<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10715

Description Uncharacterized protein
SequenceEDRKRAVKLYISHVMEEFLDRVHICDELLVSHDDIMRNPAFFKEAVTVMDRLVRQMDYKGCRDLFGKVLGLYKTFSEGEDKVFVPAFKILKTKLETFRNSFKNVANMFSHRVIRQIVPIAGVGNYCMPPAILQHPQPSSVTNVPVNLLASTGALDLKGPLPYARCLQRPHTSLIRAVLTQQGSMDLLLSLLSLHTAPRASKISRCLFLERCLIDTILWTADETEACESDSEMAWADMMWRHLGLYSIHLCRLHLVRFPEMCLGVLEGLQDRRDSLSRSAPHIAWMLFNFLGAQNKNPLVDFAPILRILDALFPGGAPAFDTTLLVWFSLTQKSSAPNERLPRALPPPMQPMMSELMEKFQQMSQSPSYQVPLDPEEFRWFAYVYNAYAPLGQPQVVSPLNSKLVEALKQSDAIAPSYSSLRQLATMSLLAINSLLYNLLSTHADSPVVLDTYARITVLMHHDLNLQPKSVLTEAFTKAGNTGGSRVLAFVFELATYHLNSVEPMQRHLLLQNLVTLAKANRLGLDTELCLYRQAQALLTPALQVTNNHVKKLYVAWICGSDQEELNKYLLLQINHQLIHQQADPDGLLLSDFVQPLFQKCSAACLVPISMQPRLLASPDRISVPSAERQSHQLTGSAELATRLSQRILQEGQCDEAQLSDPSAGCLYWVALSCLRERGGDLPAAQLFARVQESLGPKGALPHLRIFCDLLTREVASAADNAEVSALHHVTSLVYTHRLFPLHRLLLVLLMRPFAERRLELAAFRVLRHLLSADTPNSPMAGLVPVLNSFPPSGGANGSLSALVSQLRQVYDDTPGGSSSSASLYSHAAIRVALLMDTALARLVQLQPPDSCALLSATLAPFLRHMPAPGTCLISLLSVYDPPAPLRLYLAAALLAPRMEAAADGAYLPSDCLPFFKSLLASPSLPAPAAQASSSDWLSCIGPPEAALNRLSLALSSHGRRGFPQLDWFGHEWPSSCSHAVNCCALQLLLCPVDLPAPVMPPRTAGLSSGFILSSKSKPHSNRQSDGGAAAKKARLEAEQDAFLDADDGGDGEEDDEGGGEESEDADEDEVDKLDWQSAGLLLAQMPARFTTRLVQQPLLALYDQLSGAAPHKALGHELASRPEVCLWFAYLSHAGPGRVAQLPNELVAELYHCLAEVDAACSGRLEHQDALADYFYHIKYMFVGDGVRRVASSVIERLSPSMQSRLRSIAPGHQPDGPADAPNFPAQSEN
Length1230
PositionTail
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.07
Grand average of hydropathy-0.024
Instability index54.78
Isoelectric point6.05
Molecular weight135181.93
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10715
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.43|      15|      17|     837|     851|       1
---------------------------------------------------------------------------
  837-  851 (26.29/14.01)	TALARLVQLQPPDSC
  857-  871 (29.14/16.42)	TLAPFLRHMPAPGTC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     128.28|      28|      73|     924|     951|       2
---------------------------------------------------------------------------
  316-  341 (37.76/17.58)	..AP.....AFDTTLLVWFSLTQKSSAPNERLP
  924-  951 (51.47/26.60)	LPAP.....AAQASSSDWLSCIGPPEAALNRLS
  994- 1024 (39.05/18.43)	LPAPvmpprTAGLSSGFILSSKSKPHS..NRQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.57|      34|     652|     111|     150|       3
---------------------------------------------------------------------------
  111-  150 (51.10/43.92)	RVIRQIV.......PIAGvgnycMPPAILQHPqPSSVTNVPVNLLAS
  764-  804 (53.47/29.20)	RVLRHLLsadtpnsPMAG.....LVPVLNSFP.PSGGANGSLSALVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.50|      21|      73|    1082|    1102|       4
---------------------------------------------------------------------------
 1082- 1102 (37.38/24.19)	LAQMPARFTTRLVQQPLLALY
 1154- 1174 (37.12/23.96)	LAEVDAACSGRLEHQDALADY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.34|      30|      73|     422|     451|       5
---------------------------------------------------------------------------
  422-  451 (46.43/25.70)	QLATMSL.LAINSL.....L...YNLLSTHADSPVVLDT
  457-  487 (26.14/11.39)	VLMHHDLnLQPKSV.....LteaFTKAGNTGGSRVL...
  492-  526 (39.77/21.00)	ELATYHL.NSVEPMqrhllL...QNLVTLAKANRLGLDT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.89|      24|      47|     345|     368|       6
---------------------------------------------------------------------------
  345-  368 (48.07/27.03)	PPPMQPMMSELMEKFQQMSQ.SPSY
  393-  417 (36.83/19.10)	PQVVSPLNSKLVEALKQSDAiAPSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.24|      13|      17|     674|     687|       7
---------------------------------------------------------------------------
  674-  687 (18.77/14.15)	LRERGGdLPAAQLF
  694-  706 (24.47/13.52)	LGPKGA.LPHLRIF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.75|      24|      53|     185|     212|      11
---------------------------------------------------------------------------
  185-  212 (36.05/26.58)	DLL...LSLLSLHTapraSKISRCLFLERCL
  236-  262 (41.69/21.47)	DMMwrhLGLYSIHL....CRLHLVRFPEMCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.39|      15|     745|     374|     389|      13
---------------------------------------------------------------------------
  374-  389 (27.68/19.87)	PEEFRWFAYVYNAyAP
 1122- 1136 (32.71/18.36)	PEVCLWFAYLSHA.GP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.93|      18|     177|     628|     645|      15
---------------------------------------------------------------------------
  611-  628 (29.04/15.75)	QPRLLASPDRISVPSAER
  629-  646 (27.88/14.82)	QSHQLTGSAELATRLSQR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10715 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LEAEQDAFLDADDGGDGEEDDEGGGEESEDADEDEV
1035
1070










Molecular Recognition Features






MoRF SequenceStartStop




NANANA