<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10722

Description Uncharacterized protein
SequenceMVEDLATIISLINNATDLDKKMVTSAQQLSQAASMLESFPMTRAHLETTRLGKLLNEVRRFTDSTDLQRRLRRLLKGWQPLVSANDPNYSVVVNGNGSNPVPAPPAQVVAVQPAVDEATVPVANAASVDGESGSVGSVGSSASAIVPPPAATPSSASVRIRKRAAANAAAGDTASSAPAVPAKLAKVRSTAELLTGREGLRPETLARILNNEVPRETDGLAPEQTAARQQQQQQQQTAGGSTRKRRRLDSPASAASSSAAALASASAAALPPDGESALLHKFLESAVSHP
Length290
PositionUnknown
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.02
Grand average of hydropathy-0.270
Instability index56.89
Isoelectric point9.61
Molecular weight30040.35
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10722
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.92|      15|      18|     192|     206|       2
---------------------------------------------------------------------------
  192-  206 (25.67/11.23)	ELLTGREGLRPETLA
  212-  226 (26.24/11.59)	EVPRETDGLAPEQTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      92.51|      21|      32|     139|     159|       3
---------------------------------------------------------------------------
   95-  121 (27.38/10.55)	GNGSNPVPAPPaqvvAVQPAvdEATVP
  139-  159 (35.89/16.07)	GSSASAIVPPP....AATPS..SASVR
  171-  188 (29.24/11.75)	GDTASS...AP....AVPAK..LAKVR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10722 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSVGSSASAIVPPPAATPSSASVRIRKRAAANAAAGDTASSAPAVPAKLAKVRSTAELLTGREGLRPETLARILNNEVPRETDGLAPEQTAARQQQQQQQQTAGGSTRKRRRLDSPASAASSSAAALASASAAALP
136
271










Molecular Recognition Features






MoRF SequenceStartStop




1) AKLAKV
2) ASVRIRKRAAANAAA
3) ESALLHKFLESAVSH
4) SAAALASASA
5) TRKRRRLDSPASAAS
182
156
275
258
242
187
170
289
267
256