<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10780

Description Uncharacterized protein
SequenceMEVQALLNNYLKVETIEEAFLSVIVYHPNGEADKASKFTNDIVKAFGNIHPDNKENVVRQYLQKAATVTNANHLKVLMSTLGKLTELHLITAKLLCEKILLCDKLNYENKLFWIESFQLIKKVIHHVDYKNVREIMKITRDKAETFPFNVNVTYIPQLLALEDTIRYIFDRNSCLLPAYFIANEFMKPSLHHWKLNSLMTDALEEFRMTAQMVSIIGHVHMLPIVEHYGYADHMMNSWKLDSNNLTFTYKGTLPFELEEQPQLLRYVLAQSYSKEMVSIMLNLQKQQKQRCTTLEDQLVNLIINAMEMTETNDNAAGSGFNSPEEQIPHNEWAWLHLSSQLIYFVLFQFASFTHIVLALCDKLSKKELRKGRDNLMWILLQFISGSIQKNPIENFFPMFKLFDLLYPEQEPLNLPDCNKSSLLRQMAPICIWIHLMKKARASNMNISRPLPIALKGHYDYLQHLIMPNAIMPMNLGTDFRIILVCNAYSTNQEYFTRPMNLLVEALAGNAKTSTGAPVQPVPYSMVVLDSLTVHSKMSLIHGFVSQMIKHAQCKTSVPTPALIETYARLLVYTEIESLGIKGFLTQLLPSVFKHQAWGMLHTLLEMFSYRLHHIPTHYRVQLISHLHNFAPIPQTNKMQLNLCFESTALRLINGLGSVEFQPQLALYFNEKSPGSVTSAESEELNRVFILSLARAMHITGSGEEIQPLCKDLLSTIMQNTPHSWASHSLACFPPALAEFFTQNNHPVENKQLLKKSVEEEYRTWTSMSNENDIINHFIKPNTSPLFLCLLYKMIWETESISPVAYKILEGISARALSANLRKLCDYLVSEVNSINGKEFIHKCVDSINNMIWKYNVVTIDRVVLCLVLRTQEGNEARVCFLIIQLLLLKTSELRNRVTEFCKENPDHWKQNNWHEKHLSFHQKFPEKFAPDESASHPPLPVYFSNVCLRFLPVLDVVIHRFIEMQHVHQIAEVILDHLSILYKFHDRPITYLYNTLHFYERILRERPSLKKKLVSAVTGAFCDIRPANWCVSEQYKLYLQSPDLLWNPELSYYIKLIARLTETISGKNVFYNTDWRFSEFSNAPSHARYVTCVELLSLPVAPQIVANNLIDVIVKGYALIPQKEIHAYLNSVGIVLAELPEAYWSQIYERLQEVMNSPKMLRWSYRFNAFEMFNFKMVREAMIEKTYAVILAVAHSIFHHMGGFKLGTMIKYISQKLKPCVRTEHQLIFLCHVFGPFLQRIDIEKHNGVASLAILLYEMLEVVDKQHGPAPLEYLDPICDFLYHIKYIYVGNKIRNECEAIIKRLRPALQMRLRFISHLTVEDKHIDNKPPENVQQQQQQQMQNVSNLNTQMAQQQQQQSAPPTNFVNNSMQQQNFGNITNQQQQQLQQGSMQNMANNPSQQQGNQNAPQMSGMPGQQQQATQMTQQQMQQQLQMQQHLMQQQQQQQQGGQMRH
Length1454
PositionTail
OrganismMusca domestica (House fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Muscoidea> Muscidae> Musca.
Aromaticity0.10
Grand average of hydropathy-0.203
Instability index45.92
Isoelectric point7.88
Molecular weight168310.07
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10780
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      61.18|      11|      28|    1347|    1357|       1
---------------------------------------------------------------------------
 1347- 1357 (22.33/ 8.92)	NLNTQMAQQQQ
 1394- 1404 (18.54/ 6.29)	NMANNPSQQQG
 1438- 1448 (20.32/ 7.53)	HLMQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.01|      30|      44|    1346|    1388|       2
---------------------------------------------------------------------------
 1330- 1346 (21.06/ 6.41)	....PP.............ENVQQQQ.QQQMQnvS
 1358- 1391 (48.44/29.29)	QQSAPPTNFVNNsmQQQNFGNITNQQ.QQQLQqgS
 1405- 1434 (47.50/23.18)	NQNAPQMSGMPG..QQQQATQMTQQQmQQQLQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.98|      35|      54|     344|     380|       3
---------------------------------------------------------------------------
  344-  380 (58.50/38.07)	FVLFQFASFTHIVLAL..CDKLSkkELRKGRDNLMWILL
  399-  435 (60.49/34.36)	FKLFDLLYPEQEPLNLpdCNKSS..LLRQMAPICIWIHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.67|      13|      21|    1243|    1255|       5
---------------------------------------------------------------------------
 1243- 1255 (21.32/ 9.69)	IEKHNGVASLAIL
 1263- 1275 (24.35/11.93)	VDKQHGPAPLEYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.10|      33|      57|     917|     954|       7
---------------------------------------------------------------------------
  917-  954 (56.51/42.04)	HLSFHQKFpekfaPDESASHPPLPVYFSNVCLRFLPVL
  977- 1009 (60.59/34.12)	HLSILYKF.....HDRPITYLYNTLHFYERILRERPSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     164.57|      42|      42|     621|     662|       8
---------------------------------------------------------------------------
  588-  613 (41.09/23.37)	LPSV.FKHQAWGMLHTL................LEMFSYRLHH.
  614-  654 (62.26/39.68)	.IPTHYRVQLISHLHNFAP..IPQTNKMQLNLCFESTALRLING
  655-  698 (61.22/38.88)	LGSVEFQPQLALYFNEKSPgsVTSAESEELNRVFILSLARAMHI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.40|      18|      21|      90|     109|      10
---------------------------------------------------------------------------
   90-  109 (24.77/25.36)	ITAKLLCEKILlcDKLNYEN
  114-  131 (30.62/21.76)	IESFQLIKKVI..HHVDYKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.88|      19|      21|    1143|    1161|      11
---------------------------------------------------------------------------
 1143- 1161 (34.30/27.50)	YWSQIYERLQEVMNSPKML
 1165- 1183 (33.59/26.73)	YRFNAFEMFNFKMVREAMI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.02|      12|      21|     172|     186|      12
---------------------------------------------------------------------------
  172-  186 (19.21/17.52)	NSCLLPAYfiaNEF.M
  196-  208 (17.81/ 7.66)	NSLMTDAL...EEFrM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.11|      21|      21|     483|     503|      13
---------------------------------------------------------------------------
  483-  503 (39.27/26.05)	LVCNA.YSTNQEYFTRPMNLLV
  506-  527 (31.84/19.60)	LAGNAkTSTGAPVQPVPYSMVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.94|      32|      87|    1198|    1232|      16
---------------------------------------------------------------------------
 1198- 1232 (50.37/46.41)	FHHMGGfKLGTMIKYISQKLKPCVRTehQLIFLCH
 1287- 1318 (55.57/37.80)	YIYVGN.KIRNECEAIIKRLRPALQM..RLRFISH
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10780 with Med23 domain of Kingdom Metazoa
Unable to open file!