<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10659

Description Uncharacterized protein
SequenceMVDANFRDELGRKREKVEELYTYEGNKVGRGTYGHVYKAMLKNAPVGVENKPFALKLIEGQGFSMSACREVSLLRELNHQNIIKLLRVFLTNEKRVWLLFDFAEHDLWHIIKYHRAAKQKNQRVMVPRGMVRSLLYQILEGINYLHDNWIMHRDLKPANILVMGEGTGNERGRVKIADMGFARIFHMPLKPLSELDPVVVTFWYRAPELLLCSKHYTKGIDIWAIGCIFAELLTSEPIFVCQEEDIKSQTPYHPAQLDKIFQVMGYPHIDEWPDIKKMPGYQKLNEDFDKPRREGKYKGASLKKYMEKYKQISGLPEPQTLEETFFLLDKMLTMDPQKRITAAEAKEHKYFKLDPTPTSDVFAGCKIPYPRREFLKDEPEDRNSGSKQQAPTLPVVAVPPTVPAHTHNPPTMEPPPGKKLRQQVVHTGGGGTQQQQQIQQQNQQAMMTGNGMVVVGGGAGGGVIPPPQQQQQMVIDQHQPHMNMTQGTLHGQTNMQIKSEFGQIKNEFAQIKSEFGTNMGIMDGSGGGNIQQMQQQNTGHFEVTGSHIMTGGPPQQGQQQQQMGGGGYPMQQQMFHSTGPQQSTQQQAHLSQQQQMQINNQMGGQNHGMIPQQQQMIHPNQQQQYIQQNMQQMTTNNQQPMMSSSQHQQQSSQQHLIQQQQQMNIQMQRQVAYSQQVQQQQQHIAQQQQMMQQQHMQQQMHIPPQQQMGVINPHQQQQFIMSQQQRMGHQQQQQPHNQHRPY
Length742
PositionKinase
OrganismMeloidogyne hapla (Root-knot nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Tylenchomorpha> Tylenchoidea> Meloidogynidae> Meloidogyninae> Meloidogyne.
Aromaticity0.07
Grand average of hydropathy-0.838
Instability index55.19
Isoelectric point8.99
Molecular weight85207.11
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10659
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     315.16|      36|      36|     653|     688|       1
---------------------------------------------------------------------------
  455-  490 (53.77/14.95)	VGGGAGGGVIPPPQQQQQMVIDQH....QPHMNMT.QG.TLH
  568-  599 (49.78/13.25)	YPMQQQMFHSTGPQQSTQ...QQA......HLSQQ.QQmQIN
  600-  634 (52.44/14.39)	NQMGGQ..NHGMIPQQQQMIHPNQ....QQQYIQQnMQ.QMT
  635-  664 (47.66/12.35)	TNNQQPMMSSS......QH..QQQ..ssQQHLIQQ.QQ.QMN
  665-  701 (58.90/17.14)	IQMQRQVAYSQQVQQQQQHIAQQQqmmqQQHM.Q...Q.QMH
  702-  737 (52.61/14.46)	IPPQQQMGVINPHQQQQFIMSQQQrmghQ....QQ.QQ.PHN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     207.86|      58|     136|     217|     287|       2
---------------------------------------------------------------------------
  217-  287 (93.08/74.29)	TKGIDIWAiGCIFA....ELLTSEPifvcqeEDIKS....QTPYHP..AQLDKIfqvmgyP.HIDEWPDIKKMPGYQKLNED
  297-  324 (29.01/ 8.46)	...........................................YKG..ASLKK.........YMEKYKQISGLPEPQTLEET
  356-  423 (85.77/43.91)	TPTSDVFA.GCKIPyprrEFLKDEP......EDRNSgskqQAPTLPvvAVPPTV......PaHTHNPPTMEPPPG.KKLRQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.47|      20|      94|     424|     449|       3
---------------------------------------------------------------------------
  505-  535 (26.31/ 7.17)	KNEFAqiksefgtnmgIMDGSGGGN.IQQMQQ
  536-  561 (26.17/17.98)	QNTGH......fevtgSHIMTGGPPqQGQQQQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10659 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IPYPRREFLKDEPEDRNSGSKQQAPTLPVVAVPPTVPAHTHNPPTMEPPPGKKLRQQVVHTGGGGTQQQQQIQQQNQQAMMTGNGMVVVGGGAGGGVIPPPQQQQQMVIDQHQPHMNMTQGTLHGQTNMQIKSEFGQIKNEFAQIKSEFGTNMGIMDGSGGGNIQQMQQQNTGHFEVTGSHIMTGGPPQQGQQQQQMGGGGYPMQQQMFHSTGPQQSTQQQAHLSQQQQMQINNQMGGQNHGMIPQQQQMIHPNQQQQYIQQNMQQMTTNNQQPMMSSSQHQQQSSQQHLIQQQQQMNI
2) QVQQQQQHIAQQQQMMQQQHMQQQMHIPPQQQMGVINPHQQQQFIMSQQQRMGHQQQQQPHNQHRPY
367
676
665
742










Molecular Recognition Features






MoRF SequenceStartStop




NANANA