<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10596
Description |
Mediator of RNA polymerase II transcription subunit 20 |
Sequence | MVGVAWVFEVPRLASAVDSALEQIGADKIGHYTVDCTPYNPSEGVQGSVQSCYLLHHSYCPESSFIQCGMVDSTKRTAATADRGFDLVLSKLSKGLTPDTPGKFEVTGNEYKIADFYIRVGAALMNSVSKGVIVEVEYAASALPSQCGGLLMEAVEQLFPELKREKPKIFSSHQEYIMCDTIEQYLKIFQDMRKKAT |
Length | 197 |
Position | Head |
Organism | Steinernema glaseri |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida>
Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Steinernematidae>
Steinernema.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.095 |
Instability index | 29.53 |
Isoelectric point | 5.40 |
Molecular weight | 21677.58 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP10596
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 71.05| 21| 24| 110| 130| 2
---------------------------------------------------------------------------
110- 130 (35.06/21.82) EYKIADFYIRVGAALMNSVSK
137- 157 (35.99/22.54) EYAASALPSQCGGLLMEAVEQ
---------------------------------------------------------------------------
|