<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10734

Description Uncharacterized protein
SequenceMVEDLATIISLINNATDLDKKMVTSAQQLSQAASMLESFPMTRAQLETTRLGKLLNEVRRFTDSTDLQRRLRRLLKGWQPLVSANDPNYSVVVNGNGSNPVPAPPAQVAAVQPAVDEATVPVANAASVDGESGSVGSVGSSASVIVPPPAATPSSASVRIRKRAAANAASGDTASSASAVPAKLAKVRSTAELLTGREGLRLETLARILNNEVPRETDGLAPEQPAARQQQQQQTAGGSTRKRRRVDSPASAASSSAAALASASAAALPPDGESALLHKFLESAVSHPVVEEAAE
Length295
PositionUnknown
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.02
Grand average of hydropathy-0.227
Instability index55.08
Isoelectric point8.03
Molecular weight30506.83
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10734
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.39|      40|      41|      90|     129|       1
---------------------------------------------------------------------------
   90-  122 (48.93/20.15)	...........SVVVNGNG.SNPVPAPPAQVAAVQPAVDEAT....VPV
  123-  160 (48.27/19.79)	ANAASVDgesgSVGSVGSS.ASVIVPPPAA....TPS..SAS....VRI
  166-  202 (35.19/12.67)	ANAASGD............tASSASAVPAKLAKVRSTAELLTgregLRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.75|      17|      17|      50|      66|       2
---------------------------------------------------------------------------
   50-   66 (28.02/17.48)	RLGKLLNEVRRFTDSTD
   70-   86 (29.72/18.90)	RLRRLLKGWQPLVSAND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.67|      17|      17|      11|      27|       5
---------------------------------------------------------------------------
   11-   27 (27.72/22.14)	LINNATDLDKKMVTSAQ
   29-   45 (28.95/23.44)	LSQAASMLESFPMTRAQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10734 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSVGSSASVIVPPPAATPSSASVRIRKRAAANAASGDTASSASAVPA
2) TLARILNNEVPRETDGLAPEQPAARQQQQQQTAGGSTRKRRRVDSPASAASSSAAALASASAAAL
136
204
182
268










Molecular Recognition Features






MoRF SequenceStartStop




1) AAALASASA
2) ASVRIRKRAAANAA
3) RKRRRVDS
4) SALLHKFLE
257
156
241
274
265
169
248
282