<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10718

Description Uncharacterized protein
SequenceMFSHRVIRQIVPIAGVGNYCMPPAILQHPQPSSVTNVPVNLLASTGALDLKGPLPYARCLQRPHTSLIRAVLTQQGSMDLLLSLLSLHTAPRASKISRCLFLERCLIDTILWTADETEACESDSEMAWADMMWRHLGLYSIHLCRLHLVRFPEMCLGVLEGLQDRRDSLSRSAPHIAWMLFNFLGAQNKNPLVDFAPILRILDALFPGGAPAFDTTLLVWFSLTQKSSAPNERLPRALPPPMQPMMSELMEKFQQMSQSPSYQVPLDPEEFRWFAYVYNAYAPLGQPQVVSPLNSKLVEALKQSDAIAPSYSSLRQLATMSLLAINSLLYNLLSTHADSPVVLDTYARITVLMHHDLNLQPKSVLTEAFTKAGNTGGSRVLAFVFELATYHLNSVEPMQRHLLLQNLVTLAKANRLGLDTELCLYRQAQALLTPALQVTNNHVKKLYVAWICGSDQEELNKYLLLQINHQLIHQQADPDGLLLSDFVQPLFQKCSAACLVPISMQPRLLASPDRISVPSAERQSHQLTGSAELATRLSQRILQEGQCDEAQLSDPSAGCLYWVALSCLRERGGDLPAAQLFPPSGGANGSLSALVSQLRQVYDDTPGGSSSSASLYSHAAIRVALLMDTALARLVQLQPPDSCALLSATLAPFLRHMPAPGTCLISLLSVYDPPAPLRLYLAAALLAPRMEAAADGAYLPSDCLPFFKSLLASPSPPAPAAQASSSDWLSCIGPPEAALNRLSLALSSHGRRGFPQLDWFGHEWPSSCSHAVNCCALQLLLCPVDLPAPVMPPRTAGLSSGFILSSKSKPHSNRQNDGGAAAKRARLEAEQDAFLDADDGGDGEEDDEGGGEESEDADEDEVDKLDWQSAGLLLAQMPARFTTRLVQQPLLALYDQLSGAAPHKALGHELASRPEVCLWFAYLSHAGPGRVAQLPVFFRHSNELVAELYHCLAEVDAACSGRLEHQDALADYFYHIKYMFVGDGVRRVASSVIERLSPSMQSRLRSIAPGHQPDGPADAPNFPA
Length1024
PositionTail
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.07
Grand average of hydropathy-0.025
Instability index59.82
Isoelectric point5.73
Molecular weight111723.78
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10718
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.11|      27|      27|     543|     569|       1
---------------------------------------------------------------------------
  474-  506 (28.42/12.83)	....................................QQADPDGLLLSDfvqPlfqkcSAACLVPISMQP
  507-  567 (32.80/16.18)	RLlaspdrisvpsaerqshqltgsaelatrlsqrilQEGQCDEAQLSD...P.....SAGCLYWVALSC
  655-  669 (26.88/11.66)	RH..................................MPA............P......GTCL..ISLLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     242.58|      61|     151|     582|     647|       2
---------------------------------------------------------------------------
  115-  155 (62.71/26.50)	......................DETEACESDSEMAWADMMWRHLGLYSIHLCRLHLVRFPEMC
  582-  643 (98.50/59.12)	PPSGGANgSLS.ALVSQLRQVYDDTPGGSSSSASLYSHAAIRVALLMDTALARLVQLQPPDSC
  734-  783 (81.37/40.28)	PPEAALN.RLSlALSSHGRRGFPQLDWFGHEWPSSCSHA.........VNCCALQLLLCP...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.11|      30|      73|     316|     345|       3
---------------------------------------------------------------------------
  316-  345 (49.88/28.82)	QLATMSL.LAINS........LLYNLLSTHAD....SPVVLDT
  351-  381 (25.55/11.27)	VLMHHDLnLQPKS........VLTEAF.TKAGntggSRVL...
  386-  420 (35.67/18.57)	ELATYHL....NSvepmqrhlLLQNLVTLAKA....NRLGLDT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.38|      37|     644|     243|     306|       4
---------------------------------------------------------------------------
  191-  228 (59.04/55.88)	PL..VDFAPILRILDALFPGGAPAFDTTL...LVwFSLTQKSS
  265-  306 (56.34/35.96)	PLdpEEFRWFAYVYNAYAPLGQPQVVSPLnskLV.EALKQSDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.20|      25|     211|     677|     706|       5
---------------------------------------------------------------------------
  681-  705 (43.51/31.62)	LAAALLAPRMEAAADGAYLPSDCLP
  786-  810 (44.69/17.68)	LPAPVMPPRTAGLSSGFILSSKSKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.50|      21|      77|     874|     894|       6
---------------------------------------------------------------------------
  874-  894 (37.38/16.31)	LAQMPARFTTRLVQQPLLALY
  952-  972 (37.12/16.15)	LAEVDAACSGRLEHQDALADY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.00|      33|      37|      26|      60|       9
---------------------------------------------------------------------------
   27-   59 (59.63/36.55)	QHPQPSSVTNV.....PVNLLAS.......TGALDLKGPLPYARC
   61-  105 (45.37/25.24)	QRPHTSLIRAVltqqgSMDLLLSllslhtaPRASKISRCLFLERC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10718 with Med23 domain of Kingdom Metazoa
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