<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10729

Description Uncharacterized protein
SequenceMHSPGIRPSPRAAQAAAAAAAAAASVAGPSGVSSSSRGRTWIDADFCREIGRQREKVEDVFEFEGCKVGRGTYGHVFKSKKKSGNDQKEYALKQIEGSGLSMSACREIALLRELCHPNVIALQRVFLSHDTRKVWLLFDYAEHDLWHIIKHHRSAKASKTKVFVPRNMVKSLMHQILNGIHYLHSNWVLHRDLKPANILVMGNGPERGRVKIADMGFARLFNQPLKPLAELDPVVVTFWYRAPELLLGARHYTKAIDLWAIGCIMAELLTYEPIFHCRQEDIKTSQPYHHDQLDRIFSVMGYPKEQDWRDIVHMPEYSRMTRNFKGGNYAKCSLEAFMERKYGITSNAVEFKLLSKLLTMDPLKRITAKDAMEDRYFLEDPKPSHDVFEGMEIPYSKREFISDDDADDKEKLLQRQQHLQAGQAGSSGMSQISSQQQSSSMMSGEPAAKRGRMQIPAQHPDHHHHHHQQQQQQGFLQPAHSSQQQKRFQQNRFGQQPNFGVGGQKYN
Length507
PositionKinase
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.09
Grand average of hydropathy-0.629
Instability index46.87
Isoelectric point9.25
Molecular weight57806.16
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10729
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.91|      24|      47|     414|     437|       1
---------------------------------------------------------------------------
  414-  437 (41.96/23.82)	QRQQHLQAGQ.AGSSGMSQISSQQQ
  440-  460 (22.77/ 9.64)	....SMMSGEpAAKRGRMQIPAQHP
  463-  485 (42.17/23.98)	HHHHHQQQQQ.QGFLQPAH.SSQQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10729 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) REFISDDDADDKEKLLQRQQHLQAGQAGSSGMSQISSQQQSSSMMSGEPAAKRGRMQIPAQHPDHHHHHHQQQQQQGFLQPAHSSQQQKRFQQNRFGQQPNFGVGGQKYN
398
507










Molecular Recognition Features






MoRF SequenceStartStop




1) RGRMQIP
2) RPSPRAAQAAAAAAAA
3) VGGQKY
450
7
501
456
22
506