<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10825

Description Uncharacterized protein
SequenceMLLLQEKRPLKRSRLGPPDVYPQEAKQREDELTPSNVKHGFATMPPLSDEFGTAHTSNVNASKVASFFNAILAKKEELMTLQDTVRKKQQINFKDNFWPVSPRTKTALDAWFKDLAGNKPLLSLAKKAPSFNKKEEILITLCDHQVNMQRATWFIKLSAAYTASVSESKNKKRNLVDPVTEWTGIMVKFMKDLLPKLQEYYHLSEKCSPAERALMSGYGAPATQNNNPSQINSASHVPNSLTTVPSMASPVPMLSPANNQTSAASTLGGAISNNSTPLVGCSTSQSGIPGSGNMPGSGSSISGTGSNFEDSRNALKYWNYCAQLSKYMHEESLLDRQEFLNWILELLDKMRTQTTFDESLKKLILTFAMQYMHDFVQSERLCRKMAYIVAKKLSNLLNGVIDQQQHINGNQKQLLPAGVTPMDVDEDVEKKKLILDPYETALNEYLSCPHHRDIVLYLSTILQIITIECPTAMVWCGIGENRAPAALCGSPLDHLPLAPSALPMPSKCPITNAEVRRQLKSIESDIVLRSKHAEARWFAEKWQNADKNSYTHVLTILDHLDTHCFDLMDQSNSIDTLYANIFQPFVSVRHEVGANGEMKEIRQEYEASTVDGNTVKILCEWAVSSQRWGEHRAVVVAILLDKRQIEVTTPCAEDLNNGQSNGSNVNDDKDSIASGAGLIGGLPVFQSVLMNFLDHDAPILDENGTVANRTQFTNLVHLFSALIRHDVFSHNAYMYTLISRGDLLEGANGMNGASLNHTKTTTTISNSVTNPVSNKPVSPTINQGFDDDFTSGLDFKHNEYDDSNVDDDLEKILQNIKEKGQVQAPDSPKIPEHNNSSSISRHYIYTKHFPIPQDDPSMSYSSESNQRYILLFGVGKERDEKKHAVKKMSKEICKLFTKKFSIDVAEGGKVKKHSRNEFNFEATTSKCQNMAYFDQHVVTSQCAATVLEQLNGFAVGSNNYLPVQEHVAFLFDLMEMALNIHSLLELCDQILKELPEVENQLQAKKSNMIRSYTTSLGLYIVGILRRYHSCLLLSPDQTISVFEGLCRIIKHVGNPAECSSAERCILAYLNDLYEACHLLRSKEQEAEFFLQISNIKKFKDIINHPEQLGMVPQTYNSQFMQEFFTSPKRGGKIDPLWLRQLHESPANIYSFVSNVIFAVCHEADNDRLNDIAIACAELTAGCNALSEEWIDALCSICKAMNKKRYPHLSQIDIQNSKIHNSLAVFICILVARHCFSLADFVLKFALPTLANAYPDGCEITPDAESGARLTCHLVLKLFKTIEIPQPGMYSVSTSPNPLNAVNSSSNIKLSCDRHLLIAAHKNIPLEAVLAVLKAILIVVDTTALKTPTMAGNNSAGGAFGSGSKRGSGFNTPVHPGSTPKSNDRPVDISQILGTSDLTSLAGDHDHDMSQPLSTTPLNANHGSGGEQISLLEFAQHVLKQICAQEHVLERCLKNSDKLCDMVFDDMLTPKQSQSILHMICYSEAEYSIISELDQRSMIVRILENLGQWTLRISLLDLQLMHKQSINNASELTTWLDTVARAAIDVFLMEEVISPHGGKAEHRPKPSTWLVAPLVSNLTSAVQGRILRVAGQVLESMNYFSKTSKADNNSSCSGDEREKSNSCGSASSSYSGGSNGSSRSKKMPLNYQPFLGLILTCLKGQDEYKENLLVSLYSQLSQCLQSYAEFDTMGGVDDPQGREEMLDALQLRFSLVGGMFDSILKNGTSITDWAILLAQLVCQGVIDQSTNRELFTSVVDMLTTLVHSTLVSDSQSERDEKFYSNLMKKLKKEIGEKNNASIKVIRQLLPLYKQPTEVISCEPAGVDQKGNKINDMDKKQLRVSDKQRISVWDILEGHKNPAPLSWVWFGAVKLERKPLTYEEAHRNLKYHTHSLAKPSHYFYEALPLPPEEVEPVPEKIVTPTPPFLQKDEMKADTPSSVDQSPSAVVTGRGRGKGTTRKRKPKNAKTPPVNAQQPAQQITGPQVGQGPQQAGQQQNPITQQQQQQQQQQQQQMVQQQQQQQQQVAQQQQQPMNTQQQMGQMQMNMQMSSNVNMQQFNPNQMMQQNSMMQQQQMQGVPGNMPQQMNVGNPQQNPQMNFMGPSGPQAMQQGAMNPQQQQWQGQNQFHTMQQQQQQQQFYQQQQQGMQQMNRFERPQINNSKQALHNMLRMRQPTFSQNNPNPNFNAMQQQQQQRQAQGIPSQQQPGGLNPVQQQQMQQQQFGRAGMRGMAPNQMAGVAPNQIAPGMGNQVGMGAQGMGGQNPIMQQQMAAQGMNQGNSQMGMNQNAGMMPGAGSSNNPNMMAAQTNNGMVNAGGMMQPNVGVGVGVGGVGNNAVVNQGMVNQSGPAQFQNFNQYQQQGMNQTAGPNQQANLMGGFNQMNQRNNPGDFMAQQQQRGPGAMPGNRGQYINQAPNVTMNNMMGQGNVPPYQRQQSTGGKPGVSQQQFQQQQRMQQMLQMQGMGPQNPGASGMGQAQNQSVGQQQNPNLVAQLQRQMPNQPNMMGQQYQHPPPY
Length2505
PositionKinase
OrganismStomoxys calcitrans (Stable fly) (Conops calcitrans)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Muscoidea> Muscidae> Stomoxys.
Aromaticity0.06
Grand average of hydropathy-0.529
Instability index48.55
Isoelectric point6.86
Molecular weight278229.19
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10825
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            11|     409.66|      25|      25|    1986|    2010|       1
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 1986- 2010 (53.20/20.10)	QQAG....QQQ..NPITQQQQ..QQQQQQQQ..QM
 2012- 2038 (38.76/12.45)	QQQQ....QQQ..QQVAQQQQ..QPMNTQQQmgQM
 2043- 2070 (35.45/10.69)	QMSSnvnmQQF..NP.NQMMQ..QNSMMQQQ..QM
 2072- 2092 (30.37/ 8.00)	GVPG.........N.MPQQMN..VGNPQQNP..QM
 2100- 2124 (35.86/10.91)	PQAM....QQGamNP..QQQQ..WQGQNQFH..TM
 2125- 2141 (32.89/ 9.34)	QQ.Q....Q.........QQQ..QFYQQQQQ..GM
 2169- 2193 (35.47/10.70)	TFSQ....NNP..NPNFNAMQ..QQQQQRQA..QG
 2198- 2221 (41.10/13.69)	QQPG.....GL..NPVQQQQM..QQQQFGRA..GM
 2250- 2275 (38.92/12.53)	QGMG.....GQ..NPIMQQQMaaQGMNQGNS..QM
 2371- 2394 (32.66/ 9.22)	NQMN....QRN..NP.GDFMA..QQQQRGPG..AM
 2424- 2448 (34.98/10.45)	RQQS....TGG..KPGVSQQQ..FQQQQRMQ..QM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     138.78|      24|     194|    2276|    2299|       2
---------------------------------------------------------------------------
 2227- 2249 (26.01/ 6.94)	..N...Q..MAGVAPNqiAPGMGNQVGMGA.
 2276- 2299 (48.34/19.14)	GMN...Q..NAGMMPG..AGSSNNPNMMAAQ
 2325- 2350 (33.45/11.01)	GNN...AvvNQGMVNQ..SGPAQFQNFNQYQ
 2477- 2498 (30.98/ 9.65)	NPNlvaQ..LQRQMPN..QP.....NMMGQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     174.65|      57|     194|    1481|    1544|       3
---------------------------------------------------------------------------
 1481- 1544 (79.32/80.06)	YseAEYSIISELDQRSMIVRILENLgqwTLRISLLDlqLMHKQSINNASELTTWL....DTVARAAID
 1682- 1742 (95.32/69.25)	Y..AEFDTMGGVDDPQGREEMLDAL...QLRFSLVG..GMFDSILKNGTSITDWAillaQLVCQGVID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.69|      38|     412|    1119|    1159|       4
---------------------------------------------------------------------------
 1119- 1159 (61.48/52.12)	FMQEFFTSPkRGGKID.....PLWLrqLHESPANIYSFVSNVIFAV
 1546- 1588 (60.21/39.58)	FLMEEVISP.HGGKAEhrpkpSTWL..VAPLVSNLTSAVQGRILRV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.76|      47|     412|     327|     375|       5
---------------------------------------------------------------------------
  327-  375 (79.00/59.73)	YMHeeSLLDRQEFLNWILEL....LDKMRTQTTFDESL......KKLILTFAMQYMHDF
  733-  789 (70.75/47.01)	YMY..TLISRGDLLEGANGMngasLNHTKTTTTISNSVtnpvsnKPVSPTINQGFDDDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.37|      17|     194|     602|     618|       6
---------------------------------------------------------------------------
  602-  618 (29.48/24.92)	RQEYEASTVDGNTVKIL
  797-  813 (30.89/26.57)	HNEYDDSNVDDDLEKIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     131.18|      42|     412|     538|     588|       9
---------------------------------------------------------------------------
  538-  588 (62.08/63.48)	FAekwqnADKNSYTHVLTILDHLdthcFDLMDQSNSIDT...LYANIFQPFVSV
  953-  997 (69.10/44.70)	FA.....VGSNNYLPVQEHVAFL....FDLMEMALNIHSlleLCDQILKELPEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.74|      16|     411|    1966|    1981|      10
---------------------------------------------------------------------------
 1921- 1936 (23.12/11.90)	PFLQKDEMKADTPSSV
 1966- 1981 (27.63/15.99)	PVNAQQPAQQITGPQV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10825 with Med12 domain of Kingdom Metazoa
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