<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10524

Description Uncharacterized protein
SequenceMSDESDTEHEEAMTCADTYNAFIAKKRAKLAEHEAEKTSLLKEPVFAKPENPKRRVTIKEEVDDNSYNSSMGTSKPFNCHVKQEPMDYDEYGTDPSTIELPPNPPKSPEQEPEDQDAERTEDQEEEQEDEADENEDESRPPTPVEYIPIPLKPLYSSPKKDPKDDEKYKYMRIGRKRKLREKISGRYGAMTYPFWYQQGGVSVDPENTDVLDFSNPTPPEQAPAEPLIEFELSPSASPAPVSENKDGENGEKKDDEKKNGEKKDGEAKSVADKSAEDHTNDLDIPMNPEDVEVVEAEDKSTEEQAVSEKRKSDRKESSPAKEVSAEPSTTTAETEATKESAPVDETAKASTEDDAMETEDFDLNSLLMDLADTAKEDPMEVASPAADSNAKSDDKEASTSAAEPMEVDKPEDGENPAEEAEDDCMIIEQEEVHVTEDEVMLIREVKGDQNPENDSAEKTEQEGKESEEKEKEKEAVIEQPSVEKEVVEPEPERIYTAEELEKMKTEKEIDDLVTITTEAFKQKIESDEKWQTSSFHPGFKEWDQNQKTRGSLHLISTALQFLACAVPECFVWNNLVVTKRERRHRMLPQLCGSPLDYLPCELYELPIMEGNESIGELLRVRHQEIIRRSQAAEEKWIPHGADVLKYGRIIDTCVDVLGIMDNIDVEKPRAIENAALRLFHFREKFAKGEALLRTKLMFKWCITEEREGSFRAVYIAKLLRFGMDQNPEKTIGGWEVMDLFFSFMYAEGPKYGDPMYQAHFDSTAAIMIEMLREKIFSITDILQELEKNLDIDYSAPLMWRQRKQKIPKISKRHRKAEVIDDTKLVHFTSTYTPKRLFMGKKMDLLERMLIILPQLEVNEDSDEFRIRRNLLFGLRPSGNPYFRRIKSIYKSISKELETKLHIQFDKSTKVTTAHKKINQPRLDDLLRQYRAQTYHDQNIIMERIVYSYIDGIAKFLKRGHDDVPAPDIANIICEMYEYSMDITSIFDFFEKIVPFLKPVDHKILHCRMDVLPDMFHTEMAFIFVSFFMKHWQRFLLHPRACSIVNQLYRLIEDMIRADDHLITCWGRTVAIFCFHARKYIANAGLQTEPFVAEDKHFWRVFPNTQKHDIDMNYFNDQFSGIKLTLRGGALRYDSYNDFKWVVNNMKPSLKKKNPVKHPNARYSFVIRAFREARQHGRNFDRINELANYCANVTANDPPLSEYWIAAIKGLCCLSIDQSYPFKEMAHYIDISDCSTHYSMTTFITCLAGKSAFYIPRLLSELTKNIFPLMLRHDGRLTSHKTRDVKRKVTSKTSESRTLSEAEPGVCLCLLIISGLCCAGDEPFGLSVHYRGIERKKKRFNNTADERIMHLFHWFEMDNAMFRTLGQISQLLEALQSRCRDASLVLPKTFPMKHPHKYEQQESYREKAPYRPQFLFNIAKAVFFTICEQDWVTLRMFRFIKTKNMEAFNQDKLKQNCLGQQMLRIALRRKTERENVHKLFEAHKISKKVTVDKVLSFMTLWNFRATLFDLMLMIKEISPDGNTRHAQQGAIAADALMSEIGKCCRDMFVYAYKNKINMPIVKNFSEFRFSDVSKYWLIAPLVRMCPKPINIPPQYANTTVGTVAAKFLREAAFLMDTPPTTPKERLLQCSWAMSRIPFINMILTCLRCEKTQQSKDVFLQSLYQQLQREVLRDHHRRSNWTNRREHRDCTVLRMTLISHIYKEILKPTHVEQWGILMFQLMFHGIINPSRDKHVYDNCFDMLQHMILWTLVDGDSMNIHDRYGSIRVRWPQYAGLVKKMKKETHDRYTDATRANLFRFLPIGKAQLPTVSYKKYQKKMKPVHSMKKFMSNGGLKNGKYVYVPEEKMKTNSFDHTLDLPDGLQKGGWRFRMFQTTRLDKVGKHALSGIRILLPHKHQAEFCRPQMAMFDNMYDDSYLLPPEIEITQTIEEPVIAGEEDVDVTKKTAEEEKDGEKTDEAKKATDKKKGDEEKKNDKESEKTAEKENETEKDKSAEAAKKDDVTPIEIEKEKNTAEVVPVVPVVASEANKEMDTSTPKRKSAPVTRNSPATRGRGGGRKRNSGARGGPRAKRTNSRAQPKEDPAQANAPGWAGGASSSNTSGSNYHSLMRNNPPPMSNGSSDETKANIRNLLNRKQEKRNSIADANAAAAAAAAASANASAANQPGTSATISHVPTSMQPIQQLPGMVTLQHQNPMGQPGMGAMMPSGNPMMNPPHQTAPPPYNATGEMNRMHSFGQPMFAVPNPGPLARGPLGLPSTANCSAEERERIMKQQAYEKLEQQRILLETQQRNRESRELMERAQEEKKRAENENRRLMEEKLAREREEQMREERRREEARYMEQQRLEQQRLEQQRLEQQRLEQQRLEQQRMEQERLRKEAEERMRREAEERARQEAERERLRREAEERERERERLRMEQERIQREMEEKARREREEAMRLEALERERQEKMEQERIRDAERIREAAAAREAAAREAEAHRQRMEQQQRMNQQNQYMNQQAPPYGQQPQGQPPSYQQSSYQNPTGYQQGQQSNQPPSYQQPSHSHQSMQQNQQHQPPAYQQGGSQMQMNMQQQQNRQQQPSGQQNFGGSTGMGQQNQSYPGYQQQMGQQGQQSMSQQQQQPRHPFSAQPEMQAGGSTMLMHTKPTETHTQQYQHTQNQMAMNQKEKEKQYFQAKNAQSGQAQPAQPQQPARFGDATAGNTSNFGRNMSFGQQKAGSSEFAAPAPVASTRLLPGPTINPTPLQLAGMQNAAMQSSGMQNYQQQPVLGQPGPMQPGGSGSQQQQSQPQQQSAAQQGYLPAVRSTPTKSDMGMRGGSIGTQPPQNRMGQGSGSQGFGGQGQPAGYQQNQQQAQSGYQQQGSQYPGQNQGQHQQSQNVNQSQNAPQNITPGQYGRTNPEGAYNQQSGYNQNYQRPEAPAANQNVSNPWGQSANQSQNQMRPQQPAQTQQQPGQFARPDQQQYQQAQQSKNPMGQSGSYGSGGFSGQQQGYDQQGTQNPHHQHQQQNPQSSQQYGQQQQASSQNQAQQQQQNRYGGMSGYGGSTGSSSNILNQSMEESGLNQGYSGSNASSQQSGSNQMQQSGYGAQANQMQQQRMGQPGMAQSGMGQTGMGQSGMGQQGMGQQGMGQPGMGRSGMGGMGQPSQQQQQPQQPQQQPQRPMNPMGGAQLPPYSMGQPTAQQPGQQSQDQYRRMQMQQQQQQAQQQAQQQAQQQAQQQAQQQAQHNRMQQQQPGVQQQTPGGYSNQVQYPPIQHRGQGPQAHGMGTMGAQQQAQQPGANQYYQQQDQRMQQQQQQANQQQQHGYGMGQYPNQQQHQY
Length3304
PositionKinase
OrganismCaenorhabditis tropicalis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.07
Grand average of hydropathy-1.024
Instability index55.51
Isoelectric point6.63
Molecular weight377434.34
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10524
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     153.65|      22|      22|    3085|    3106|       1
---------------------------------------------------------------------------
 2544- 2565 (33.45/10.15)	QNQ..........QHQPPAYQQGGSQMQM.NMQ
 2928- 2950 (26.49/ 6.12)	QMR..........PQQPAQTQQQPGQFARpDQQ
 3072- 3103 (36.37/11.84)	GYGaqanqmqqqrMGQPGMAQSGMGQTGM.GQS
 3104- 3126 (28.16/ 7.08)	GMG.......qqgMGQQGMGQPGMGRSGM.G..
 3127- 3155 (29.18/ 7.67)	GMG...qpsqqqqQPQQPQQQPQRPMNPM.GGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.40|      22|      22|    2385|    2406|       2
---------------------------------------------------------------------------
 2740- 2762 (27.15/ 6.50)	MQNAAMQSSGMQ.NYQQQPvlGQP
 2834- 2854 (30.89/ 8.58)	AGYQQNQQQAQ.SGYQQQG..SQY
 2988- 3006 (27.35/ 6.61)	PHHQH...QQQNPQSSQQY..GQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     118.80|      22|      22|    2385|    2406|       3
---------------------------------------------------------------------------
 2309- 2330 (27.87/ 8.26)	RRLMEEKLARERE.EQMREERRR
 2394- 2414 (28.50/ 8.64)	ERLRREAEERERErERLR..MEQ
 3179- 3199 (34.34/12.18)	RRMQMQQQQQQAQ.QQAQQQA.Q
 3200- 3217 (28.10/ 8.40)	QQAQQQAQQQAQH.....NRMQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.08|      20|      22|    2490|    2511|       4
---------------------------------------------------------------------------
 3156- 3171 (28.84/ 6.67)	QLPPYS..MG...QPTAQQP.G
 3261- 3281 (23.29/ 8.92)	QQPGANqyYQQQDQRMQQQ.QQ
 3282- 3299 (29.96/ 7.23)	Q.ANQQ...QQHGYGMGQYPNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     103.84|      21|      22|    2490|    2511|       5
---------------------------------------------------------------------------
 2490- 2511 (40.67/18.21)	YMNQQAPPY.......GQQPQgQPPSYQQ
 2514- 2534 (35.22/11.11)	YQNPTGYQQ.......GQQSN.QPPSYQQ
 2586- 2612 (27.95/ 6.99)	.MGQQNQSYpgyqqqmGQQGQ.QSMSQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.39|      18|      23|    1948|    1970|       6
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  245-  265 (24.48/ 6.81)	KDgenGEKKDDEKKNGEKKDG
 1948- 1965 (32.09/13.05)	KD...GEKTDEAKKATDKKKG
 1973- 1990 (26.82/16.33)	KE...SEKTAEKENETEKDKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.15|      21|      23|    2336|    2357|       7
---------------------------------------------------------------------------
 2336- 2356 (40.04/18.06)	MEQQRLEQQRLEQQRLEQQRL
 2361- 2381 (32.11/12.63)	LEQQRMEQERLRKEAEERMRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      95.86|      23|      23|    2083|    2105|       8
---------------------------------------------------------------------------
 2043- 2075 (21.71/ 7.89)	NSPatrgrgggrkrnsGARGGPRAKRT...NSRAQP
 2083- 2105 (41.99/22.75)	NAP.............GWAGGASSSNTSGSNYHSLM
 2108- 2128 (32.16/15.55)	NPP.............PMSNG..SSDETKANIRNLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     292.42|      90|     104|    1207|    1303|       9
---------------------------------------------------------------------------
 1207- 1303 (142.20/101.97)	IKGLCCLSIDqsyPFKEMAHYIDISDCSTHYSMTT......FITCLAGKSAFYipRLLSELTKNIFPLMLR.HDGRLTSHKTRDVKRkvTSKTSESRTLSEAEP
 1312- 1408 (150.22/88.99)	ISGLCCAGDE...PFGLSVHYRGIERKKKRFNNTAderimhLFHWFEMDNAMF..RTLGQISQLLEALQSRcRDASLVLPKTFPMKH..PHKYEQQESYREKAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     146.88|      23|      23|    3024|    3046|      11
---------------------------------------------------------------------------
 2567- 2585 (32.65/ 9.84)	QQNRQQQ...P..S...............GQQNFG.GSTG.
 2776- 2811 (26.38/ 6.35)	QSQPQQQSAAQ..QgylpavrstptksdmGMRG...GSIGT
 2951- 2973 (32.43/ 9.72)	QYQQAQQSKNP.................mGQSGSY.GSGGF
 3016- 3035 (28.01/ 7.26)	QQQQQN.....ryG...............GMSGYG.GSTGS
 3235- 3256 (27.42/ 6.93)	QYPPIQHR..G..Q...............GPQAHGmGTMGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     141.05|      23|     132|    2676|    2698|      13
---------------------------------------------------------------------------
 2188- 2210 (34.26/15.99)	HQNP..MGQPGMGAMMP......SG................NPmmNP
 2211- 2238 (25.49/ 9.42)	PHQTA..PP.PYNATGEmnrmhsFG................QPmfAV
 2680- 2698 (28.86/11.95)	PQQPARFGDATAGNTSN......FG......................
 2814- 2833 (26.39/10.09)	PQN..RMGQG.SGSQG.......FG.............gqgQP....
 2875- 2910 (26.05/ 9.83)	PQNIT...PGQYGRTNP......EGaynqqsgynqnyqrpeAP..AA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      57.36|      12|      14|    2423|    2434|      14
---------------------------------------------------------------------------
 2423- 2434 (21.42/10.05)	EKARREREEAMR
 2439- 2450 (18.21/ 7.35)	ERERQEKMEQER
 2465- 2475 (17.73/ 6.95)	EAAARE.AEAHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.19|      20|      23|    1698|    1720|      19
---------------------------------------------------------------------------
 1698- 1720 (33.04/25.39)	HiykEILKPT...HVEQWGILMFQLM
 1722- 1744 (32.16/16.70)	H...GIINPSrdkHVYDNCFDMLQHM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.40|      15|      23|    1747|    1761|      20
---------------------------------------------------------------------------
 1747- 1761 (30.37/22.87)	W....TLVDGDSMNIHDRY
 1768- 1786 (24.03/16.23)	WpqyaGLVKKMKKETHDRY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.03|      24|      26|    1813|    1837|      24
---------------------------------------------------------------------------
 1813- 1837 (40.36/37.31)	Y..QKKMKPvHSMKKFMS.NGGLKNGKY
 1839- 1865 (34.68/25.22)	YvpEEKMKT.NSFDHTLDlPDGLQKGGW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.29|      12|     141|    2021|    2032|      27
---------------------------------------------------------------------------
 2001- 2012 (18.29/ 9.68)	PIEIEKEKNTAE
 2021- 2032 (20.00/11.35)	ASEANKEMDTST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.30|      25|     147|    2893|    2921|      29
---------------------------------------------------------------------------
 2644- 2658 (22.25/ 6.26)	.......QQYQHTQ....NQM...AMNQK
 2893- 2921 (43.77/21.20)	NQQSGYNQNYQRPEapaaNQNVSNPWGQS
 3044- 3071 (39.28/18.09)	MEESGLNQGYSGSN.assQQSGSNQMQQS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10524 with Med12 domain of Kingdom Metazoa
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