<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10759

Description Uncharacterized protein
SequenceMSVFTLEYCYTNIFAIASLKEIHYRRYRIAQPVESAHTCSDPVFSSFAKCQRCGILSAWKRYLPDTGDPSKPYDYGNYEKELWVFWHGGHDPPQLRDSLAHDLTPWSDSSDGGGISYEVRTMLFKAVHNCIERCLTGKGYVRLGQWFVRPLVPGLCLDPAVTQQFSLALNYFLHGESVCAAVDAKLYPPVHSLTKQQCQARTPVILSPHGIAGELTGREWDSQNQIESLVWREFFPHVRTDRGFVEVAVGQHRLWYPVDLLFATQAPLPPEPLSQIELNLAAESSADACLQHLLGCQGSDANGVHQQQQQQRCTCRRRTKPRPALTSAYHNRFFQATERTVDREPAMPTLSPQEPLSVEESEAAAAAASGAASIPTADGVGQQPSLKGLPKSEPISPPAAASVEAAKSQGDGVGLMDDESQQQQTQAAAASALAESSSSRPASVKTPQSQPTGSESQPASAAAAAAAPTPPLPPPPPPPPTSSAQQQQQQQPPPLPASSMPNGQASSVAADSLLEPGLGWLSVVQQSLRKRPLPQLEPWEADLNDSGHDVVSELPEWTSLAAYAKHARLLLPARGILNGPASSANATAAGSVGGSGAASGVALPIDDSASPSGIGSLVGLRSSPSKAGLSADSKSTAVSLKSEDILKVENLQMQSIFEVESPEPLDNANATCEGPGLHGNPSSSGCVIGGTSMASCGGSGTLPASDLCRIYPTPPSLENHIHPSPAPETDQANMLSPAAAAAGHHHHHHHASADCGSGPDLANDDDWSFLTSQRHQGGSLGQLFTAQNPPMPHLSIVYVPELPQTHRPHRAAAAAAGHAGGGHYGIGQQIAATPSSASVTAVGHMPAGTPVTPGSFAAVATPVQCPDARTGGHANFEACNICVCHGDLTGSEAGLYMPGLLDRRPSPCQCGFSASANRALGLGSNIFYEDLCDLLGDRRRLDYRPWPSTYSPAVIDSLLNFVSLTIPLRQFRSPPAQQQQSQSDATNSAVAVVAGAAAAAGAATADPAASSSLHPGHLAQFEDCNEAAKLVLQ
Length1033
PositionMiddle
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.06
Grand average of hydropathy-0.299
Instability index59.72
Isoelectric point5.65
Molecular weight108639.92
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats
>MDP10759
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.74|      13|      15|     476|     488|       1
---------------------------------------------------------------------------
  476-  488 (25.67/ 9.67)	PPPPPTSSAQQQQ
  492-  504 (24.07/ 8.55)	PPPLPASSMPNGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     190.33|      38|      38|     392|     429|       2
---------------------------------------------------------------------------
  316-  360 (41.84/14.21)	RR..RTKPrPALTSAyhnrffQATERTVDREPAMPTLSPQEPLSVEE
  361-  390 (43.65/15.12)	SE....AA.AAAASG......AASIPTADGVG......QQPSLKGLP
  392-  429 (64.48/25.58)	SE..PISP.PAAASV......EAAKSQGDGVGLMDDESQQQQTQAAA
  431-  465 (40.36/13.46)	SAlaESSS.SRPASV......KTPQSQPT..G...SESQPASAAAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     405.41|      72|      72|     678|     749|       3
---------------------------------------------------------------------------
  609-  676 (47.62/17.40)	.ASPSGIGSLVGlrsspskaGLSADSKSTA.VSLKSEDILKV........EN.LQmqsifevE...SPEP.LDNAN.....ATCEGPG....
  678-  749 (132.96/62.70)	HGNPSSSGCVIG........GTSMASCGGS.GTLPASDLCRIYP.TPPSLENHIH.......P...SPAPETDQANMLSPAAAAAGHHHHHH
  762-  823 (91.26/40.56)	ANDDDWSFL............TSQRHQGGSlGQLFTAQ....NP.PMPHL.SIVY.......V...PELPQTHRPH..RAAAAAAGHAGGGH
  827-  888 (78.07/33.57)	......GQQIAA........TPSSASVTAV.GHMPAGT.....PvTPGSFAAVAT.......P...VQCPDARTGGHANFEACNICVCHGDL
  902-  953 (55.51/21.59)	DRRPSPCQCGFS........ASANRALGLG.SNIFYEDLCDLLG.DRRRLDYRPW.......PstySPA.......................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.52|      14|      15|     554|     567|       6
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  536-  549 (23.02/11.97)	LEPWEADLNDSGHD
  554-  567 (24.07/12.89)	LPEWTSLAAYAKHA
  571-  584 (21.42/10.57)	LPARGILNGPASSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.06|      21|     402|     588|     608|      12
---------------------------------------------------------------------------
  588-  608 (36.34/19.50)	AAGSVGGSGAASGVAL..PIDDS
  989- 1011 (28.72/13.68)	AVAVVAGAAAAAGAATadPAASS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10759 with Med13 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PTPPSLENHIHPSPAPETDQANMLSPAAAAAGHHHHHHHASADCGSGPDLANDDDWSFLTSQRHQ
2) TSAYHNRFFQATERTVDREPAMPTLSPQEPLSVEESEAAAAAASGAASIPTADGVGQQPSLKGLPKSEPISPPAAASVEAAKSQGDGVGLMDDESQQQQTQAAAASALAESSSSRPASVKTPQSQPTGSESQPASAAAAAAAPTPPLPPPPPPPPTSSAQQQQQQQPPPLPASSMPNGQASSVAADS
712
326
776
512










Molecular Recognition Features






MoRF SequenceStartStop




NANANA