<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10739

Description Uncharacterized protein
SequenceQLQMSDSSRISAFPLPPMKYVNCYTDEQVHSGTAPPPPRPLDSSYAMFGMPCTKEDAVIHSLESQGIRRLYPALYDHKRELKKLNFSILANYLDLMDIVVKCPDSQERLQKLEHLKTLFINVHHLINEYRPLQARDTLIEMLSLQSSVTRQAVDTASRYLARADAVVGRAAAASVGGDEDEPMRGADEAAGGEISRALLNDIDRLSAELSELTAAAAELDDAESAGFDLFASRGDNGNEAVGDSATDDVELEADSDETSEDDDEPDDADEAGEAVVNLPAGHQAAVGFSTVNDAASGSLAQAPAAEAAVGASDEAPSPSAPPPPPQMPPPPYSPEEGATNASNCSSRHLRGLVRAALEADEANGGVGGSEVVARYLDARRQLLAAHSDATEDSLKQLAASLLEKVNSRLLSLGVQLPDESNEADEPTVAATELFRLPDGVRLFFVASDGRIRHGGSNSSLSLFVFDDAATASEAEQSQSAQPPAFITVGSHWRCPLIPGVTPVLASASGALIFPDLEAQDEASSVGVMLPEGLDTESRFLLLDLLACLSRLGIERQPEAPEKPPPYAPTPTPTPAVAPADADADQKPARRHTSDHLVTGIGWTAARMCEGAVAGGRLAGDLLTRARLAAQKRMRPAAAGSSAGSAAGSAAGNSNESANLDHVTTGVRLLRQGSAVGVRVSRRLVSGLVSGAGFLASRVVYPHAVAPALNAVGVSTSGRGSRSRLAGAARVAGAALSGASDVWESLGVAGSQLATCAADNGQALATHRWGDRAGAVTGDALHAGGNVARIAWATNALGVRAALKVVAMETGKEAVGRMAESDGAKAASAASGSAPSTGAKR
Length840
PositionMiddle
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.04
Grand average of hydropathy-0.199
Instability index42.79
Isoelectric point4.86
Molecular weight86958.65
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10739
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     223.86|      44|      44|     205|     248|       1
---------------------------------------------------------------------------
  170-  201 (24.17/ 6.97)	.........................AA....AASVGGDEdEPMRG..ADEAAGGEISrallND
  205-  248 (70.05/34.44)	LSAE..............LSELTAAAAELDDAESAGFDL.FASRGDNGNEAVGDSAT....DD
  251-  293 (63.47/30.50)	LEAD..............SDETSEDDDEPDDADEAG.EA.VVNLPAGHQAAVGFSTV....ND
  345-  374 (37.14/14.74)	SSRH..............LRGLVRAALEADEANG..........GVGGSEVVAR.........
  376-  423 (29.02/ 9.88)	LDARrqllaahsdatedsLKQL..AASLLEKVNSRLLSL.GVQLPDESNEA............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     227.94|      46|      46|     601|     646|       2
---------------------------------------------------------------------------
  601-  639 (57.57/26.17)	.............GW.TAARMC.EGA.......VA......GGRLAGDLLT.......RARLAAQKRM.RPAA.AG
  640-  686 (58.12/26.50)	SSAGSAA......GS.AAGNSN.ESA.......NL......DHVTTGVRLL.......RQGSAVGVRVsRRLV.SG
  689-  737 (40.03/15.80)	SGAG...........fLASRVVyPHA.......VApalnavGVSTSGR.GS.......RSRLAGAARV.AGAAlSG
  738-  769 (28.83/ 9.18)	AS........................dvweslgVA......GSQLATCAAD.......NGQALATHRW.......G
  770-  829 (43.39/17.79)	DRAGAVTgdalhaGG.NVARIA.WAT.......NA.....lGVRAALKVVAmetgkeaVGRMAESDGA.KAAS.AA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     127.49|      26|     284|      26|      56|       3
---------------------------------------------------------------------------
   26-   56 (45.68/28.02)	DEQvHSGTAPPPPRPldssYAMFGMPCTKED
  313-  336 (53.41/22.32)	DEA.PSPSAPPPP.P.....QMPPPPYSPEE
  557-  574 (28.39/ 8.65)	......PEAPEKPPP....YAPTPTP.TP..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10739 with Med7 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IERQPEAPEKPPPYAPTPTPTPAVAPADADADQKPARRHTSDH
2) RMRPAAAGSSAGSAAGSAAGNSNESANLDHVT
3) SAGFDLFASRGDNGNEAVGDSATDDVELEADSDETSEDDDEPDDADEAGEAVVNLPAGHQAAVGFSTVNDAASGSLAQAPAAEAAVGASDEAPSPSAPPPPPQMPPPPYSPEEGATNASNCSSR
553
632
224
595
663
347










Molecular Recognition Features






MoRF SequenceStartStop




NANANA