<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10840

Description Pre-mRNA-processing protein 40B
SequenceMANNHQYPGIQPFQHPNASSIDLPRGFAPPMNFQNFQCVGRGGTVLSIGYPPQSYAPQLLQSMHHSHERPSQLNQVQVQHVPLGPPTLISQPNVSIASGTSLHQPYVQTPDIGMPGFGGPRALFSYPSATSYEGSRVPPQVTGPSIHSQAQQRASIIHTSAESSIMNPTFEQPKAAFLKPLPSQKALTDWVEHTSADGRKYFFNKRTKKSTWEKPVELMTLFERADARTDWKEHSSPDGRKYYYNKITKQSTWTMPEEMKIVREQAEIASVQGPHAEGIIDASEVLTRSDTASTAAPTGLPSQTSTSEGVEKLTLTSDLKQPASVPGSSSPVENVDRVQMSADETSQLCDTSETDGLSVPVTETSAATLVEKDEISVGNSGDSDDMSTKNANQGSGSGPKESQKPMVESEKVESQTEEKQIHQESFSFNNKLEAVDVFKSLLKSAKVGSDWTWEQAMREIINDKRYGALRTLGERKQAFNEFLLQTKRAAEEERLARQKKLYEDFKRMLEECVELTPSTRWSKTVTMFEDDERFKALEREKDRRNIFEDHVSELKEKGRVKALEDRKRNIIEYKRFLESCNFIKPNSQWRKVQDRLEVDERCSRLEKIDQLEIFQEYLRDLEREEEEKKKIQKEELKKVERKHRDEFHGLLDEHIATGELTAKTIWRDYLMKVKDLPVYSAIASNSSGATPKDLFEDAVEDLKKRDHELKSQIKDVLKLRKVNLSAGSTFDEFKVSISEDIGFPLIPDVRLKLVFDDLLERAKEKEEKEARKQTRQTEKLVDMLRSFKDITASSSWEELKHLVEGSEKCSTIGDESFRKRCFEDYVSLLKEQSNRIKQNKKVPEDVREEHDKGRDKYGREKDRVRERDSDDHHKKGAAGKYNHDMNEPHGKERRRSGRDSHNRHRERHTSVKENDTDHFKESHKAGGGHKKSRHQRGWVSEAEVEGKEKRRRKEEAREHTKEEELEDGECGRY
Length973
PositionUnknown
OrganismArabidopsis thaliana (Mouse-ear cress)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Camelineae> Arabidopsis.
Aromaticity0.07
Grand average of hydropathy-1.027
Instability index47.56
Isoelectric point6.46
Molecular weight111485.10
Publications
PubMed=11130713
PubMed=17272265
PubMed=27862469

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10840
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     161.72|      39|      39|     188|     226|       1
---------------------------------------------------------------------------
  177-  217 (70.74/44.40)	FLKPLPSQKalTDWVEHTSADGRKYFFNKRTKKSTWEKPVE
  218-  258 (69.95/43.81)	LMTLFERADarTDWKEHSSPDGRKYYYNKITKQSTWTMPEE
  438-  455 (21.03/ 7.87)	FKSLLKSAKvgSDW....................TWEQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     424.27|      63|      65|     495|     557|       2
---------------------------------------------------------------------------
  495-  557 (103.35/64.76)	LAR.QK........KLYEDFKRMLE.ECV...ELTPSTRWSKTVTMFEDDERFKALEREKD...R...RNIFEDHVSEL....KEK
  563-  628 (80.29/48.51)	LED.RK........RNIIEYKRFLE.SCN...FIKPNSQWRKVQDRLEVDERCSRLEK.ID...Q...LEIFQEYLRDLereeEEK
  629-  703 (60.11/34.31)	KKI.QKeelkkverKHRDEFHGLLD.EHIatgELTAKTIWRDYLMKVKDLPVYSAIASNSSgatP...KDLFEDAVEDL....K..
  705-  765 (61.52/35.30)	..R.DH........ELKSQIKDVLKlRKV...NLSAGSTFDEFKVSISEDIGF.PLIPDVR...L...KLVFDDLLERA....KEK
  769-  832 (84.76/51.66)	EARkQT........RQTEKLVDMLR.SFK...DITASSSWEELKHLVEGSEKCSTIGDESF...R...KRCFEDYVSLL....KEQ
  836-  872 (34.24/16.10)	IKQ.NK........KVPED........................VREEHDKGRDK.YGREKD...RvreRD.SDDH...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.93|      45|      55|     873|     919|       3
---------------------------------------------------------------------------
  873-  919 (76.37/50.68)	HKKGAAGKYNHDMNEPHGKERRRsgRDSHNRHRERHTSVKENDTDHF
  929-  973 (77.56/45.49)	HKKSRHQRGWVSEAEVEGKEKRR..RKEEAREHTKEEELEDGECGRY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.74|      27|      55|      24|      50|       5
---------------------------------------------------------------------------
   24-   50 (49.32/35.64)	PRGFAPPMNFQNFQCVGRGGTVLS...IGY
   52-   80 (38.92/26.43)	PQSYAPQL.LQSMHHSHERPSQLNqvqVQH
   82-  106 (42.50/29.60)	PLG..PPTLISQPNVSIASGTSLH...QPY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.58|      28|      28|     305|     332|       6
---------------------------------------------------------------------------
  288-  315 (42.47/27.56)	RSDTASTAAPTGLPSQT...STSEGVEKLTL
  316-  340 (39.86/25.37)	TSDLKQPASVPGSSSPV...E...NVDRVQM
  345-  375 (35.25/21.51)	TSQLCDTSETDGLSVPVtetSAATLVEKDEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.18|      14|      30|     128|     144|       7
---------------------------------------------------------------------------
  128-  144 (21.07/23.90)	SAtsyEGSRVPPQVTGP
  160-  173 (26.12/17.86)	SA...ESSIMNPTFEQP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10840 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EGSRVPPQVTGPSIHSQAQQRASIIHTSAESSI
2) QSNRIKQNKKVPEDVREEHDKGRDKYGREKDRVRERDSDDHHKKGAAGKYNHDMNEPHGKERRRSGRDSHNRHRERHTSVKENDTDHFKESHKAGGGHKKSRHQRGWVSEAEVEGKEKRRRKEEAREHTKEEELEDGECGRY
3) TMPEEMKIVREQAEIASVQGPHAEGIIDASEVLTRSDTASTAAPTGLPSQTSTSEGVEKLTLTSDLKQPASVPGSSSPVENVDRVQMSADETSQLCDTSETDGLSVPVTETSAATLVEKDEISVGNSGDSDDMSTKNANQGSGSGPKESQKPMVESEKVESQTEEKQIHQES
133
832
254
165
973
425










Molecular Recognition Features






MoRF SequenceStartStop




1) KYYYNKI
2) RHQRGWVSEAEV
241
933
247
944