQLAAIFMEKNINLSIISPRKIPVLFEIFEKSGGDLVLTTSKNYSKDPRHLVLLKGFSLKERPASPNVNQSGQPNQLPPSQPVANPQPTTIIQNNDANIHAAQINVNNPGIRQMNPNIRQNTAPIMQAPNQQQQQQPIPGQMVNAIPPQFVGAQQNMGNFQQRPTNQQQQQPQPHPRWIAPNQSRQPFMPTQGNMSGNNIMGGANIAPNNMMQQTQGNQNQPQQNSALISQLTQPSNIAMTPQQQAMARMAAMQNQQQNQQMMQNQLGNNNMNMVPNQLQNNPQMMPTNQQAMQGIPGSGLVQQNPSVSQQSGQQIIQCEISARVSKETNEVEVRGDTWPPRLIMQLMPRAVITNVGGHLLRDAKIVNFHWGQPSEAFEALSKVMANGFAGCVHFMPSQCDVKILILLYMPEKKSYYGFIPNDQNGYVDKLRRVIQQSKTTQFGQTPGPPNPQQVGPRGQIMGMNPIVQQNVMNQQVGQQNMGNVGNMQGQGDQSMMFNQQMQQMQPNMVSNQPMNPNQQRMTRPQNIMQNNLRHLLQQQQNQFRPQMGQQQQQQQQQQQPNQQMHGGMDPNFDMF
Length1727
PositionUnknown
OrganismClunio marinus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Chironomoidea> Chironomidae> Clunio.
Aromaticity0.09
Grand average of hydropathy-0.494
Instability index42.73
Isoelectric point8.16
Molecular weight196161.77
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
ATPase activator activity	GO:0001671	IEA:InterPro
chaperone binding	GO:0051087	IEA:InterPro
Hsp90 protein binding	GO:0051879	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10870
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            12|     422.60|      31|      33|    1260|    1290|       1
---------------------------------------------------------------------------
 1229- 1279 (39.07/13.50)	PPS.....Q.PVANPQPttiiqnndanihaaqinvnnPG...IRQMNPN.I...R..QNTA.P..IMQ....A
 1280- 1314 (41.32/14.72)	PNQ.....Q.QQQQPIP......................gqmVNAIPPQ.FvgaQ..QNMG.N..FQQ....R
 1315- 1331 (32.88/10.14)	PTN.....Q.QQQQPQP...........................................H.P..RWI....A
 1332- 1369 (26.34/ 6.57)	PNQ.....S.RQ..PFM....................PT...QGNMSGNnI...MggANIA.PnnMMQqtqgN
 1370- 1404 (34.94/11.26)	QNQ.....P.QQNSALI...............sqltqPS...NIAMTPQ.....Q..QAMA.R..MAA....M
 1405- 1437 (36.79/12.26)	QNQ.....Q.QNQQMMQ...............nqlgnNN...M.NMVPN.Q...L..QNNP.Q..MM......
 1438- 1469 (27.40/ 7.15)	PTN.....Q.QAMQGIP...................gSG...LVQQNPS.V...S..QQSGqQ..IIQ.....
 1600- 1623 (39.26/13.61)	PPN.....P.QQVGPRG....................QI...MG.MNPI.V...Q..QN.............V
 1624- 1648 (37.98/12.91)	MNQ.....Q.VGQQN.M....................GN...VGNM........Q..GQGD.Q..SM.....M
 1649- 1680 (47.98/18.35)	FNQ.....QmQQMQPNM....................VS...NQPMNPN.Q...Q..RMTR.P..QNI....M
 1681- 1703 (26.76/ 6.80)	QNNlrhllQ.QQQN..................................Q.F...R..PQMG.Q....Q....Q
 1704- 1724 (31.87/ 9.59)	QQQ.....Q.QQQQPNQ....................QM...HGGMDPN.F......................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.77|      46|     301|     377|     427|       2
---------------------------------------------------------------------------
  377-  427 (76.66/63.63)	FCLT.GTIALPPPNpvICfnQNEIFACAFGEARCDGLGYCGTPPYaGAGMVT
  680-  726 (85.11/52.59)	YCLSnNALDLIPCK..IC..THVMFCSDQGSKSCAKMGYEKFHKY.ECGLIT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     120.20|      31|      33|    1118|    1148|       3
---------------------------------------------------------------------------
  199-  217 (20.34/ 6.48)	.......TNKAVINNSSSAP.SKPAT.D......
 1118- 1148 (59.14/31.35)	DK..EITTNKHCILISNSSPYSMPVT.ECYEYEG
 1152- 1184 (40.72/19.55)	EQlaAIFMEKN.INLSIISPRKIPVLfEIFEKSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.83|      30|      35|     887|     920|       4
---------------------------------------------------------------------------
  887-  920 (48.73/34.39)	RVNYGSKSIGVairpIQPGEQIFLNYQVNHD..LYD
  924-  955 (52.10/27.78)	RRNFLMKNFSF....ICKCEACTFNYGQSRDlsLVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.26|      22|     251|      34|      60|       5
---------------------------------------------------------------------------
   34-   60 (35.87/32.74)	WHWKEsnatgWSKDKLNELFLLFEISD
  295-  316 (43.39/26.85)	WRYKQ.....WPTGHFSNVVMEFEEKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.60|      30|      33|     548|     577|       6
---------------------------------------------------------------------------
  548-  577 (52.27/35.81)	KQEADAYASRAEVCFELRFLGECLKNIEWA
  584-  613 (49.33/33.35)	KEKLAALEKRKKLVLEMIANGEGFNNPMYA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.14|      26|      33|    1035|    1064|      10
---------------------------------------------------------------------------
 1035- 1064 (32.94/33.87)	GmeDIYSPSN..KSAGSLfGIVSFKtSQCIPN
 1071- 1098 (41.20/23.54)	G..PFISPQKflKTIDNL.DLTGGK.SECNAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.48|      15|     298|    1199|    1227|      11
---------------------------------------------------------------------------
   18-   32 (30.52/12.03)	PRWIV.......EERPDATNVN
 1199- 1220 (22.96/40.38)	PRHLVllkgfslKERPASPNVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.70|      38|     366|     460|     500|      12
---------------------------------------------------------------------------
  460-  500 (58.91/59.14)	LDGMDDVLFPRFrEIRSRAQRIKYieKLLIHHNLIGDKKNF
  825-  862 (69.79/55.92)	LKSEDDQEFFRL.CIYKYSQQCGY..SRVSHSSLKGDELNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.17|      47|     365|     616|     667|      13
---------------------------------------------------------------------------
  616-  667 (69.66/59.84)	HQFLGLNMDTSEnYPMAD..CFE..VKTdKAFGrhVITNkKLRVGDIFCIDEPFSK
  984- 1034 (78.51/46.75)	HYFKILQMIDNE.YPTLDisCVRecVRT.ASCG..VYLN.EMKTNYIVPALEYFSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.69|      10|      23|    1515|    1524|      14
---------------------------------------------------------------------------
 1515- 1524 (20.59/12.35)	AKIVNFHWGQ
 1541- 1550 (20.11/11.88)	AGCVHFMPSQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10870 with Med25 domain of Kingdom Metazoa
Unable to open file!