<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10728

Description Uncharacterized protein
SequenceMSVFTLEYCYTNIFAIASLKEIHYRRYRIAQPVESAHTCSDPVFSSFAKCQRCGILSAWKRYLPDTGDPSKPYDYGNYEKELWVFWHGGHDPPQLRDSLAHDLTPWSDSSDGGGISYEVRTMLFKAVHNCIERCLTGKGYVRLGQWFVRPLVPGLCLDPAVTQQFSLALNYFLHGESVCAAVDAKLYPPVHSLTKQQCQARTPVILSPHGIAGELTGREWDSQNQIESLVWREFFPHVRTDRGFVEVAVGQHRLWYPVDLLFATQAPLPPEPLSQIELNLAAESSADACLQHLLGCQGSDANGVHQQQQQQRCTCRRRTKPRPALTSAYHNRFFQATERTVDREPAMPTLSPQEPLSVEESEAAAAAASGAASIPTADGVGQQPSLKGLPKSEPISPPAAASVEAAKSQGDGVGLMDDESQQQQTQAAAASALAESSSSRPASVKTPQSQPTGSESQPASAAAAAAAPTPPLPPPPPPPPTSSAQQQQQQQPPPLPASSMPNGQASSVAADSLLEPGLGWLSVVQQSLRKRPLPQLEPWEADLNDSGHDVVSELPEWTSLAAYAKHARLLLPARGILNGPASSANATAAGSVGGSGAASGVALPIDDSASPSGIGSLVGLRSSPSKAGLSADSKSTAVSLKSEDILKVENLQMQSIFEVESPEPLDNANAACEGPGLHGNPSSSGCVIGGTSMASCGGSGTLPASDLCRIYPTPPSLENHIHPSPAPETDQANMLSPAAAAAGHHHHHHHASADCGSGPDLANDDDWSFLTSQRHQGGSLGQLFTAQNPPMPHLSIVYVPELPQTHRPHRAAAAAAGHAGGGHYGIGQQIAATPSSASVTAVGHMPAGTPVTPGSFAAVATPASVRTPGQAGTPCGSIVGEQLDQSQLSTGHQSIQASQAQPVEALRLNLLLSDSLLCLCRDQNFEACNICVCHGDLTGSEAGLYMPGLLDRRPSPCQCGFSASANRALGLGSNIFYEDLCDLLGDRRRLDYRPWPSTYSPAVIDSLLNFVSLTIPLRQFRSPPAQQQQSQSDATNSAVAVVAGAAAAAGAATADPAASSSLHPGHLAQFEDCNEAAKLVLQ
Length1082
PositionMiddle
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.06
Grand average of hydropathy-0.284
Instability index59.59
Isoelectric point5.59
Molecular weight113789.69
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10728
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.74|      13|      15|     476|     488|       1
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  476-  488 (25.67/ 9.11)	PPPPPTSSAQQQQ
  492-  504 (24.07/ 8.05)	PPPLPASSMPNGQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     404.25|      72|      72|     678|     749|       2
---------------------------------------------------------------------------
  609-  676 (48.61/15.00)	.ASPSGIG..........................SLVGlrsspskaGLSADSKS...TA.VSLKSEDILKV........EN.LQmqsifevESPEP.LDNAN.....AACEGPG....
  678-  749 (135.98/54.24)	HGNPSSSG..........................CVIG........GTSMASCG...GS.GTLPASDLCRIYP.TPPSLENHIH.......PSPAPETDQANMLSPAAAAAGHHHHHH
  762-  818 (82.73/30.32)	ANDDDWSF..........................L............TSQRHQG...GSlGQLFTAQ.......NPP.MP.HLS.......IVYVPELPQTHRPHRAAAAAA....GH
  821-  886 (86.33/31.94)	GGHYGIGQ..........................QIAA........TPSSASVT...AV.GHMPAGT.....PvTPGSFAAVAT.......PASVRTPGQAG..TPCGSIVGEQLDQS
  889-  970 (50.59/15.89)	.....STGhqsiqasqaqpvealrlnlllsdsllCLCR........DQNFEACNicvCH.GDLTGSE.AGLY...MPGLLDR.R.......PSPC....QCGFSASANRALG......
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     226.17|      49|      84|     346|     394|       4
---------------------------------------------------------------------------
  346-  386 (62.97/23.26)	........AMPTL..SPQEPLS.VEESE.AAAAAASGAASIPTA........................................DGVGQQPSL
  387-  414 (32.69/ 8.55)	KGLPKSEP....................iSPPAAASVEAAKSQG........................................DGVG.....
  416-  443 (33.25/ 8.82)	.........MDDE..SQQ......QQTQ.AAAASALAESS...............................................SSRPAS
  444-  519 (36.80/10.55)	VKTPQSQPTG.....SESQPAS.......AAAAAAAPTPPLPPPppppptssaqqqqqqqppplpassmpngqassvaadsllePGLG.....
  531-  577 (60.45/22.04)	RPLPQLEPWEADLndSGHDVVSeLPEWT.SLAAYAKHARLLLPA........................................RGI.....L
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.08|      21|     112|     179|     202|       8
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  179-  202 (34.23/25.11)	CAAVDAKlypPVHSLTKQQ...CQART
  296-  319 (36.86/18.65)	CQGSDAN...GVHQQQQQQrctCRRRT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.37|      21|     435|     580|     602|      10
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  582-  602 (35.04/22.32)	SSANATAAGSVGGSGAASGVA
 1032- 1052 (33.33/13.98)	SDATNSAVAVVAGAAAAAGAA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10728 with Med13 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PTPPSLENHIHPSPAPETDQANMLSPAAAAAGHHHHHHHASADCGSGPDLANDDDWSFLTSQRHQGGSLGQLFTA
2) TSAYHNRFFQATERTVDREPAMPTLSPQEPLSVEESEAAAAAASGAASIPTADGVGQQPSLKGLPKSEPISPPAAASVEAAKSQGDGVGLMDDESQQQQTQAAAASALAESSSSRPASVKTPQSQPTGSESQPASAAAAAAAPTPPLPPPPPPPPTSSAQQQQQQQPPPLPASSMPNGQASSVAADS
712
326
786
512










Molecular Recognition Features






MoRF SequenceStartStop




NANANA