<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10824

Description Uncharacterized protein
SequenceMLLLQEKRPLKRSRLGPPDVYPQEAKQREDELTPSNVKHGFATMPPLSDEFGTAHTSNVNASKVASFFNAILAKKEELMTLQDTVRKKQQINFKDNFWPVSPRTKTALDAWFKDLAGNKPLLSLAKKAPSFNKKEEILITLCDHQVNMQRATWFIKLSAAYTASVSESKNKKRNLVDPVTEWTGIMVKFMKDLLPKLQEYYHLSEKCSPAERALMSGYGAPATQNNNPSQINSASHVPNSLTTVPSMASPVPMLSPANNQTSAASTLGGAISNNSTPLVGCSTSQSGIPGSGNMPGSGSSISGTGSNFEDSRNALKYWNYCAQLSKYMHEESLLDRQEFLNWILELLDKMRTQTTFDESLKKLILTFAMQYMHDFVQSERLCRKMAYIVAKKLSNLLNGVIDQQQHINGNQKQLLPAGVTPMDVDEDVEKKKLILDPYETALNEYLSCPHHRDIVLYLSTILQIITIECPTAMVWCGIGENRAPAALCGSPLDHLPLAPSALPMPSKCPITNAEVRRQLKSIESDIVLRSKHAEARWFAEKWQNADKNSYTHVLTILDHLDTHCFDLMDQSNSIDTLYANIFQPFVSVRHEVGANGEMKEIRQEYEASTVDGNTVKILCEWAVSSQRWGEHRAVVVAILLDKRQIEVTTPCAEDLNNGQSNGSNVNDDKDSIASGAGLIGGLPVFQSVLMNFLDHDAPILDENGTVANRTQFTNLVHLFSALIRHDVFSHNAYMYTLISRGDLLEGANGMNGASLNHTKTTTTISNSVTNPVSNKPVSPTINQGFDDDFTSGLDFKHNEYDDSNVDDDLEKILQNIKEKGQVQAPDSPKIPEHNNSSSISRHYIYTKHFPIPQDDPSMSYSSESNQRYILLFGVGKERDEKKHAVKKMSKEICKLFTKKFSIDVAEGGKVKKHSRNEFNFEATTSKCQNMAYFDQHVVTSQCAATVLEQLNGFAVGSNNYLPVQEHVAFLFDLMEMALNIHSLLELCDQILKELPEVENQLQAKKSNMIRSYTTSLGLYIVGILRRYHSCLLLSPDQTISVFEGLCRIIKHVGNPAECSSAERCILAYLNDLYEACHLLRSKEQEAEFFLQISNIKKFKDIINHPEQLGMVPQTYNSQFMQEFFTSPKRGGKIDPLWLRQLHESPANIYSFVSNVIFAVCHEADNDRLNDIAIACAELTAGCNALSEEWIDALCSICKAMNKKRYPHLSQIDIQNSKIHNSLAVFICILVARHCFSLADFVLKFALPTLANAYPDGCEITPDAESGARLTCHLVLKLFKTIEIPQPGMYSVSTSPNPLNAVNSSSNIKLSCDRHLLIAAHKNIPLEAVLAVLKAILIVVDTTALKTPTMAGNNSAGGAFGSGSKRGSGFNTPVHPGSTPKSNDRPVDISQILGTSDLTSLAGDHDHDMSQPLSTTPLNANHGSGGEQISLLEFAQHVLKQICAQEHVLERCLKNSDKLCDMVFDDMLTPKQSQSILHMICYSEAEYSIISELDQRSMIVRILENLGQWTLRISLLDLQLMHKQSINNASELTTWLDTVARAAIDVFLMEEVISPHGGKAEHRPKPSTWLVAPLVSNLTSAVQGRILRVAGQVLESMNYFSKTSKADNNSSCSGDEREKSNSCGSASSSYSGGSNGSSRSKKMPLNYQPFLGLILTCLKGQDEYKENLLVSLYSQLSQCLQSYAEFDTMGGVDDPQGREEMLDALQLRFSLVGGMFDSILKNGTSITDWAILLAQLVCQGVIDQSTNRELFTSVVDMLTTLVHSTLVSDSQSERDEKFYSNLMKKLKKEIGEKNNASIKVIRQLLPLYKQPTEVISCEPAGVDQKGNKINDMDKKQLRVSDKQRISVWDILEGHKNPAPLSWVWFGAVKLERKPLTYEEAHRNLKYHTHSLAKPSHYFYEALPLPPEEVEPVPEKIVKDEMKADTPSSVDQSPSAVVTGRGRGKGTTRKRKPKNAKTPPVNAQQPAQQITGPQVGQGPQQAGQQQNPITQQQQQQQQQQQQQMVQQQQQQQQQVAQQQQQPMNTQQQMGQMQMNMQMSSNVNMQQFNPNQMMQQNSMMQQQQMQGVPGNMPQQMNVGNPQQNPQMNFMGPSGPQAMQQGAMNPQQQQWQGQNQFHTMQQQQQQQQFYQQQQQGMQQMNRFERPQINNSKQALHNMLRMRQPTFSQNNPNPNFNAMQQQQQQRQAQGIPSQQQPGGLNPVQQQQMQQQQFGRAGMRGMAPNQMAGVAPNQIAPGMGNQVGMGAQGMGGQNPIMQQQMAAQGMNQGNSQMGMNQNAGMMPGAGSSNNPNMMAAQTNNGMVNAGGMMQPNVGVGVGVGGVGNNAVVNQGMVNQSGPAQFQNFNQYQQQGMNQTAGPNQQANLMGGFNQMNQRNNPGDFMAQQQQRGPGAMPGNRGQYINQAPNVTMNNMMGQGNVPPYQRQQSTGGKPGVSQQQFQQQQRMQQMLQMQGMGPQNPGASGMGQAQNQSVGQQQNPNLVAQLQRQMPNQPNMMGQQYQHPPPY
Length2497
PositionKinase
OrganismStomoxys calcitrans (Stable fly) (Conops calcitrans)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Muscoidea> Muscidae> Stomoxys.
Aromaticity0.06
Grand average of hydropathy-0.530
Instability index48.41
Isoelectric point6.86
Molecular weight277347.18
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10824
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            11|     405.24|      25|      25|    1978|    2002|       1
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 1978- 2002 (53.27/19.61)	QQAG....QQQ..NPITQQQQ..QQ.QQQQQQ..QM
 2004- 2030 (38.70/12.13)	QQQQ....QQQ..QQVAQQQQ..QP.MNTQQQmgQM
 2035- 2062 (35.39/10.43)	QMSSnvnmQQF..NP.NQMMQ..QN.SMMQQQ..QM
 2064- 2084 (30.37/ 7.85)	GVPG.........N.MPQQMN..VG.NPQQNP..QM
 2092- 2116 (35.93/10.71)	PQAM....QQGamNP..QQQQ..WQ.GQNQFH..TM
 2117- 2133 (27.90/ 6.58)	QQQ...............QQQ..QQfYQQQQQ..GM
 2161- 2185 (35.27/10.37)	TFSQ....NNP..NPNFNAMQ..QQ.QQQRQA..QG
 2190- 2213 (41.23/13.43)	QQPG.....GL..NPVQQQQM..QQ.QQFGRA..GM
 2242- 2267 (38.92/12.24)	QGMG.....GQ..NPIMQQQMaaQG.MNQGNS..QM
 2363- 2386 (32.73/ 9.06)	NQMN....QRN..NP.GDFMA..QQ.QQRGPG..AM
 2416- 2440 (35.54/10.51)	RQQS....TGG..KPGVSQQQ..FQ.QQQRMQ..QM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     310.40|     106|     412|    1030|    1159|       2
---------------------------------------------------------------------------
 1030- 1159 (165.32/153.41)	CL.............LLSPDQTISVFEGLC......RIIKHVGnpaecssaERC.ILAYLNDLyeachllrskeqeAEFFLQISNIK...KFKDIINHPEQ....LGMVPQTYNSQFMQEFFTSPkRGGKID.....PLWLrqLHESPANIYSFVSNVIFAV
 1451- 1588 (145.07/90.99)	CLknsdklcdmvfddMLTPKQSQSILHMICyseaeySIISELD........QRSmIVRILENL.............GQWTLRISLLDlqlMHKQSINNASElttwLDTVARAAIDVFLMEEVISP.HGGKAEhrpkpSTWL..VAPLVSNLTSAVQGRILRV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     138.78|      24|     198|    2268|    2291|       3
---------------------------------------------------------------------------
 2219- 2241 (26.01/ 6.80)	..N...Q..MAGVAPNqiAPGMGNQVGMGA.
 2268- 2291 (48.34/18.94)	GMN...Q..NAGMMPG..AGSSNNPNMMAAQ
 2317- 2342 (33.45/10.85)	GNN...AvvNQGMVNQ..SGPAQFQNFNQYQ
 2469- 2490 (30.98/ 9.50)	NPNlvaQ..LQRQMPN..QP.....NMMGQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     145.00|      34|     448|     825|     861|       4
---------------------------------------------------------------------------
  825-  858 (63.13/40.25)	PDSPKI.PEHNNSSSISRHYIYTKHFPIPQDDPSM
 1254- 1288 (53.95/32.43)	PDGCEItPDAESGARLTCHLVLKLFKTIEIPQPGM
 1304- 1324 (27.91/ 7.16)	SSNIKL........SCDRHLLIAAHKNIP......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.76|      47|     412|     327|     375|       5
---------------------------------------------------------------------------
  327-  375 (79.00/62.76)	YMHeeSLLDRQEFLNWILEL....LDKMRTQTTFDESL......KKLILTFAMQYMHDF
  733-  789 (70.75/49.40)	YMY..TLISRGDLLEGANGMngasLNHTKTTTTISNSVtnpvsnKPVSPTINQGFDDDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.37|      17|     193|     602|     618|       6
---------------------------------------------------------------------------
  602-  618 (29.48/17.66)	RQEYEASTVDGNTVKIL
  797-  813 (30.89/18.84)	HNEYDDSNVDDDLEKIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     131.18|      42|     412|     538|     588|       9
---------------------------------------------------------------------------
  538-  588 (62.08/60.04)	FAekwqnADKNSYTHVLTILDHLdthcFDLMDQSNSIDT...LYANIFQPFVSV
  953-  997 (69.10/42.26)	FA.....VGSNNYLPVQEHVAFL....FDLMEMALNIHSlleLCDQILKELPEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     208.60|      67|     426|     193|     266|      18
---------------------------------------------------------------------------
  193-  266 (101.11/73.31)	LLPKLQeyYHLSEKCSpaeRALMSGYGAPATQNNNPSQINSASHVPNSLTTVPS.....MASPVPMLspANNQTSAAST
  639-  710 (107.49/59.17)	LLDKRQ..IEVTTPCA...EDLNNGQSNGSNVNDDKDSIASGAGLIGGLPVFQSvlmnfLDHDAPIL..DENGTVANRT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.98|      15|     448|    1928|    1942|      25
---------------------------------------------------------------------------
 1908- 1922 (24.31/15.35)	VEPVPEKIVKDEMKA
 1928- 1942 (24.67/15.68)	VDQSPSAVVTGRGRG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10824 with Med12 domain of Kingdom Metazoa
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