<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10760

Description Uncharacterized protein
SequenceRCNKPGHVEKACRTKQKQFSGNQPPHSKKKFEPSRATKPLSATRTRAIREPLKAFGKYARRSADVTIFDELEILIHPEGVLPVLSFLKDHHAGQFVNLSDICCVDVPSRQFRFRTYTDELTPLESCCSVFQAANWYEREVWDMFGVYFTNHPDLRRILTDYGFQGHPFRKDFPLVGYNEYRYDDEQKRVVIEPVELAQDFRKFEYSTPWEVFPNYRDADKNMRKEGAPRRELPGQGSHQFRIHHKYFKEVRNSAELYKYSHAISSRRLAAMKFEEIECIHLAMMVSEKLTFIDDFLTISMVFLFGSLVFLVLFSTASTAACSNHSLSSCSPPARHLRLARGRIPGPGVRVHLRRPRLSGTRLRLRWSLLHPHLPAYLRYLGIPESADHRVMSRAAYEVPLVEAMGFQHEFDFIAEGTVFRRGLLKVTVYRVYGQVRPPPWRRVQPGGGVRPWPVLTDGRHGGVGAVRHGQDGRPLVADVAGASEADAPLSSLTSDSMLLDRHLQCGRISPSLVEGVHLLEDDSCCLRPGPPRPAPRRLRDGGGVAEGQRLRGDRVVKQSCGVSPADAGAAEFAAASAATTAAAAARAAPHRRRSGGTVGARRRTPGRTSRTATWLGLAVDGVDGLAEHGDDDVEQQDLHHHDVQHHVHRGHQHRANGVHAVGLITIVYVRPGDVADVAGHEVVEPVLAHDGVEGVAEHAEDDLAGALATFGAGALDGLALGVLQRLRRGGGRWAGGGSELDCGSWSNSGTATKDSQSWQCSTAGPNAQCSTAGPQCPGQPQLVPNAQCSTAGPQCPVPSCPHARAAQLVPNARCSTAGPNARCSTAGPQCPVQHSWSPMPAAQLSPMPGAAQLVPNARAAQLSPMPGAAQLGPNAVQHSWSPMPSAAQLVPNARCSTAGPQCPCSTAGPQCPVQHSWSQCPSHSWSPHVQHSWSHMPQCSPVVPMPVQHSWSPMPGAAAQPASPMPAAQLVPSTASHMEGDAEAEHEHEQNEQEGQEVLLHHERHHLELRAEALQHHRYVEQAHPVHQAGGGEQHQRPVALERVVHCAVVDPQGEGGEAAGDGGDVDDVPAVQEVVLDGLLPGAGDHLVDLLDQEAQQGQVADDSPRRRRRGPSEHDHEGQQQHEADVRASRACGTSRRGSVEPQQLRQRAQPRPRLLLLLLGCFCCFRPPAAAPRPARWSLRCASHAPAAAVAFPDDSLMAAGPAGQHTGSAESGAYRDSRAGYSSGTKPQAMASLDQRSLVSVLAAKEKKSLYHIRFSASLWTAGCTQLNLQSCTQLKLQSATHKLILQSTSSRLHPARLPASSPARMSMMTKLLGFALAASSKHAVAAEVSQRQHDQLHGQAVVRCHVDILACLRGACMAMRLQRPRCRAGRPRLRRVLASSSACGMDVEESLLAQEVGARRRTAAGQHAPDRQGLHRGPRMAFRRGGRVVLASDVRPAPTHCSLPELCELRYQAACSFRLADPAFIIEAVARTPGPWMPSLRVAQALVHHNSGPQHPELHHLLQQRLILGPTKMCLRKFVGDLPYHAAADDLVRPGPRHAGLQHNLNETRSSPRCHSFVAEVVLELVSTVRSSRRNCWPCRIASSSLMQLPPLLSTGHHPLAHTLQDRRVLFSLLQSPPAVPHLQFPSRPSPVRPHLLRQHDVNGCSLLNVVEVQPGAGAQHGQEQLGVAQVGGNVQRREAPGPPCRLHRCGLCDSSSWAARTFSSRQARWMGRSPCWSKVPQLAPWSSSRCRNRSSLRILTAACTVDFDLVLAPPLALAPSSSSSCSASSDFRANARSSCCLAILRLRFQLSLKGSHVAADEDAQHIAAVVGCRLVQESPAQAAVQLRVRRHAARCQQLAQQGRRFVGAGQAAHAARGRRPWTGGRSGA
Length1874
PositionHead
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.05
Grand average of hydropathy-0.396
Instability index61.48
Isoelectric point9.28
Molecular weight203861.95
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
NADH dehydrogenase (ubiquinone) activity	GO:0008137	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10760
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     210.37|      26|      33|     784|     810|       1
---------------------------------------------------------------------------
  767-  782 (31.56/ 9.35)	..A.QCS.TAGPQC.P..G..QP.....QL..
  784-  808 (50.89/22.82)	PNA.QCS.TAGPQC.PVPS..CPHArAAQL..
  821-  844 (35.72/11.56)	..A.RCS.TAGPQC.PVQHswSPMP.AAQL..
  873-  890 (28.70/ 7.83)	PNAvQHS.WS.P....MPS.......AAQLV.
  927-  948 (28.39/ 7.66)	PHV.QHSwSHMPQCsPVVP..MPV.......Q
  953-  972 (35.11/11.24)	P.M.PGA.AAQPAS.PMPA........AQLVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.14|      11|      88|     810|     820|       3
---------------------------------------------------------------------------
  810-  820 (27.08/12.49)	PNARCSTAGPN
  891-  901 (27.06/12.48)	PNARCSTAGPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     299.23|      84|      94|    1416|    1509|       4
---------------------------------------------------------------------------
 1143- 1185 (42.55/12.46)	EPQQLRQRAQPRPRLlllllgCFCCFRPPAA......APRP..ARW..SLRCA.....................................................................................................................................................................................................................................................................................................
 1416- 1449 (40.72/11.29)	..........................................................................shapaaavafpddslmaagpagqhtgsaesgayrdsragyssgtkpqamasldqrslvsvlaakekkslyhirfsaslwtagctqlnlqsctqlklqsathklilqstssrlhparlpassparmsmmtkllgfalaasskhavaaevsqrqhdqlhgqavvrchvdilaclrgacmamrlqrprcragrprlrrvlasssacgmdveesllaqevgarrrtaagqhapdRQGLHRGP.RMAFRR.GGRV...VLASD.VR..PAPTHCSLP
 1450- 1547 (118.61/69.67)	ELCELRYQAACSFRL......ADPAFIIEAV......ARTP..GPWmPSLRVAQAlvhhnSGPQHPEL....HH....................................................................................................................................................................................................................................llQQRLILGPtKMCLRKfVGDLpyhAAADDlVR..PGPRHAGLQ
 1549- 1631 (97.34/42.48)	NLNETRSSPRCH............SFVAEVVlelvstVRSSrrNCW.PC.RIASS.....SLMQLPPLlstgHH.............................................................................................................................................................................................................................................P..LAHTL.QDRR...VLFSL.LQspPAVPHLQFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.61|      27|      93|     433|     459|       5
---------------------------------------------------------------------------
  331-  361 (24.71/ 6.94)	.....PPARHLRlargriPGPGVRvhlRRPRLSGTR
  433-  459 (56.63/28.60)	GQVRPPPWRRVQ......PGGGVR...PWPVLTDGR
  529-  554 (48.28/22.94)	GPPRPAP.RRLR......DGGGVA...EGQRLRGDR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.00|      13|     179|     508|     522|       6
---------------------------------------------------------------------------
  488-  502 (18.46/ 7.38)	PlsSLTSDSMLLDRH
  510-  522 (22.54/ 9.39)	P..SLVEGVHLLEDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.31|      23|      24|     674|     697|       7
---------------------------------------------------------------------------
  633-  662 (28.45/ 9.94)	VeqQDLHHHDVQHHVhRGHqhraNGVHAVG
  674-  696 (40.87/23.72)	V..ADVAGHEVVEPV.LAH....DGVEGVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.90|      30|      33|    1012|    1044|       8
---------------------------------------------------------------------------
 1003- 1030 (24.27/14.85)	..ERHHLEL......................raEALQ.........HHR.....yveQAHPVHQAG
 1031- 1061 (31.89/13.03)	GGEQHQRPVALERV...................................vhcavvdpQGEGGEAAG
 1063- 1119 (27.73/10.28)	GGDVDDVP.AVQEVvldgllpgagdhlvdlldqEAQQgqvaddsprRRR........RGPSEHDHE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.49|      21|      33|     168|     188|       9
---------------------------------------------------------------------------
  168-  188 (40.32/29.06)	FRK.DF..PLVGYNEYRYDDEQKR
  200-  223 (33.17/22.48)	FRKfEYstPWEVFPNYRDADKNMR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.17|      14|      15|     586|     599|      11
---------------------------------------------------------------------------
  586-  599 (25.80/12.01)	RAAPHR.RRSGGTVG
  602-  616 (22.37/ 9.31)	RRTPGRtSRTATWLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.29|      13|      15|     705|     717|      14
---------------------------------------------------------------------------
  705-  717 (22.77/10.52)	GALATF..GAGALDG
  721-  735 (20.52/ 8.72)	GVLQRLrrGGGRWAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     187.85|      63|     444|    1319|    1413|      16
---------------------------------------------------------------------------
 1319- 1413 (82.02/95.61)	FALAASSKHaVAAEvsqrqHDQLHGQAVVRCHVdILACLRGACMAMRLQR..PRCRAgrprlrrvlasssacgmdveeslLAQEvgARRRTAAGQHA
 1794- 1858 (105.83/55.17)	FQLSLKGSH.VAAD.....EDAQHIAAVVGCRL.VQESPAQAAVQLRVRRhaARCQQ.......................LAQQ..GRRFVGAGQAA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10760 with Med18 domain of Kingdom Metazoa
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