<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10718

Description Uncharacterized protein
SequenceMFSHRVIRQIVPIAGVGNYCMPPAILQHPQPSSVTNVPVNLLASTGALDLKGPLPYARCLQRPHTSLIRAVLTQQGSMDLLLSLLSLHTAPRASKISRCLFLERCLIDTILWTADETEACESDSEMAWADMMWRHLGLYSIHLCRLHLVRFPEMCLGVLEGLQDRRDSLSRSAPHIAWMLFNFLGAQNKNPLVDFAPILRILDALFPGGAPAFDTTLLVWFSLTQKSSAPNERLPRALPPPMQPMMSELMEKFQQMSQSPSYQVPLDPEEFRWFAYVYNAYAPLGQPQVVSPLNSKLVEALKQSDAIAPSYSSLRQLATMSLLAINSLLYNLLSTHADSPVVLDTYARITVLMHHDLNLQPKSVLTEAFTKAGNTGGSRVLAFVFELATYHLNSVEPMQRHLLLQNLVTLAKANRLGLDTELCLYRQAQALLTPALQVTNNHVKKLYVAWICGSDQEELNKYLLLQINHQLIHQQADPDGLLLSDFVQPLFQKCSAACLVPISMQPRLLASPDRISVPSAERQSHQLTGSAELATRLSQRILQEGQCDEAQLSDPSAGCLYWVALSCLRERGGDLPAAQLFPPSGGANGSLSALVSQLRQVYDDTPGGSSSSASLYSHAAIRVALLMDTALARLVQLQPPDSCALLSATLAPFLRHMPAPGTCLISLLSVYDPPAPLRLYLAAALLAPRMEAAADGAYLPSDCLPFFKSLLASPSPPAPAAQASSSDWLSCIGPPEAALNRLSLALSSHGRRGFPQLDWFGHEWPSSCSHAVNCCALQLLLCPVDLPAPVMPPRTAGLSSGFILSSKSKPHSNRQNDGGAAAKRARLEAEQDAFLDADDGGDGEEDDEGGGEESEDADEDEVDKLDWQSAGLLLAQMPARFTTRLVQQPLLALYDQLSGAAPHKALGHELASRPEVCLWFAYLSHAGPGRVAQLPVFFRHSNELVAELYHCLAEVDAACSGRLEHQDALADYFYHIKYMFVGDGVRRVASSVIERLSPSMQSRLRSIAPGHQPDGPADAPNFPA
Length1024
PositionTail
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.07
Grand average of hydropathy-0.025
Instability index59.82
Isoelectric point5.73
Molecular weight111723.78
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10718
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.11|      27|      27|     543|     569|       1
---------------------------------------------------------------------------
  474-  506 (28.42/12.83)	....................................QQADPDGLLLSDfvqPlfqkcSAACLVPISMQP
  507-  567 (32.80/16.18)	RLlaspdrisvpsaerqshqltgsaelatrlsqrilQEGQCDEAQLSD...P.....SAGCLYWVALSC
  655-  669 (26.88/11.66)	RH..................................MPA............P......GTCL..ISLLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     242.58|      61|     151|     582|     647|       2
---------------------------------------------------------------------------
  115-  155 (62.71/26.50)	......................DETEACESDSEMAWADMMWRHLGLYSIHLCRLHLVRFPEMC
  582-  643 (98.50/59.12)	PPSGGANgSLS.ALVSQLRQVYDDTPGGSSSSASLYSHAAIRVALLMDTALARLVQLQPPDSC
  734-  783 (81.37/40.28)	PPEAALN.RLSlALSSHGRRGFPQLDWFGHEWPSSCSHA.........VNCCALQLLLCP...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.11|      30|      73|     316|     345|       3
---------------------------------------------------------------------------
  316-  345 (49.88/28.82)	QLATMSL.LAINS........LLYNLLSTHAD....SPVVLDT
  351-  381 (25.55/11.27)	VLMHHDLnLQPKS........VLTEAF.TKAGntggSRVL...
  386-  420 (35.67/18.57)	ELATYHL....NSvepmqrhlLLQNLVTLAKA....NRLGLDT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.38|      37|     644|     243|     306|       4
---------------------------------------------------------------------------
  191-  228 (59.04/55.88)	PL..VDFAPILRILDALFPGGAPAFDTTL...LVwFSLTQKSS
  265-  306 (56.34/35.96)	PLdpEEFRWFAYVYNAYAPLGQPQVVSPLnskLV.EALKQSDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.20|      25|     211|     677|     706|       5
---------------------------------------------------------------------------
  681-  705 (43.51/31.62)	LAAALLAPRMEAAADGAYLPSDCLP
  786-  810 (44.69/17.68)	LPAPVMPPRTAGLSSGFILSSKSKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.50|      21|      77|     874|     894|       6
---------------------------------------------------------------------------
  874-  894 (37.38/16.31)	LAQMPARFTTRLVQQPLLALY
  952-  972 (37.12/16.15)	LAEVDAACSGRLEHQDALADY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.00|      33|      37|      26|      60|       9
---------------------------------------------------------------------------
   27-   59 (59.63/36.55)	QHPQPSSVTNV.....PVNLLAS.......TGALDLKGPLPYARC
   61-  105 (45.37/25.24)	QRPHTSLIRAVltqqgSMDLLLSllslhtaPRASKISRCLFLERC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10718 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QDAFLDADDGGDGEEDDEGGGEESEDADEDEV
831
862










Molecular Recognition Features






MoRF SequenceStartStop




NANANA