<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10704

Description Uncharacterized protein
SequenceMTAPNTASSKISTFDPARPERWTVYEERLEQYFIAKSITKEEIKRAELITVIGHVEKACRTKQKQFSGNQPPHSKKKFEPKQSYKGRKIKHLSANGSPGSSEESYDFSDVKNVAVNSNYEAKRMSAQKARFKPFTETLQVNGSPIKFRTTVRYSDPAIREPLKAFGKYAGECLPKYIQSADVTIFDELEILIHPEGVLPVLSFLKDHHAGSSDICCVDVPSRQFRFEVVYNLLSLRYNCRARVKTYTDELTPLESCCSVFQAANWYEREVWDMFGVYFTNHPDLRRILTDYGFQGHPFRKDFPLVGYNEYRYDDEQKRVVIEPVELAQDFRKFEYSTPWEVFPNYRDADKNMRKEGAGDENRRLAAMKFEEIECIHLAMMVSEKLTFIDDFLTISMVFLFGSLVFLVLFSTASTFQQQRVPNTEVYLQGSVLKPFTEFLLTRLRGICDSPGTSSGTRSPGTRLRLRWSLLHPHLPAYLRYLGIPESADHRVMSRAAYEVPVFPLDAARQLVEAMGFQHEFDFIAEGTVFRRGLLKVTVYRVYRPGHAREQLQCMLEDLQSSYDSATRQVNQCVAQTVAREASVDFASSSRLTLEDLYDSVTSDSSVDNGTDE
Length612
PositionHead
OrganismMacrostomum lignano
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Rhabditophora> Macrostomorpha> Macrostomida> Macrostomidae> Macrostomum.
Aromaticity0.11
Grand average of hydropathy-0.444
Instability index47.63
Isoelectric point6.73
Molecular weight70259.80
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
NADH dehydrogenase (ubiquinone) activity	GO:0008137	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10704
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.12|      34|      39|     414|     449|       1
---------------------------------------------------------------------------
  414-  449 (57.36/46.35)	TFQQQRVPNTEVYLQGSVLKP.FTEFLltRLRGICDS
  452-  486 (58.76/40.89)	TSSGTRSPGTRLRLRWSLLHPhLPAYL..RYLGIPES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.75|      21|      39|     501|     521|       2
---------------------------------------------------------------------------
  501-  521 (37.17/29.63)	VFPLDAARQLVEAM..GFQHEFD
  541-  563 (34.58/26.98)	VYRPGHAREQLQCMleDLQSSYD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.49|      21|      32|     298|     318|       3
---------------------------------------------------------------------------
  298-  318 (40.32/24.50)	FRK.DF..PLVGYNEYRYDDEQKR
  330-  353 (33.17/18.94)	FRKfEYstPWEVFPNYRDADKNMR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.45|      43|      44|      66|     109|       4
---------------------------------------------------------------------------
   66-  109 (72.05/48.76)	FSGNQPPHSKKKFEPKQSYKGRkIKHLSANGSPGSSEESYDFSD
  113-  155 (72.40/44.74)	VAVNSNYEAKRMSAQKARFKPF.TETLQVNGSPIKFRTTVRYSD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10704 with Med18 domain of Kingdom Metazoa
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