<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10751

Description Uncharacterized protein
SequenceYECVLELLRYPDIDHNLTDGFGLTPLELCQRSEENFPTREHQQSTASLSVPVHLVDGSLHLMILPYRDATTVRQLHLRIMGSLGLTDPRDNLFTLWVCSQNLRLQLKPMHKPVQLMRDWRSKTVPLFTSANPMKEDPKLFLRRNALHAQCTIDGRRVKAFLQSEQNLAGVLPEPSRRVSRLPAGLTSAVAKRYSSSGLRRELEALSLSECHTNFSPSAADWPCLTPYSLLANCQLCLASLVFIGVNDIGLHLLGDPSKRFLYSFHYPNFNWSEIARRHSGSSRHTKSGETTPMRLLSPASYGGPPDGAAGRGELAGGQSVQCAGHSAPDAQPSPFPGVGGANRTGAAAGNQAPGGVDHARFFAEQITRTAQTIVALIDSLPGPRPTEPIRIRMAELEEENHRLGRHLIEVVDQLEARLRRVRACLTDIAQVQLRCGAMESALLLHQETARSCTAPNAAPEFVDQPPSPSSSSKSSSKPAAARRIVRGHPAGLVIGPLPSEHRILDELRHAPRFQAAAAPQTSARKSGVAPPEKNGFPPETLASSLMTAGRKRPAGQPDKSWTRIGDGDEEAEAAPAEDAQAAAERRQQAALEMQGARLHDAEMSGWRRPSGWAAAPSGSSRCCCSTESSWSWSSVSARRRKLRNGKRRRRKEKDKKKKSKKKRSRKSSSSSSDSSSGPSRVPFNRDTDMVVKGLDFEGRHGQQVQSWRSKVPVVF
Length715
PositionMiddle
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.05
Grand average of hydropathy-0.560
Instability index67.32
Isoelectric point9.77
Molecular weight78396.89
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10751
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     116.65|      28|      31|     298|     325|       1
---------------------------------------------------------------------------
  298-  325 (54.19/33.02)	PASYGGP.PD.G......AAGR.GELAGGQSVQCAGH
  328-  358 (39.91/22.07)	PDAQPSPfPGvG......GANRtGAAAGNQAPGGVDH
  531-  555 (22.55/ 8.76)	PEKNGFP.PE.TlasslmTAGR.KRPAG.........
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     382.85|     126|     240|     156|     288|       2
---------------------------------------------------------------------------
  156-  288 (199.79/135.23)	RVK.AFLQSEQNLAG.....VLPEPSRRVSRLPAGLTSAVAKRYSSSGLRRE..LEALSLSECHT.NFSPSAADWPcLTPYSLLANCQLCLASLVFIGVNDIGLhLLGD.PSK.RFLYSF.HYPNFnwsEIARRHSGSSRhtKSG
  390-  527 (183.06/103.39)	RIRmAELEEENHRLGrhlieVVDQLEARLRRVRACLTDIAQVQLRCGAMESAllLHQETARSCTApNAAPEFVDQP.PSPSSSSKSSSKPAAARRIVRGHPAGL.VIGPlPSEhRILDELrHAPRF...QAAAAPQTSAR..KSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.91|      13|     585|     114|     127|       3
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  114-  127 (22.73/17.88)	QLMRDWRSKtVPL.F
  702-  715 (22.18/12.15)	QQVQSWRSK.VPVvF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     141.04|      42|      48|     594|     639|       4
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  594-  639 (71.24/44.56)	QGARLHDAEMSGWRRPSGWAAAPSGSSrcccSTESSWSWSSVSARR
  644-  685 (69.80/33.77)	NGKRRRRKEKDKKKKSKKKRSRKSSSS....SSDSSSGPSRVPFNR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10751 with Med21 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ILDELRHAPRFQAAAAPQTSARKSGVAPPEKNGFPPETLASSLMTAGRKRPAGQPDKSWTRIGDGDEEAEAAPAEDAQAAAERRQQAALEMQGARLHDAEMSGWRRPSGWAAAPSGS
2) RHSGSSRHTKSGETTPMRLLSPASYGGPPDGAAGRGELAGGQSVQCAGHSAPDAQPSPFPGVGGANRTGAAAGNQAPGGVDHARF
3) SVSARRRKLRNGKRRRRKEKDKKKKSKKKRSRKSSSSSSDSSSGPSRVPFNRDTDMVVKGLDFEGRHGQQ
4) TAPNAAPEFVDQPPSPSSSSKSSSKPAAARRIVRGHPAGL
503
277
634
453
619
361
703
492










Molecular Recognition Features






MoRF SequenceStartStop




1) KRRRRKEKDKKKKSKKKRSRKSS
2) SRVPFNR
3) WTRIGD
646
679
561
668
685
566