<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10566

Description Uncharacterized protein
SequenceMNYVDQQQFIMQQGQRMQNPRMISVPTTVTPQHLHRQQRYGMTMMQPGQQPVQIASGQYVQNPQMQPRLLTMSDALSRLPPEVQQMAQQQINAETNAEKKRQVALGFIQGRVRLTQQYPGQGTMNAGGMMISVGLNQQVGNTQMVRMGTMQGGPVPYPAQSVSLQTGMGQMGPTQVSVQRMPNHYMASGMSGPQSMQYQSQDPGNVQNYNSQQQITLTQPSSVGPTVQQTSSLHHKGPNSVPSAIYTQHHPESAAPAHSTTGNKNDKSSDEPLYSQKLELLKPYHEHIKRLLERNRLDGQAPKSKFERLLEIMENRRKVELKLLEKLVVSVRNLIERDSLCFPLIDALRLESSEATKTPLPDPWGDFHQYAIKIPEKVMSLVKDEKTKSRESNDVTPVKRIKKEEGSDERIAVICQDGSRLELSQEASDQLRPYNYRFDPEFIPISDECTEIQVFIENDVLLVPPLRLVVPLNYPESRASIWRDRWSYGGVSLIDINTQFDKRLNMAVNCRSITEIVNAWKLASLHVLKIGSSSAST
Length537
PositionTail
OrganismLoa loa (Eye worm) (Filaria loa)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Loa.
Aromaticity0.05
Grand average of hydropathy-0.623
Instability index48.62
Isoelectric point8.92
Molecular weight60585.30
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats
>MDP10566
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.46|      27|      30|     219|     248|       1
---------------------------------------------------------------------------
  219-  248 (43.32/29.74)	QPSSVGPTVQQTSslhHKGPNSVPSAIYTQ
  250-  276 (48.14/25.74)	HPESAAPAHSTTG...NKNDKSSDEPLYSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     169.09|      31|      31|     138|     168|       2
---------------------------------------------------------------------------
   38-   58 (23.98/ 7.72)	...........QR.Y..GMTMMQPGQ..QPVQIASGQ...
   60-   84 (21.85/ 6.44)	.VQ......NPQMqP..RLLTMSDALSRLPPE...VQ...
   90-  118 (24.69/ 8.15)	QINaetnaeKKRQ.V..ALGFIQG........RVRLTQQY
  138-  168 (60.19/29.60)	QVG......NTQM.V..RMGTMQGGPVPYPAQSVSLQTGM
  170-  196 (38.38/16.42)	QMG......PTQV.SvqRM......PNHYMASGMSGPQSM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.24|      21|      41|     277|     297|       4
---------------------------------------------------------------------------
  277-  297 (35.50/27.93)	KLELLKPYHEHIKRLLERNRL
  320-  340 (31.74/24.22)	ELKLLEKLVVSVRNLIERDSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10566 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GQRMQNPRMISVPTTVTPQHLHRQQRYGMTMMQPG
2) LLTMSDALSRLPPEVQQMAQQQINAETNAEKK
3) NTQMVRMGTMQGGPVPYPAQSVSLQTGMGQMGPTQVSVQRMPNHYMASGMSGPQSMQYQSQDPGNVQNYNSQQQITLTQPSSVGPTVQQTSSLHHKGPNSVPSAIYTQHHPESAAPAHSTTGNKNDKSSDEPLYSQ
14
69
141
48
100
276










Molecular Recognition Features






MoRF SequenceStartStop




1) LYSQKLEL
273
280