<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10730

Description Uncharacterized protein
SequenceDSKMKMMAELQLTAVNDARSRSTICRDIQQWEENLERLHIELFRYKCYMASLLGSELPNPKNTLAGASKTSKLALSRLGAFSLSAFHALVCARAPLTTATLHHRARASGRHGADGGPAAAAATIGRPVDKRNGHLQQQQQQQQQQQQQRQPHHQSSVLMTAQSSASMPRQPQQPLLPASQQQQQQQQQQQQQQQSQLARAKSELLVQQRSSTSGVTDNTNTSSERSSRAAAAAAPATVALSTTGGGPATSSQQDSLIGIRLPSGQTLMANVQEGMTVQEILEMICRESDLDPKQHYIRLRLSEHGIDIIPDNYTVFENQVTVSSFELNARMFIKFIMSTEKKQYLKIFIRSSNLIMNNFYSRKGLTFNL
Length369
PositionTail
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.05
Grand average of hydropathy-0.570
Instability index69.11
Isoelectric point9.77
Molecular weight40927.76
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:InterPro

GO - Biological Process
activation of GTPase activity	GO:0090630	IEA:InterPro
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10730
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.19|      31|      45|     136|     166|       1
---------------------------------------------------------------------------
  136-  166 (59.63/27.19)	QQQQQQQQQQQQQRQ...PHHQSSVLMTAQSSAS
  180-  213 (51.56/22.63)	QQQQQQQQQQQQQQQsqlARAKSELLVQQRSSTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.82|      17|     109|     108|     124|       2
---------------------------------------------------------------------------
  108-  124 (31.32/21.36)	SGRHGADGGPAAAAATI
  222-  238 (26.50/16.98)	SSERSSRAAAAAAPATV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10730 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATLHHRARASGRHGADGGPAAAAATIGRPVDKRNGHLQQQQQQQQQQQQQRQPHHQSSVLMTAQSSASMPRQPQQPLLPASQQQQQQQQQQQQQQQSQLARAKSELLVQQRSSTSGVTDNTNTSSERSSRAAAAAAPATVALSTTGGGPATSSQQDSLI
99
257










Molecular Recognition Features






MoRF SequenceStartStop




NANANA