<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10762

Description Uncharacterized protein
SequenceHLIVCLCYPIKSGEAYAYEADVPEHTSGSVFPKLPTGRDVISLLRARSRSEISLKFARQWPTGDGGRIGLLLGISRPPDARATQSVVVRARAIVTGAARRALVRVPSIIARPGRDRDRDRKRRTADRDRDSRKRKRSRSRDRHRDKDKDKDRDRIARRARARAGRTTKSRSRSRSRGGKRRHRHRSRDHAIADRDRNRDRDRKRDRGKRRRSKRDSCAKQLKRLRTKLARRKGSSRKSRSSSKAQAESEGRSYGSANDSSMADDAIANQPDVAAAAAPRQSGPACLIISSRSAVEFITAGIRYLLTSLASSSWLTTVNNDNEDQPTDAIYPRARAVLLLSNAALLFGYLTEQVDRHRLEHVLAGVRLCCQIDHPIDEEANGRVGLRYWASQALSHGVTLDVFLQFNQSRVDSDGHSSMCFGNSAAPSPYLGAVSIPPPPPRRHPASNHVDPRLCPMCKRPRRNPCALTTSGHVFCFACIHSHLAGNGSAGKCPTGPKLKFADVQVPLAVLKYIDEGRNPQLYTRHCLETALQRNEEVKGKIEEC
Length544
PositionMiddle
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.04
Grand average of hydropathy-0.780
Instability index59.58
Isoelectric point10.78
Molecular weight60743.18
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10762
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     109.80|      20|      20|     111|     130|       1
---------------------------------------------------------------------------
  111-  127 (28.83/11.11)	......RPGRDRDR..DRKRRTADR
  128-  146 (24.96/ 8.55)	DRDsrkRK.RSRSR..DRH.R..DK
  147-  165 (23.91/ 7.86)	DKD......KDRDRiaRRARARAGR
  166-  185 (32.11/13.29)	TTK...SRSRSRSR..GGKRRHRHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     200.61|      51|      52|     259|     309|       2
---------------------------------------------------------------------------
  188-  229 (60.72/23.58)	......DHAIADRDRNRDRDRKRDRGK.....RRRSKRDS..CAKQL.KRLRTK.LA
  259-  309 (83.17/34.45)	SSMA..DDAIANQPDVAAAAAPRQSGPACLIISSRSAVEF..ITAGI.RYLLTS.LA
  312-  363 (56.72/21.64)	SWLTtvNNDNEDQP..TDAIYPRAR..AVLLLSN.AALLFgyLTEQVdRHRLEHvLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.87|      36|     455|       7|      57|       3
---------------------------------------------------------------------------
    7-   57 (53.76/53.10)	CYPIKSGEAYAYeADVPEHTSGS.VFPKLPTGrdvisllrarsrseISLKFA
  465-  501 (66.11/35.81)	CALTTSGHVFCF.ACIHSHLAGNgSAGKCPTG..............PKLKFA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10762 with Med10 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) VRVPSIIARPGRDRDRDRKRRTADRDRDSRKRKRSRSRDRHRDKDKDKDRDRIARRARARAGRTTKSRSRSRSRGGKRRHRHRSRDHAIADRDRNRDRDRKRDRGKRRRSKRDSCAKQLKRLRTKLARRKGSSRKSRSSSKAQAESEGRSYGSANDSSMADDAIANQPDVAAA
103
275










Molecular Recognition Features






MoRF SequenceStartStop




NANANA