<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10859

Description "CLUMA_CG012147, isoform A"
SequenceMERVGKIIDNVLKMDFIELSFSDISVYRQDQEEMKVKKFSEQMESFFNSLTSESKEAALLIYITKCEKANLSQLKILFDTLDLLVKNNVLTARVVCEQILTSEKLDYKNELFFTECFKMIKKLIGGVDYKGVREIMKGCREKANSFPNEMPSSLLPQLLSVNDVLKYIFDRNACLLPAYFIITELQKQENAEVHWKISNLTATFIEEFVNLAQMLSIIGHSTLYPILEPASAAGYGEATNPWRLDPNTLKFTTLKGNLPYDSQLTQPQVGLLRYVLQQLYSKEMVCSMLNLQKQRSAVLEEQIVWLVILAMEKSEQDSSLSDAKADPNDSTPTHNQWLWLHLSSQLIYFVLFQCAAFPNIVNTLHEKLSTMTLRKGRDDLMWALLQYISGSIQRNALSNFLPVLKLYDILYNEKEPLAVPDVKLPSSTKKIAATCIYIHLLKKAQLENVALRPIPIALKKHYEFLQHLSSAQNSSLSIGDDYVVTLLCNAYSTNQEYFSRPMSALIDTILSTSKPPTQVVSQQSLPTQSPLSMIVLDSLTVHSKMSVIHCIVNNMMKQAETKTTMPNLSPNISPALVETYSRLLVYTEIESLGIKGFLSRLLPTVCKSNAWSILYTLLEMFSYRLFHIQAHYRAQLLTQLHTLSQNAHVNQTQLHLCFESTALRLLTGLGSAEFQFQLSRFLTEPKNLASMVSADSEELNRVLVLTLARSMIITGMENETNSGNSNIVCLMDLLGVIMKNTPHNWSSHTKQSFPKVLSDFYANHNLPVEDKQQVKKAIEEEYRNWLSMTNENDIISYFSQTSSFLCLLFKIISETGEMSPVAFKILERIGARTFSAQLRKLCDFLLYEVTISKQIPKLVDTISDMIWKFNIVTIDRLVLCLALRTQEPNQQDMPTAQVFVIQLLLIKTSQFRDRVMKFVEKNSPEYWKQSNYNEKHLAFHKEFPEKFVPSDEHYSTFFGNVCLRFLPVLDIVIHRYLEMSSIEAVSNSLESVLKTLGLLYKFHDRPITYLYNTLFYYEMKLRDRPALKRLLVGAIITSLKDVREKNWALTEQYQLYIKNQLSPDDQPIKWNPDLSYYRGLVKRLIETIDGRNVFPNVDWRFNEFPNPPTHALYVTCVELLGLPTIPKVVANNIIDVAIKGYIVITQQNYANIHSWINAIGLIISALPEPYWSVIYDRLEEILKHPQMIEWTYRQSPFDMFSFKTVQYALLETKFVMILALTHSIFHHFSIGQTSKIVQYVKERLVPHIKTEHQLIYLHHVLGPFLQRLDPKDVIEITKIYYELLELVDKKNSLTEETMRYQDSLCDMLYHIKYMFVGDSMKTDLEPIIKRLSSPLRLRLRFITRLSVEEIKAEKNVEPKAVKLQTNVLQSVKINRM
Length1376
PositionTail
OrganismClunio marinus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Chironomoidea> Chironomidae> Clunio.
Aromaticity0.10
Grand average of hydropathy-0.089
Instability index44.92
Isoelectric point7.74
Molecular weight158769.65
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10859
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     622.36|     227|     377|       5|     380|       1
---------------------------------------------------------------------------
    5-  301 (302.86/328.28)	GKIIDNVLKmDFIE.LSFSDIsVYrQDQEEMKVKKFseQMESffnsltSESKEAALLIYITKCEKANLSQ.........LKILFDTLDLL..VKNNVLtarvvceqiltSEKLDYK..........NELFFTecfKMIKKLIGGvdykgvreIMKGCREKA.....NSFPNEMPSSLLP.QLLSVNDVLKYIFdrnaCLlpayfiITELQKQ.ENAEVHWKIS.NLTATFIEEFVNL.....AQMLSIIG..............HSTLYPILEPASAagygeatnpwRLdpntlkfttLKGNLPYDSQL.............TQPQVGL......LRyVLQQLYSKEmvcsmlnLQKQRSAVLEE
  390-  684 (319.50/217.55)	GSIQRNALS.NFLPvLKLYDI.LY.NEKEPLAVPDV..KLPS......STKKIAATCIYIHLLKKAQLENvalrpipiaLKKHYEFLQHLssAQNSSL...........SIGDDYVvtllcnaystNQEYFS...RPMSALIDT........ILSTSKPPTqvvsqQSLPTQSPLSMIVlDSLTVHSKMSVIH....CI......VNNMMKQaETKTTMPNLSpNISPALVETYSRLlvyteIESLGIKGflsrllptvcksnaWSILYTLLEMFSY..........RL.........FHIQAHYRAQLltqlhtlsqnahvNQTQLHLcfestaLR.LLTGLGSAE.......FQFQLSRFLTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     647.25|     222|     377|     727|     992|       2
---------------------------------------------------------------------------
  727-  992 (315.39/287.04)	IVClMDLLGVimkntPhnwsshtkqSFPKVLsdfyANHNLPVEDKQQVkKAIEEEYRNWLSMTNE.NDIIS.....YFSQTSSFLCLLFK...IISETGEMSP........VAFKILErigaRTFSAQLrKLCDFLLYEVTISkQIPKLVDTISDMIWKfNIVTIDRL.....VLCLALRTQEPnqQDmptaqvfviqllLIKTSQFRDRVMKFVEKNSPEYWKQSNYNEK..HLAFHKEFpeKFV.........PSDEHYSTFFgNVCLRF...LPVLDIVIHRYLEMSSIEAVSNSLESV
 1114- 1371 (331.86/200.46)	VTC.VELLGL.....P.........TIPKVV....ANNIIDVAIKGYI.VITQQNYANIHSWINAiGLIISalpepYWSVIYDRLEEILKhpqMIEWTYRQSPfdmfsfktVQYALLE....TKFVMIL.ALTHSIFHHFSIG.QTSKIVQYVKERLVP.HIKTEHQLiylhhVLGPFLQRLDP..KD............VIEITKIYYELLELVDKKNSLTEETMRYQDSlcDMLYHIKY..MFVgdsmktdlePIIKRLSSPL.RLRLRFitrLSVEEIKAEKNVEPKAVKLQTNVLQSV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10859 with Med23 domain of Kingdom Metazoa
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