<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10662

Description Uncharacterized protein
SequenceMESLIPVISKLQDVFATIGCRGADVELPQIVVIGSQSSGKSSAIEGIVGRDFLPRGTGIVTRRPLILHLSHSPLKSALREQKKAPALDEWAEFGHAPGVIYTNFDEVRQEIERETERVTGSNKGISSVAITLTIYSHNVVNLSLVDLPGITKVPVGDQPADIELQIRKMLFGYISNPNSIILSVMPANQDFATSESLKIAREVDKEGNRTLVLLTKLDLMDQGTDAMDVLTGRLVPVKLGIIGIVNRSQADIIANKSIKDCLKDESKFLQTKYPTLASQNGVPYLTKTLNRLLMVIFIYPFALKLIYFQHHIRECLPQLKLRINTLMVHCQTILRSFGEAVIDKNRTLLHIITHFATAYNSTIDGTARNIETTELCGGARICYIFHETFTRALECFDPLENLNKLDVLTAIRNATGLRPSLFIPEVSFELLVKKQIERLEEPAITCVDLVYEEMLRIVQHCGIEVQQEMQRFPHLYERIHEVINHVLSDRLPPTKEFVSNLVSIQLAYINTKHPEFASDASLINSLQGASSDESMAMITEKVPASEAADGKTTTASLPNLENGTNGPTNVFGESAFYADIQNKVNLKKLHPTYWFNRNANKVEDDSDLGMDNGDGSAGVLTRTDKTVRRPLSVREKRDIAVIERLIKGYFIIVRKSIQDLVPKAIMNFLVNNVKENLQSELVRRLYNADDLNTLLAESDAITQKRAESAEMLTEMIFEQAGAVAPPYTSKHFRVDCIWYRPQQHIATLISGFYVIHHSNFPDSAFIINANKPDSQPASESGSAERPTATRSSAAPRATADKGFELQLDKFQSAGLTVEPTKFEVVGNEYHLKDFRLRVGTVTLGSSVKGTIVEIEYAASNIVMQCHELLQEIIDIFFPDYALKTPEIIRKQHSQPDNYTAIDTAQQYLDIFSVMRKRS
Length918
PositionHead
OrganismMeloidogyne hapla (Root-knot nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Tylenchomorpha> Tylenchoidea> Meloidogynidae> Meloidogyninae> Meloidogyne.
Aromaticity0.07
Grand average of hydropathy-0.156
Instability index42.06
Isoelectric point6.08
Molecular weight102581.31
Publications









Function






Annotated function


GO - Cellular Component
clathrin-coated pit	GO:0005905	IEA:UniProtKB-KW
cytosol	GO:0005829	IEA:UniProtKB-SubCell
Golgi apparatus	GO:0005794	IEA:UniProtKB-SubCell
mediator complex	GO:0016592	IEA:InterPro
mitochondrial outer membrane	GO:0005741	IEA:UniProtKB-SubCell
peroxisome	GO:0005777	IEA:UniProtKB-SubCell
synaptic vesicle membrane	GO:0030672	IEA:UniProtKB-SubCell

GO - Biological Function
GTP binding	GO:0005525	IEA:UniProtKB-KW
GTPase activity	GO:0003924	IEA:InterPro
lipid binding	GO:0008289	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
mitochondrial fission	GO:0000266	IEA:InterPro
peroxisome fission	GO:0016559	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
rhythmic process	GO:0048511	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10662
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     616.10|     203|     237|     337|     555|       1
---------------------------------------------------------------------------
  337-  555 (313.96/261.14)	FGEA.....VIDK.NRTLLHIITHFATAYNSTIDGTARNIETTElcGGARICYIFHETFTRalecfdPLENLNKLDVLTAIRNATG....LRPSL..FIPEVSFELLVKKQIERLEEPAITCVdLVYEEMLRIVQHCGIEVQQEMQRFPHLYERIHEVINHVlsdrLPP..TKEF............VSNLVSiqlAYINTKHPEFASDASLINSLQGASSDESMAMITEKVPASEAADGKTTTA
  571-  799 (302.13/210.98)	FGESafyadIQNKvNLKKLHPTYWFNRNANKVEDDSDLGMDNGD..GSAGVLTRTDKTVRR......PLSVREKRDIAVIERLIKGyfiiVRKSIqdLVPKAIMNFLVNNVKENLQSELVRRL.YNADDLNTLLAESDAITQKRAESAEMLTEMIFEQAGAV....APPytSKHFrvdciwyrpqqhIATLIS...GFYVIHHSNFPDSAFIINANKPDSQPASESGSAERPTATRSSAAPRATA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.32|      41|     136|       5|      52|       2
---------------------------------------------------------------------------
    5-   52 (56.14/62.37)	IPVISKLqdvfaTIGCRGADVELpQI..VVIGsQSSGKSSAIEGIV..GRDF
  147-  191 (65.18/46.30)	LPGITKV.....PVGDQPADIEL.QIrkMLFG.YISNPNSIILSVMpaNQDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.96|      35|     577|     272|     310|       4
---------------------------------------------------------------------------
  272-  310 (53.86/53.41)	KYptlASQNGVPYLTKTLNRLLMvIFIYPFALK...LIYFQH
  855-  892 (58.10/42.40)	EY...AASNIVMQCHELLQEIID.IFFPDYALKtpeIIRKQH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10662 with Med20 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SMAMITEKVPASEAADGKTTTASLPNLENGT
534
564










Molecular Recognition Features






MoRF SequenceStartStop




NANANA