<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10740

Description Uncharacterized protein
SequenceMVEDLATIISLINNATDLDKKMVTSAQQLSQAASMLESFPMTRAQLETTRLGKLLNEVRRFTDSTDLQRRLRRLLKGWQPLVSANDPNYSVVVNGNGSNPVPAPPAQVAAVQPAVDEATVPVANAASVDGESGSVGSVGSSASVIVPPPAATPSSASVRIRKRAAANAASGDTASSASAVPAKLAKCLERRTAWHLSSRPPGSSSSSRLQAAPLENAAELTVPPLPPPLENAAELTVPPLPPPPQRLPSPAPRPPRCPRTANRLCCTNS
Length269
PositionUnknown
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.02
Grand average of hydropathy-0.244
Instability index61.04
Isoelectric point9.68
Molecular weight28015.51
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10740
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.21|      34|      42|      90|     129|       1
---------------------------------------------------------------------------
   90-  122 (32.04/17.17)	...............................SV.VVNGNGSN.................PVPaPPAQVAAvqpavDEATVPV
  123-  160 (44.84/13.74)	ANAASVD....................gesgSVgSVGSSASV.................IVP.PPAA.TP.....SSASVRI
  166-  238 (30.34/ 7.21)	ANAASGDtassasavpaklakclerrtawhlSS.RPPGSSSSsrlqaaplenaaeltvpPLP.PPLENAA......ELTVP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.75|      17|      17|      50|      66|       2
---------------------------------------------------------------------------
   50-   66 (28.02/18.48)	RLGKLLNEVRRFTDSTD
   70-   86 (29.72/19.98)	RLRRLLKGWQPLVSAND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.68|      15|      15|      13|      27|       4
---------------------------------------------------------------------------
   13-   27 (24.73/16.99)	NNATDLDKKMVTSAQ
   31-   45 (25.94/18.14)	QAASMLESFPMTRAQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10740 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSVGSSASVIVPPPAATPSSASVRIRKRAAANAASGDTASSASAVPA
2) RRTAWHLSSRPPGSSSSSRLQAAPLENAAELTVPPLPPPLENAAELTVPPLPPPPQRLPSPAPRPPRCPRTANRL
136
190
182
264










Molecular Recognition Features






MoRF SequenceStartStop




1) AKLAKCLERRTAWHL
2) ASVRIRKRAAA
3) RLRRLLKGW
182
156
70
196
166
78