<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10862

Description "CLUMA_CG012997, isoform A"
SequenceMKYPKMAMVPPQQQQQPMDNISKVKSLLQPLREALKNVFTAAAHLLNQNNLPNDKQTPRFDKYLEVFFSICDQIEQNLITAKKCIQQSSNAQVYLPVPVVTTAQENALSYMQFRDLVNTQISYAKDVHDTLVGGNANASSFFRQHNCNTSDAQQKYTSRAAQLYRDKLSNLAQQACKLHGSTLIINEPHYHHEETKVESDFFADCENANFNSEENVETSTNNIELPTTKPQVSLGSFLDNDGAEPSVDFLHSNVPIEAPKSNIGVRKIQPKKGGIGAKKGLGATKVKTNFADIEQRATLADQMKEPIIEKKLTEEEEAEAITSVRLAYQDLSLQKQKEEERLKNVDPNKAKQMERLGMGFGNRGGVSHSMLTDMQTINQDQAPLSMKSSSKNDNNSKSSDFFDDYSTSMYSNNSSSSNSKQDFRDAMMMGFEPIDSKQDIHTMFSPVEKKESSNKNVNDRQPSSSSFTRNNRETKSSVTTPSNNYDTDSIQKKFAGAKGISSDQFFGNEQSSFEKSANLSKFQGSSSISSADYFGDGTQSNTSRRKKFKEFKFKE
Length555
PositionTail
OrganismClunio marinus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Chironomoidea> Chironomidae> Clunio.
Aromaticity0.08
Grand average of hydropathy-0.850
Instability index47.71
Isoelectric point6.82
Molecular weight62162.34
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10862
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.41|      19|      27|     493|     519|       1
---------------------------------------------------------------------------
  493-  511 (35.96/34.56)	KFAGAKGISSDQFFGN.EQS
  521-  540 (31.46/12.67)	KFQGSSSISSADYFGDgTQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.47|      15|      15|     395|     409|       2
---------------------------------------------------------------------------
  395-  409 (27.71/15.41)	NSKSSDFFDDYSTSM
  413-  427 (26.76/14.63)	NSSSSNSKQDFRDAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.79|      19|      27|      37|      55|       3
---------------------------------------------------------------------------
   37-   55 (31.96/22.28)	NVFTAAAHLLNQNNLPNDK
   65-   83 (31.84/22.16)	EVFFSICDQIEQNLITAKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.39|      21|      28|      99|     126|       4
---------------------------------------------------------------------------
  103-  126 (26.53/36.84)	AQENALSYmqFRDLvNTQISYAKD
  134-  154 (37.85/21.70)	GNANASSF..FRQH.NCNTSDAQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.89|      27|      29|     216|     242|       5
---------------------------------------------------------------------------
  216-  242 (43.43/28.48)	VETSTNNIELPTTKPQVSLGSFLDNDG
  247-  273 (44.46/29.31)	VDFLHSNVPIEAPKSNIGVRKIQPKKG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10862 with Med29 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IDSKQDIHTMFSPVEKKESSNKNVNDRQPSSSSFTRNNRETKSSVTTPSNNYDTDSIQKK
2) KQKEEERLKNVDPNKAKQMERLGMGFGNRGGVSHSMLTDMQTINQDQAPLSMKSSSKNDNNSKSSDFFDDYSTSMYSNNSSSSNSKQDFRDAMMMGFE
434
335
493
432










Molecular Recognition Features






MoRF SequenceStartStop




1) SISSADYFGDGT
2) TSRRKKFKEFKFKE
527
542
538
555