<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10564

Description Uncharacterized protein
SequenceMVHSDETIDCIAGHMLIVGRSICSMSDQIVRMRGSIQEQMQRSRGKMGRSIKGLRRVQLWQSEEEVLDWTVRSDRAGGGSGSRIATRQALEISVRSCDLQRAVARAKKRCMQQQHPAAASNSGLSAVVPTVESTTVTVVDRLKHQLLQAYDNGDTEQATDVIIKLEKSNLTKELLEMTRVGAVVNDIRKKVAQSAPELSKRCRTLIKCWQKLAEPRPTSSDSSSTNGTPSYASPVIRKGLTPGTPARGPRVICGGNLRLTPAGNSRLTPLSSSVLTPSASSGSRSTVASPTVSNGRTVTLYQRSGQAMPGNSTEFGTIRKSHTIGADLAIKAVESSLLPSGEIVRNGKRKGGSIATSDIGITNGLSATKRLHYSSASVSPAIPHQSLLAARRADVKSTSELVAQLTENLPGYLAINISQSQYPTGNEHGDNEGQANVDTGQTSRTPILFSLQTEASKKKEKRVRSKKDKEKEGRIKDQFIADEKVVAVGSGKSTVGNAEPVTCSIPNRPNSSPSTSKMVVPTRNGKYDWYAMLPSLETLRNREHFRSKPSSSQRKSYIMNVLGREVLALPYIDVGLPDFLEYQYPKPERFYAEENFTYGAPRPN
Length604
PositionUnknown
OrganismLoa loa (Eye worm) (Filaria loa)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Loa.
Aromaticity0.04
Grand average of hydropathy-0.533
Instability index48.71
Isoelectric point9.85
Molecular weight65676.64
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10564
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     173.80|      51|      53|     215|     266|       1
---------------------------------------------------------------------------
  215-  249 (54.01/21.70)	...................P.......RPTS..SDSSSTNGTPSYASPVIRKGLTPGTPARGP
  250-  305 (72.68/35.26)	RVICGGNLRLTpAGNSRltP.......LSSSvlTPSASSGSRSTVASPTVSNGRTVTLYQRSG
  484-  525 (47.11/18.27)	KVVAVGSGKST.VGNAE..PvtcsipnRPNS..SPS.....TSKMVVPT.RNG..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.33|      42|     270|      71|     158|       2
---------------------------------------------------------------------------
   20-   66 (60.65/55.49)	RSiCSMSDQIVRMRgsiQEQMQRSRgKMGRSIKGLRRV.................QLWQS.....EEEV
   95-  158 (54.68/56.07)	RS.CDLQRAVARAK...KRCMQQQH.PAAASNSGLSAVvptvesttvtvvdrlkhQLLQAydngdTEQA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10564 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AEPRPTSSDSSSTNGTPSYASPVIRKGLTPGTPARGPRVICGG
2) GNSRLTPLSSSVLTPSASSGSRSTVASPTVSNGRTVTLYQRSGQAMPGNSTEFGTI
3) NISQSQYPTGNEHGDNEGQANVDTGQTSRTPILFSLQTEASKKKEKRVRSKKDKEKEGRIK
213
263
416
255
318
476










Molecular Recognition Features






MoRF SequenceStartStop




1) GKYDWYAML
525
533