<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10682

Description Uncharacterized protein
SequenceMSSKSFTTTHWHQHTADKKPLKKSHKSNFPDVYPQELRQEEDTLTADRISRGYITRHTPHEHDSFIFNTKTKMDGGRLEETLLKCGSFCQAVIVKKNEDNAKMSKKVIKEQTLSNYTTLLTNKKFGSTASYANWFEDLSKNRSSNSLVKKWPVFQDKDECFEYLYMFKMSPMKAIWYLKVASIFDVFAFKNSFPPKKSTFDNLALDYTHNRIVKYMRYTFLEMSRLEEVEGSPVYKKWPYFAMLFKHAFEDGIVDRYEFLLEICDLLGELIEFPLHKPTVFKILLLYGASFGPFIFQNTVICRRIAFVICQRIKRYHQDFNDKMKRTMEGARVFTVQESLSELMACKDNGEVLEVMFAFLAGIIIDCPLAVIRNANKIECHIPLTRNGYRVENFKESKKIFVHLSESPFCELPCEIDKLICYDLFKSPFIQEKLCEGLANINERSKGIETRWKSSFDFGTEQQEISNAITEMIELLDNIFIINDHKMKESTNKLFNPTTKPKFENEKAIKMRFLLKWATTAQRNSIHRGMVAAKFMKVILENVQDTNEVVMNTFIDFLDTEGPKVGDINYDVEFGNVVYLFMELQNIGLLNFHAYMWSLIKNGKYDMDTAVIDKYEFAKATNLPSKIAWNNTTKVTTHNNFQLRSEISEAREALNMPELSTFDRILYQLPIPQGKGQKSANLLHYHLIYGHAINKMEAIKHASNTANSILAIWKQQMWFIFDVTKLRFTLHNQKLLATNNKNILHQFKSSSYRDQVIIAHEVSADLLEEVYNFKTKNADKFPTSEAFDIVIKMFEISKDLNGFIVWADNILKYLIEADQLITFFNYNVRTGAIVHPCVYSIVGALSEHFQYFLMHPKAPDICGHVYNFIQKEVNIEKYGMNGSTPPIVMFLHACKVYLSTYGIYKQNGAPPLDQHLARAYPPIYSPNLHEKIEPTQISHNETFLMRDIRESSRAQRSNSFRIQIKQLTVPRDNNRYSFMLNCYQAAICCGKDTERLINLTNYVAAVSHNANFHEEWLEFFLDICCGGILKPPAANYMETILAIEAKDRFAISTFIALLVGKYVVSPKNFIQKLMESTFLNCYKKDEHAISSAKMSICIAIETVAKIFTADLEPIRVDKFEHKKPKHLPTLSLGIGKHRSREVISEVKVEPAKTSLVSSTKKPSYVRVGEMKSLAILHLRELDTVLINLLKLLNVIYEKLQKAFKVPAIEFLAEYLKTAVYAICEKTWVVEKVYLMLNLIPVTDFNRVVLGKKSYVMEQTNFFRLTLRRKIERQLKVDLTTAFTSASHKKYVDLSLANLTIWNLRATSYDLQGMLDNMLSDSKTSETSVKMQNSEQLKSIIGRSVHDMFLVKENRFCVIPPFETGDHFRIVNLTNKWLVSRLLALIEATKPADKNGSTINSKFLAEVQKIFDATVETNRDRFVMATWLLSQYSFHNLVTNCLVRETNAEHGIVEKLFKYFLDLINKSKTRSISRLKDDVEREGLILRISLVGGMFDKICNVKCIEKWCVTLYQLLFFEIVSPERDPKLFEITFDILYSVLHNTLISGVNNIEDEPIDTKRMTDLMANNNYYKKRFHNYFVTVKKIRKEAQDKYISSSARILLQLLPLNKKIYEYMMTEPYGGKQLPPIPVNRRNGNRTNAHARDAANSRLYLRGGYKVCDKLKLTSFDIIHAAHFELSLKKNMNFNCFQVFSFDKKPEPIQRSIVRLLYHKHYLEFPRMSIVGIERDPKEDILLCQPQIELIDVPEEDIINDVQSIPIKPPPRVPNVPTTIPDPMARIENGPASVKDDESVLSTLLLSVESKSSPIAPISAPMSIPKILSIEDISGSVPPVLANQTIPNSLKRPFPPALSTSQPPNIPPLISSIENKMDPYSASNPMVKPTLVPEVPNIPANSAQQPISTSSTAITSQQKPIFNQPPRPDIEMMPVQPILPIPPTQGLHRPHHLPPITMPNQITSGTNPLAPKPLPNINQPPHYNQSQSQTNLQSMLNNPQTSGQKLSQMNGPYLNQQPSAKSNSTTSNQGSQNMPNIVTQNNISQVNQSPMVSQPPPITIPTPTKQNRKRAQNPNGPPQPKPPKKKKEPKGSANNDITIIEQNNGIPNGMSSQVGNPSGMRQSDISANPNNSSINSQPMNSQPPMMNSGPPQNIHNQPLNSNVNRPSNNLAMPNQNANIGPGNMSHSMSQPSIANQQGIPNIRNPHMNGPGMQNSNQQPNIHGQNINNTQGHMLNHPHNAQQMDMMQINRPSLGINSHDNQSMGHSGINAPNNQPPLLSHHNPANQPKPPIPQNPPNLLNHPNSNQSAQQHITNPGMNQNSQLSNNPPTLSIQHPNPNMSNQQSHSHQHLNSQPNLHSGQMHHKQPPNSMHESANQLHGSNGQVLQSNLSSIHPPNQSQGNMIGSQSSMQGGQPPTHPNPIHPNNPSQSNQGSSQGNHNPAQPNQNSSQANQNPMQGNQGGPMQNAMVNMGNQNVGVAGPMANPQNQGQMGGNQNVSNQGSIQGMGNQQGCMQNFGTSIGSINNQPPMQNANNQPMQNVNNQGSMQNVNNQVPMQNSSNQGSMHNAGQGMGPLIHPSLNQQSMHPNLGQQAQMNNPNINSSQAMHGSGAQMSGHQMHAIQGPGGMNQGIMNNPGQPPNQPSHLNPHQMNGGQQMNPGHGMNAGSMSQNMNSGLNQNMNLGINHNSLNAPINQQSHLTPNPNLNQQMPSMNSGMNPQQSHVPLNSSMNAQLSSQHNLNSGMNQSGHPGMTQHPSQNNLSSAGMNAGLGQGSNQSMNSGMSQGMSNVMNQGIHPGMTQQLPPHQNINSGMNQPPPHPNLSGAINQSSHQSLTPAMNSNMSQPGSQPIHQPNSQTMHQPNSQSIHQSNTQTMHQPGSQPNAPQMHPSQSMQQPNHSMNSQNNILSRHIPPNNGNAMNIGMNNPNSMGNPNAINNNQMNNNLMNNSSMNGNPMNIPPMNNAMNNGPMNAMHSSSMNQGPMNGGASSGMNAGPNNPMNSMGGNVGMNINPLHSNNQLPQQQQHHLPNQQGQGAPPMSHQQIKSMQQHQLGNQHGQQGGMSGGYSQQQPNSLMNPGQGGGNNMMNQGPGMVGNMQQNANAPYYGQNQSSQQMPPNIPPQNMPHQMGQQGGQIPPPHLQHQMPPHQNVGANQMGQPNANMIRQQQMHQQQQMTHQSQGNQMGQQQLHNQQQIGPQHNVHQQQIAPQHPNAQNNWSSNVHGQQMNSMPNGQQLQQQRNNVGISTKDKLNSIIKNKQHANINNQQINPMAGQPQNGYDMHGPPKHNHMANPYEGNVQQNQHQQRTDMMMNSQQQQQSSHSQMQHQQQLQMAQQLPNTQQQHNPTQQGMGMQGQGMQHPHNQQQHPQYNQHNYQSKPF
Length3358
PositionKinase
OrganismRhabditophanes sp. KR3021
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Alloionematidae> Rhabditophanes> unclassified Rhabditophanes.
Aromaticity0.06
Grand average of hydropathy-0.674
Instability index49.62
Isoelectric point9.12
Molecular weight376687.82
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10682
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            20|    1197.33|      64|      64|    2549|    2612|       1
---------------------------------------------------------------------------
 1964- 2023 (58.14/ 9.82)	LP.N.......I....NQ..PPH.YNQ..S...QSQTN.LQSM..........................lN....N.P.QT.S..G..QK.LSQ........M....NG....P...YL...N...QQpsaksnS.T.T...S.NQG.SQ.......N
 2024- 2084 (52.10/ 8.02)	MP.N.......IvtqnNI..SQV...N..Q...SPMVS.QPPP....I...T.IP....TP......tkqNR..KR.A.QN.P..N......GP.............PQ....P...KP...P...KK......K.K.E...P......K.GS..A.N
 2130- 2198 (58.39/ 9.89)	................NS..QPP.MMN..S...GPPQN.IH.............N....QPlnsnvnrpsNN..LA.M.PN.Q..N..AN.IGP......gnM....SHsmsqP...SI..aN...QQ......G.I.....P.NI..RN.PH..M.N
 2240- 2315 (50.53/ 7.55)	RP.S.....lgI....NShdNQS.MGH..S...GINAP.NNQP....P...L.LS....HH.........NP..........A..N..QP.KPPipqnppnlL....NH....P...NS...N...QS......AqQ.HitnP.GMN.QN.SQ..LsN
 2316- 2378 (70.30/13.44)	NP.P.......T....LS..IQ...H...P...NPNMS.NQQS....H...S.HQhlnsQP.......nlHS..GQ.M.HH.K.....QP.PNS........M.....H....E...SA...N...Q.........L.H...G.SNG.QV.LQ..S.N
 2379- 2429 (51.72/ 7.91)	LS.S.......I.hppNQ..SQGnMIG..S...QSSMQ.GGQP....P...T.HP....NP.........I.....................................H....P...NN...P...SQ......S.........NQGsSQ.GN..H.N
 2432- 2472 (47.46/ 6.64)	QP.N.......Q....NS..SQA.N.............................Q....NP......mqgNQ..GGpM.QN.A..M..VN.MG.........................................N.......Q.NVG.VA.GP..M.A
 2473- 2536 (60.11/10.40)	NP.Q................NQ............GQMG.GNQNvsnqG...S.IQ....GM.......gnQQ..GC.M.QN.F..G..TS.IGS........I...nNQ....P...PMqnaN...NQ......P.M.Q.....NVN.NQ.GS..M.Q
 2537- 2584 (78.27/15.81)	...N.......V....NN..QVP.M.............................Q....NS........sNQ..GS.M.HN.A..G..QG.MGP........L....IH....P...SL...N...QQ......S.M.H...P.NLG.QQ.AQ..M.N
 2585- 2629 (76.31/15.22)	NP.N.......I....NS..SQA.MHG..S...GAQMS.GHQM....H...A.IQ....GP......ggmNQ..GI.M.NN.P..G..Q....P................................................P.N...Q.........
 2630- 2687 (59.34/10.18)	.PsH.......L....NP..HQ..MNG......GQQMNpGHGM....N...A......................GS.MsQN.M..N..SG.LNQ........N....MN....L...GI...N...HN......S.L.N...A.PIN.QQ.SH..L.T
 2689- 2745 (64.16/11.61)	NP.N.......L....N....QQ.MPSmnS...G..MN.PQQS....H.....V......P....lnssmNAqlSS.Q.HN.L..N..SG.M..............................N....Q......S.G.H...P.GMT.QH.PS..Q.N
 2746- 2799 (53.37/ 8.40)	N...............LS..S........A...G........M....N...A.GL....GQ.......gsNQ...S.M..N.S..GmsQG.MSN........VmnqgIH....P...GM...T...QQ........L.P...P.HQN.IN.SG..M.N
 2845- 2908 (64.99/11.86)	QP.N................SQS.IHQ..S...NTQ.T.MHQ..................P.....gsqpNA..PQ.M.H..P..S..QS.MQQ........P....NH........SM...N...SQ..nnilS.R.H.ipP.NNG.NA.MNigM.N
 2909- 2975 (63.43/11.39)	NP.NsmgnpnaI....NN..NQ..MNN..NlmnNSSMN.GNPM....N.........................iPP.M.NN.A.....MN.NGP........M..naMH...sS...SM...N...QG......P.M.......NGG.AS.SG..M.N
 2977- 3045 (71.98/13.94)	GP.N............NP..MNS.M.G..G...NVGMN.INPL....H...SnNQ....LP.......qqQQ..HH.L.PNqQ..G..QG.APP........M....SH....QqikSM...Q...QH......Q.L.G...N.QHG.QQ.GG..M.S
 3058- 3117 (67.61/12.64)	NP.G.......Q....GG..GNN.MMN..Q...GPGMV.GNMQ....Q...N.AN....AP.....yygqNQ..SS............QQ.MPP........N....IP....P.............Q......N.M.P...H.QMG.QQgGQ..I.P
 3118- 3156 (45.69/ 6.12)	PP.H.......L....Q........H.........QMP.PHQ.........................................nvG..ANqMG...............Q....P...NA...NmirQQ......Q.M.H.........QQ.QQ..M.T
 3239- 3297 (57.62/ 9.66)	HA.N.......I....NN..QQI.NPM..A...GQPQN.GYDM....H...........GP........pKH..NH.M.AN.P..Y..EG.N...............VQ....Q...NQ...H...QQ....rtD.M.M...M.NSQ.QQ.QQ.....
 3298- 3349 (45.81/ 6.15)	..........................S..S...HSQMQ..HQQ....QlqmA.QQ....LP.........NT..QQ.Q.HNpT..Q..QG.MG.........................M...Q...GQ......G.MqH...PhNQQ.QH.PQ..Y.N
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.86|      29|      31|    1827|    1857|       2
---------------------------------------------------------------------------
 1827- 1857 (50.04/26.00)	VPPVLANqtIP.NSLKRPF...PPALSTSQPP..NIP
 1881- 1915 (30.82/ 9.57)	LVPEVPN..IPaNSAQQPIstsSTAITSQQKPifNQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.24|      21|      31|     746|     766|       3
---------------------------------------------------------------------------
  746-  766 (36.30/28.56)	QFKSSSYRDQVIIAHEVSADL
  780-  800 (36.94/29.23)	KFPTSEAFDIVIKMFEISKDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.35|      33|      35|    1020|    1052|       4
---------------------------------------------------------------------------
  987- 1018 (35.53/25.54)	...ICCGKDTE.RLINL....TN.YVAAVSHNANFHeewLE
 1020- 1052 (58.21/48.35)	FLDICCGGILKPPAANY....ME.TILAIEAKDRFA...IS
 1054- 1090 (43.61/33.66)	FIALLVGKYVVSP.KNFiqklMEsTFLNCYKKDEHA...IS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.01|      31|     532|     174|     211|       5
---------------------------------------------------------------------------
  174-  211 (46.55/44.80)	AIWYLKVASIFDVFAFKnsFppkksTFDNLALDYTHNR
  711-  741 (58.46/35.46)	AIWKQQMWFIFDVTKLR..F.....TLHNQKLLATNNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.62|      20|      34|    3160|    3185|       6
---------------------------------------------------------------------------
 3163- 3184 (35.74/23.36)	QMGQQqlHNQQQIGPQHNVHQQ
 3185- 3204 (38.88/14.50)	QIAPQ..HPNAQNNWSSNVHGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.89|      17|      34|    1539|    1556|      12
---------------------------------------------------------------------------
 1539- 1556 (24.94/17.22)	LHNTLISgVNNIEDEPID
 1574- 1590 (29.95/15.99)	FHNYFVT.VKKIRKEAQD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.53|      13|      35|    1122|    1139|      13
---------------------------------------------------------------------------
 1122- 1139 (18.17/22.75)	KKPKHlptlsLGIGKHRS
 1160- 1172 (23.36/13.34)	KKPSY.....VRVGEMKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.16|      18|      26|     878|     901|      14
---------------------------------------------------------------------------
  881-  901 (26.36/24.37)	NGStPPIVMflHACKVYLSTY
  907-  924 (35.80/12.86)	NGA.PPLDQ..HLARAYPPIY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.31|      20|      26|    1415|    1437|      15
---------------------------------------------------------------------------
 1415- 1437 (26.74/33.44)	ETNRDRFVMATwlLSQYsFHNLV
 1444- 1463 (34.57/25.27)	ETNAEHGIVEK..LFKY.FLDLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.80|      23|      24|     820|     842|      17
---------------------------------------------------------------------------
  820-  842 (41.39/25.77)	LITFFNYNVRTGAIVHPC..VYSIV
  845-  869 (39.41/24.13)	LSEHFQYFLMHPKAPDICghVYNFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.81|      11|      32|    1773|    1784|      18
---------------------------------------------------------------------------
 1773- 1784 (16.73/12.96)	PMARIeNGPASV
 1804- 1814 (21.08/11.32)	PIAPI.SAPMSI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.21|      14|      24|    1736|    1751|      25
---------------------------------------------------------------------------
 1736- 1751 (20.16/16.30)	PQIELIDVPeeDIIND
 1759- 1772 (28.04/16.16)	PPPRVPNVP..TTIPD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10682 with Med12 domain of Kingdom Metazoa
Unable to open file!