<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10559

Description Uncharacterized protein
SequenceMAAHPVGVSPFPQPPEYARQYTDANVAKKNVLPPPAVPSEFTVFGEEYNFEEEMIRSLQSQKMQQLFSSNGDWRSELKKLNRSTVAAFLDLLDILIRCPNHPERLEKINNLRLLFINMHHLINEYRPVQARDALQSMMKLLIKTIEEVTSRFRTYLAMGHEALNQVIDEVPPVLSASPVLNTEDMNIGESMEQRVGTMEGAVTKRRSSYDEARKTALSRREAWRRDVMLCELLDNMSDTDSERRLSPSTNENPMFLLQGRIYVCKRCKRELNSAYGNIEKLSTHICIGKMPESSRRYGSIHIPARNSRHPLLCAECHKRFQTIQELYLHLEVCIIESFENEAVNVFSSMPSLTESTTVFSLTTHAGITAKGDDPPILIPETNNSASTSKSTNLPLSANCKAECSPAHKIPFELENARILESPGGLKIYVSIEKQSGQESDDVINGNDSYNTHGSNATNCKRKVIGAPASANDDDIYRPKMECPTCGLVLYKHNFGTHYRIHTGELPFVCTYCQKRFRTTSALKVHVRAHTGEKPYSCPKCSYCCITKRNLDRHIINNHVREGERRGPRERRSRYRRDEYSVIIDDIEMSTAEESEKIDHHYVISPAEIESKVVVEGKANDEMEGSDDNRQSVDIPVLPLLTL
Length642
PositionMiddle
OrganismLoa loa (Eye worm) (Filaria loa)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Loa.
Aromaticity0.06
Grand average of hydropathy-0.551
Instability index68.56
Isoelectric point6.54
Molecular weight72849.89
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10559
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     219.93|      57|     163|     251|     316|       1
---------------------------------------------------------------------------
  251-  316 (101.03/78.30)	ENPMFLlqgRIYVCKRCkrelnsAYGNIEK..LSTH....ICIGKMPESSRRYGS.........IHIP.ARNS.....RHPLLCAEC
  420-  485 (69.14/38.88)	ESPGGL...KIYV.............SIEK..QSGQesddVINGN..DSYNTHGSnatnckrkvIGAP.ASANdddiyRPKMECPTC
  535-  574 (49.75/25.17)	...........YSCPKC......SYCCITKrnLDRH....IINNHVREGERR.G.............PrERRS.....RY.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.44|      48|     170|     151|     200|       4
---------------------------------------------------------------------------
  151-  200 (75.46/62.80)	RFRT....YLAMGHEALNQVIDEVPPVLSASPVLnTEDMNIgESMEQRVG.TMEG
  319-  371 (72.99/50.53)	RFQTiqelYLHLEVCIIESFENEAVNVFSSMPSL.TESTTV.FSLTTHAGiTAKG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.70|      10|      25|     497|     506|       6
---------------------------------------------------------------------------
  497-  506 (21.75/13.41)	HYRIHTGELP
  525-  534 (20.95/12.67)	HVRAHTGEKP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10559 with Med7 domain of Kingdom Metazoa
Unable to open file!