<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10855

Description "CLUMA_CG009921, isoform A"
SequenceMSENSLEGLENQLELFCENIRQIGIIVSDFQPQGQAVLNQKIQTLISDLQKIDKSRKNVVGDIHIPLAVFDYIDQGRNPQLYTKDCIEKALNKNEETKGSTPSNMPLFGKSQKSPAELVKALKEALKALEALKTLERGDKKAEKAQEDVSKNLASIKNMLYGTSDTEPQTDIVVSQLAQELYNSNLLLLLIQNLNRIDFEGKKDVAQVFNNVLRRQIGTRSPTVEYICTKPEILFALMAGYEHQEIALNCGTMLRECARYEALAKIMLHSEEFFNFFQYVEVSTFDIASDAFSTFKELLTRHKILCAEFLEANYDKVFTHYQRLLNSENYVTRRQSLKLLGELLLDRHNFTVMTKYISNPDNLKLMMNMLREKSRNIQFEAFHVFKVFVANPNKPKPILEILLRNQDKLVEFLTRFHTERSEDEQFNDEKAYLIKQIKELKPITDGTTSQQQ
Length452
PositionMiddle
OrganismClunio marinus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Chironomoidea> Chironomidae> Clunio.
Aromaticity0.08
Grand average of hydropathy-0.419
Instability index39.53
Isoelectric point6.16
Molecular weight52109.15
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP10855
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     161.26|      40|      44|     359|     398|       1
---------------------------------------------------------------------------
  253-  304 (19.17/ 7.34)	...............................MLRECARyealakimlhseeffnffqyvevstfDIASDAFSTFKELLT...RHK.I
  313-  359 (23.27/10.39)	NYDKvfthyqrllnsenyvtrrqsL.KLLGELLLDR................................HNFTVMTKYISN.......
  360-  398 (63.86/40.56)	.PDN....................L.KLMMNMLREKSR..........................NIQFEAFHVFKVFVANPNKPKPI
  405-  443 (54.95/33.94)	NQDK....................LvEFLTRFHTERSE..........................DEQFNDEKAY..LIKQIKELKPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.38|      28|      51|      88|     115|       2
---------------------------------------------------------------------------
   88-  115 (48.29/35.06)	EKALNKNEETKGSTPSNMP.....LFGKSQKSP
  136-  168 (40.08/27.86)	ERGDKKAEKAQEDVSKNLAsiknmLYGTSDTEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.50|      27|     144|      22|      59|       3
---------------------------------------------------------------------------
   33-   59 (45.11/51.83)	QGQAVLNQKIQT.........LISDLQKID.KSRKNV
  169-  205 (32.40/14.23)	QTDIVVSQLAQElynsnllllLIQNLNRIDfEGKKDV
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP10855 with Med10 domain of Kingdom Metazoa

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