<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10792

Description Uncharacterized protein
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
Length497
PositionKinase
OrganismMusca domestica (House fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Muscoidea> Muscidae> Musca.
Aromaticity0.09
Grand average of hydropathy-0.876
Instability index55.51
Isoelectric point8.86
Molecular weight57862.71
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10792
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     128.99|      18|      18|     371|     388|       1
---------------------------------------------------------------------------
  371-  388 (37.46/11.23)	KRQQQQAAAQQQQQQQQQ
  391-  408 (30.28/ 7.76)	QQQQQQSQLQAQAQAQQQ
  409-  424 (29.41/ 7.34)	..QQQQQAQQQQQQQQQH
  478-  495 (31.85/ 8.52)	QVQAQQMMFNQQQQNFQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.54|      34|      40|      92|     129|       2
---------------------------------------------------------------------------
   92-  129 (52.30/51.75)	KVFLLIDYAeHDLWhiiKFHRAAKAAKKQVV..VP.RGMVK
  134-  170 (56.24/40.67)	QIFDGIHYL.HSNW...VLHRDLKPANILVMgdGPeRGRVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.94|      17|      87|     209|     265|       3
---------------------------------------------------------------------------
  218-  256 (15.40/77.98)	WaigcifaelltsepifhcrqEDIKtSNPYHHdQLDRIF
  267-  283 (35.55/ 8.01)	W....................EDIK.KMPEHH.TLTKDF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10792 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) TSEQAMQDAYFQEEPLPTQDVFAGCPIPYPKREFLTDDDQEDKSDTKRQQQQAAAQQQQQQQQQQAQQQQQQSQLQAQAQAQQQQQQQQAQQQQQQQQQHSHEPNSKRVRLSGPGGGPQPNQQVHPGQQQQQDFHQQQVAAAAAAQQ
325
471










Molecular Recognition Features






MoRF SequenceStartStop




1) QQHSHEPNSKRVRLSGP
422
438