<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10851

Description "CLUMA_CG007010, isoform A"
SequenceMDFDFKVKTQNERTKVEDLFDYEGCKVGRGTYGHVYKGHRKEGNDNKDYALKQIEGTGLSMSACREIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKAAKKPVLVPKGMVKSLLYQILDGIHYLHTNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRKMPEHNTLTKDFKRSSYASCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMVDEYFSESPQPTQDVFAGGPIPYPKREFLTDEEEDKSDSKRQGQAQQSQNQQQQSGNNQQGNGGNSNNDHSNSAKRPRLSGNQQQSNNQNQQQMQQEYHQSQQNQQNQMLFNQNQNNFQQRY
Length452
PositionKinase
OrganismClunio marinus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Chironomoidea> Chironomidae> Clunio.
Aromaticity0.09
Grand average of hydropathy-0.857
Instability index46.83
Isoelectric point8.69
Molecular weight52585.70
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10851
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.75|      16|      16|     365|     380|       1
---------------------------------------------------------------------------
  365-  380 (29.87/14.72)	DKSDS.KR...QGQAQQSQN
  383-  398 (27.51/13.06)	QQSGN.NQ...QGNGGNSNN
  399-  418 (20.37/ 7.99)	DHSNSaKRprlSGNQQQSNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.02|      10|      22|     419|     428|       3
---------------------------------------------------------------------------
  419-  428 (20.45/10.72)	QNQQQMQQEY
  443-  452 (20.57/10.82)	QNQNNFQQRY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10851 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SEQAMVDEYFSESPQPTQDVFAGGPIPYPKREFLTDEEEDKSDSKRQGQAQQSQNQQQQSGNNQQGNGGNSNNDHSNSAKRPRLSGNQQQSNNQNQQQMQQEYHQSQQNQQNQMLFNQNQNNFQQRY
326
452










Molecular Recognition Features






MoRF SequenceStartStop




1) SAKRPRLSG
403
411