<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10676

Description Uncharacterized protein
SequenceMSMIDARFREQLAHRRERVEDIYHFQNQKIGRGTYGHVYKAVPRVPSTQVYALKLIEGTGLSMSACREISLLRELRHINLIKLNRVFLTAERKVWLLFDYAEHDLWHIIKYNRSMKSKKQRVDVSATMVKSLLHQILDGMHYLHSNWILHRDLKPANILVMGEGISRERGRVKIADMGFARIFNNPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDLWAIGCIFSELLTSEPIFFCGEEDIKASSPYHKGQIQRIFQIMGYPAEADWTDIREKFAHFALSKYMDKHRLKTDTKQFALLQKLLTMDPMKRISAQTAMEDEYFKESPPTTQDVFNGLPIPYPKREFLNDEEGKDPLANMNLQPHHAQPPPNKRVKMDADVNQFNKPINNPHDINHQGNDGMNNIQDQKPQMAMYLDNNMINRQHQQPAQFNQMYQHDLARRQQEQLRDQKMKEEIQHQQRNMIMHQGGSNPNQGRDIQMGMMNFEQQQVHPNRPANLIMPDNNRDPNTGQFQNVQQQRMIQQQQQQQQQQIHGIPGPTNPNYGWQGGNARYNPQ
Length555
PositionKinase
OrganismRhabditophanes sp. KR3021
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Alloionematidae> Rhabditophanes> unclassified Rhabditophanes.
Aromaticity0.08
Grand average of hydropathy-0.791
Instability index48.49
Isoelectric point9.22
Molecular weight64937.37
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10676
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      94.09|      16|      16|     408|     423|       1
---------------------------------------------------------------------------
  411-  428 (23.58/ 8.98)	QMAMY.LDNNMINRqhQQP
  430-  445 (24.64/ 9.69)	QFNQM.YQHDLARR..QQE
  479-  495 (21.29/ 7.44)	QMGMMnFEQQQVHP..NRP
  511-  526 (24.58/ 9.66)	QFQNV.QQQRMIQQ..QQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.64|      21|      27|      63|      85|       2
---------------------------------------------------------------------------
   63-   85 (33.29/26.26)	MSACREISLL.....RELRHInlIKLNR
   88-  113 (35.35/21.44)	LTAERKVWLLfdyaeHDLWHI..IKYNR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.92|      25|      27|     341|     365|       3
---------------------------------------------------------------------------
  341-  363 (36.06/15.10)	.....PYPKREFLND...EEGKDPLANMNLQ
  364-  390 (26.00/ 9.20)	PHhaqPPPNKRVKMDadvNQFNKPINN....
  391-  408 (27.86/10.29)	PH.diNH............QGNDGMNNIQDQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.30|      14|      32|     462|     475|       4
---------------------------------------------------------------------------
  462-  475 (29.39/14.81)	NMIMH..QGGSNPNQG
  497-  510 (26.42/12.64)	NLIMP..DNNRDPNTG
  530-  544 (22.49/ 9.76)	QQI.HgiPGPTNPNYG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     225.21|      67|     120|     125|     195|       5
---------------------------------------------------------------------------
  125-  195 (103.70/78.71)	SATMVKSLLHQILDGMHY.LHSNWILHRDlKPANiLVMGEGIsrERGRVKIADM.GFARIFNNPL..KPL...ADLDP
  207-  244 (19.53/ 6.14)	...................................LLLG.....ARHYTKAIDLwAIGCIFSELLtsEPIffcGEEDI
  247-  309 (101.98/63.55)	SSPYHKGQIQRIFQIMGYpAEADWTDIRE.KFAH.FALSKYM..DKHRLKTDTK.QFAL.....L..QKL...LTMDP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10676 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) VFNGLPIPYPKREFLNDEEGKDPLANMNLQPHHAQPPPNKRVKMDADVNQFNKPINNPHDINHQGNDGMNNIQDQKPQMAMYLDNNMINRQHQQPAQFNQMYQHDLARRQQEQLRDQKMKEEIQHQQRNMIMHQGGSNPNQGRDIQMGMMNFEQQQVHPNRPANLIMPDNNRDPNTGQFQNVQQQRMIQQQQQQQQQQIHGIPGPTNPNYGWQGGNARYNPQ
334
555










Molecular Recognition Features






MoRF SequenceStartStop




1) NYGWQGGN
542
549