<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10528

Description Uncharacterized protein
SequenceMESNSEGSSTPQEEEVVPMEATEAAGPSEPKLLAKRKGVDLILEANNDWKIQEIGFDGVERYLQPETFTDYVGKLARRVEWMKLVDSKSPYENSKVEPEEDEDERLAQVGKHGTNVELVTPESGPWSSVAKYLHESLNQLNILLDDMCVMKSTDYMKALTVLDPITVQEPTPEYINTNRGTQWIWKRRALQEAVQVLDIAQKQRQRAMSNLGLSVEYIAHLQRTKFFEELREMREIWRVRKTGDYIYGDLGYHIFGWKYDTPHIFDISRRTLCSKFETSNLSIIEVSVPKDLARRSMLCVTIVRDDVDAGQLIRDPEEAAKYAYSFREVDAEKIKELHWKDSLKWAQNTLILRDTFNNLCKEAIQLRNSPSIIRDNVMMIRLFDEYMLRFELQWFPFQPGELKEEGDVYLNRVLREMIIGFQCTKFVRPQFFCSMPVTHLPESLDLRGCQAYDTKEIEDRAVRPRAILTRMINVASHRALTTMVTDVAERVCRPNLDPTVQYKWLHCGRESSTMMFVMTSKDYEQYMGNVRNVFFAHVSCEGVEIETKEGVRLKCDRDAARVLYACQYVVCCYSVTMVSIISRNQWMTPFQVMYANVYALDEKGDPAPNIILCNQAATRSVLFVFHVGADPEISIRRFVVNEETAKPEEHQWKRLNYAKLYGTTLCKKIDALLSYIRDC
Length679
PositionHead
OrganismCaenorhabditis tropicalis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.09
Grand average of hydropathy-0.395
Instability index47.65
Isoelectric point5.63
Molecular weight78759.32
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10528
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.22|      39|     312|     315|     362|       3
---------------------------------------------------------------------------
  315-  362 (47.06/61.08)	DPEEAAKyAYSFREvDAEKIKELHWKdSLKWAQntliLRDTfnNLCKE
  630-  668 (71.16/48.08)	DPEISIR.RFVVNE.ETAKPEEHQWK.RLNYAK....LYGT..TLCKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     348.15|     114|     364|      27|     155|       4
---------------------------------------------------------------------------
   27-  155 (159.26/154.20)	PSEPKLLaKRKGvDLILeaNNDWKIQEIGFDgVERYLQPETFTDY.VGKLArrvEWMKL.....VDSKsPYENSKVEPEEDEdERLAQVGKHGTNVELVT........PESGPwSSVAKYLHESLNQLNIllddMCVMKSTDY
  396-  523 (188.89/125.87)	PFQPGEL.KEEG.DVYL..NRVLREMIIGFQ.CTKFVRPQFFCSMpVTHLP...ESLDLrgcqaYDTK.EIEDRAVRPRAIL.TRMINVASHRALTTMVTdvaervcrPNLDP.TVQYKWLHCGRESSTM....MFVMTSKDY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10528 with Med17 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MESNSEGSSTPQEEEVVPMEATEAAGPSEPK
1
31










Molecular Recognition Features






MoRF SequenceStartStop




1) PQEEEVVPM
11
19