<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10558

Description Uncharacterized protein
SequenceMEKESIVERQEQKPVMGDTQCDKYNLVDFSLEEVEEEIRLEKIRQTSLKFSWDYLSQLLRRNLMEKRFVLSADDKEDLMQAAADMRKHMPSDSDRDLSTHLRHLAESLSSDFQAHPGYKIRNADFSLEIAVSADGQQITSCSVSWFGERAVEAQALRLYVSRNRWDLVHTALTTMFHLVPSDLSRDEKIYCLRSLEYAEKDLLNMSGSAPSVFEQINGSILGLCKPRTESTPFTIYPFVEPVVFLDAASGVIISPTDEQVLYDVEPYLQLCIVSSSTPNFFSDTILFAHGEWRNAVSGRQLPAAFCLRFSRPIIFSSAAIKKLSKIASVQLNVEGSYNLYQYLLNENEECHDLFVRLPGCSTQHYIFDDSMTSSQEDGILRQIPFAHLQDVVFLVSIIRTQLAHNAFFESLVRAHSRSACVDENVVDIHIASSYIDCFDLQFYLKKNLFIARVAVSPSKINVSLECVINGAVLPESQHATAILAKSWSLAVMMRSVLRRGGAISLAALEKPFVMNENVDNNCDVKISQSWLFVPNIMDSSINYNKTEHEYVVDERINLNCSHDSNTLGRQSPLSLLALFKELEKIEELIPPQKPMNGAQQCTAPPRNEMLAPRTNRIHSENTMTINAFSVLDAICDMAASIDDGESNISEHSSHSSTSQRLRPQIPPQSPSPASERYRTSQAGNFSQLSPLDIARQRLAQQAPMSNPTDVFEFDDPPRMNSAGPMGTSAQQFHFPEAGQSPYSFVAMQSTRGPLSAQPTLKRRGRGRKAGNIGDRMLDPARPILDQNTGLMFRGMNIPTRKPRGTSTARRPRRPRKAAHMPASPAHSHQFAVNRPMLQRSFSEMPAYPSQMPTVSLSQENRSEASEFDGTEESSDDETDPPPPVCTTAMPQSSPQLTASNSTSIPQTTTVGNHPSSSATLSFVNKSSSLTAGLSSISSSSPATELAPPSSSPAAISNSSMQSAGLLAHKARKGSLEAVVGKLHCKTTPANISGSTTSNPYLASDLYDDESEPVIKPPEPVSTKRDSPSISTSSPGARMSPNLAKMNAEQPGYGSELKIMIKLKQQASARPSTGPSQFSSGGVPPLVHLIFFLNLFEFFTSIMDNSLPLQIHFTVAYFFPEIHVLNRSMRLIGQPPSSSRSKEEKALLRQKQLKEKNRSAPDERARKAGKRERKGELNSSSGSKKLKIDRPLNEQKTTTAVSPKVEFPQALAFASLKNFKIPKVMENEKCESPTPTTTTTPAVATSSSSGTHLNVGQNSGCSTVQVVSSTSLSATTTITPATTTPSSSSSAGTSSIFPPKPKSILKSPAEPPPPSLFRGMGGMPPMLPGRRPLLPDPRNVMHHPPRNQFRPLVALPRMIPSVLSGANFMPPPSSSGRWMALAPQRQRSPRSSPSEQSASSSGLSDTAAAMSKMQDSPTEALKIVADDE
Length1427
PositionMiddle
OrganismLoa loa (Eye worm) (Filaria loa)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Loa.
Aromaticity0.06
Grand average of hydropathy-0.415
Instability index62.89
Isoelectric point7.97
Molecular weight156627.45
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10558
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     518.84|      90|      91|     644|     733|       1
---------------------------------------------------------------------------
  553-  642 (54.15/20.53)	.DERINLNCSHDSNT..LGRQsplsllalfkelekieelIPPQKP....MNG.AQQC.TAPPRN...E.................MLA.......P...RTNRIHSEN.........TM...TiNA...FSVLDaicdmaasID.....................
  644-  733 (157.89/75.78)	GESNISEHSSHSSTSQRLRPQ..................IPPQSP....SPA.SERYRTSQAGNF..S.................QLS.......PLDIARQRLAQQA.........PM...S.NP...TDVFE........FDDPPRMNSAG..PMGTSAQQFH
  735-  828 (109.73/50.13)	PEAGQSPYSFVAMQSTR.......................GPLSA....QPTlKRRGRGRKAGNI..G.................D.R.......MLDPARPILDQNTglmfrgmniPT...R.KP...RGTST........ARRPRRPRKAA..HMPASPAHSH
  845-  921 (67.44/27.61)	...................PA..................YPSQMP....TVS.LSQENRSEASEFdgT.................EESsddetdpPPPVCTTAMPQSS.........PQltaS.NS...TSI..............PQTTTVG..NHPSSSATLS
  932- 1019 (71.20/29.61)	GLSSI....SSSSPATELAP....................PSSSP....AAI.SNSSMQS.AGLL..AhkarkgsleavvgklhcKTT.......PANIS......GS.........TT...S.NPylaSDLYD........DESEPVIKPPE..P.........
 1020- 1085 (58.44/22.82)	............VSTKRDSPS..................ISTSSPgarmSPN.LAKMNAEQPGYG..S.................E..........LKIM.IKLKQQA.........SA...R.PS...T..............GPSQFSSGGvpPL........
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     145.95|      30|      30|    1173|    1202|       3
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 1132- 1160 (28.91/15.00)	.GQPPSS...SRSKEEKAllrQKQLKEKN.........RS...AP
 1173- 1202 (47.31/30.03)	KGELNSS...SGSKKLKI...DRPLNEQK.........TTTAVSP
 1203- 1244 (31.09/16.78)	KVEFPQAlafASLKNFKI...PKVMENEKcesptptttTTPAVAT
 1251- 1279 (38.64/22.94)	HLNVGQN...SGCSTVQV...VSSTSLSA.........TTT.ITP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     208.77|      67|      89|      46|     117|       4
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   46-  117 (100.25/76.74)	TSLKFSWdYLSQLLRRNLMekRFVLSaDDKEDLMQAAADMRKHM.PSDSDRDLSTH.LRHLaESLSSDFQAHPG
  139-  207 (108.52/64.80)	TSCSVSW.FGERAVEAQAL..RLYVS.RNRWDLVHTALTTMFHLvPSDLSRDEKIYcLRSL.EYAEKDLLNMSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.25|      23|      82|    1280|    1302|       8
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 1280- 1302 (39.92/17.07)	ATTTPSSSSSAGTSSIFPPKPKS
 1365- 1387 (44.34/19.79)	ANFMPPPSSSGRWMALAPQRQRS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10558 with Med1 domain of Kingdom Metazoa
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