<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10571

Description Uncharacterized protein
SequenceMFGTGQQAPSTAQPTGVNIAIEAGSEWGIQEIGFDGVEKYMRPLDYSDHVAKLARKVDWRKLIGAEATYDNPDALPRDDGEEVEEKEPEEVVIGMEDRKTPEAGPWHTVAKYLHEALQQVNVLVDTISVLKMPYLEALTVADAFEAQHNMQDVVQQSKQFQWVTRRKALGEAISVLEQAQKFRSKLLTETDPDKAMFFRELEKMRELWRVRKTGNVTYGDLGYKIFGSKYNPKELFDITRRAATSVSDGASLSTLSDSCLQVQVPCDLIRRSTIAVSIEIDNDDPKTLFATAENDLDYMKVDREQAMEVHWSKALQWAQESLLCRDIFKQLCKDAVILKDHITVIRDGVLIASLFDNILLRVELAFHPFKDGPLPTAGNDYLNRALRQLFLSDLCARNIRHQTFVAMPLSTLPNTLDLRGPYAMTDEEIESRLRQKRTLLERLLLLASHFVLTDRVTTSLKRYLLRVTDPQIMWKWLRATPVQSSIIVTASNRNYDYAGKTTFYIRIGAENFYVATKEGQNIECRRDDEMLVYTIDMLICNYMLNTVAMIASKLWQWQVLHANINATDDRAEPSPTVYMCNQSATRAIFMQFHLNEPPTIRIQKCLPSKPAAAEKPGEFLVLNYDRLVGSSLCRKIDNLCSMLRS
Length645
PositionHead
OrganismLoa loa (Eye worm) (Filaria loa)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Loa.
Aromaticity0.08
Grand average of hydropathy-0.298
Instability index48.12
Isoelectric point5.81
Molecular weight73539.45
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10571
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     247.54|      84|     275|     104|     197|       1
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  104-  197 (119.36/118.85)	GPWHTVAK.YLHEALQQV........NVLVDTIsvLKMPyLEALTVADAFEAQHNMQDVVQQSKqfqwVTRRKALGEAISVLeqAQKF..........RSKLLTETDPDkAMF
  372-  474 (128.18/91.26)	GPLPTAGNdYLNRALRQLflsdlcarNIRHQTF..VAMP.LSTLPNTLDLRGPYAMTDEEIESR....LRQKRTLLERLLLL..ASHFvltdrvttslKRYLLRVTDPQ.IMW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.29|      11|      28|     237|     247|       4
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  237-  247 (18.21/14.66)	DITRRAATSVS
  267-  277 (18.08/14.50)	DLIRRSTIAVS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10571 with Med17 domain of Kingdom Metazoa
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