<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10725

Description Uncharacterized protein
SequenceMNPAGVQISAECLPEYTVERINPDGSEVHEKPPTASEAFCQLVSKIKFQQWDEDLEEFVSEVEPTIGSADEQLDDSNLSTGGGQQQAASLGPANAESASYWQNIRLSIAAALDETTALMDLLIALRQRPQALTLEPMQRDVEKYEQRIQLVVQGKKKCVQAAAEVLEKGRGSNQMLQQEVIGNFELQQIAQCWKLRRVANTISGDLSLRSAGSRYPDSGGFELRTAKDSSFEVLLPGHLYGQACVQVTLRTSSGESLFPQPAATELPRVSLCNSQRLLLAQELYNTICCECVQAGIRAGPDAVELPLAPGLCANVSLYKVVGPEIQQQQSSPPG
Length334
PositionHead
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.05
Grand average of hydropathy-0.292
Instability index47.94
Isoelectric point4.69
Molecular weight36317.55
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP10725
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.62|      33|      42|     208|     240|       1
---------------------------------------------------------------------------
  208-  240 (59.40/33.06)	LR..SAGSRYPDSGGFEL.RTAKDSSFEVLLPGHLY
  249-  284 (48.22/25.74)	LRtsSGESLFPQPAATELpRVSLCNSQRLLLAQELY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.49|      30|     137|     157|     188|       2
---------------------------------------------------------------------------
  157-  188 (45.06/36.61)	KCVQA.......AAEV.LEKGRGSNQMLQQeVIGNfELQQ
  290-  327 (43.43/25.89)	ECVQAgiragpdAVELpLAPGLCANVSLYK.VVGP.EIQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.60|      23|      42|      84|     106|       3
---------------------------------------------------------------------------
   84-  106 (40.34/27.97)	QQQAASLGPANAESASYWQNIRL
  128-  150 (40.26/27.90)	RPQALTLEPMQRDVEKYEQRIQL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP10725 with Med17 domain of Kingdom Metazoa

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