<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10492

Description Uncharacterized protein
SequenceMIDARFRLELEKRRANVEDQFEFENCKVGKGTYGHVFKARMRRPEQGGKRYFALKMIETAGFTMSSVREITLLRELNHPNVIKLQQVFLTPERKVWLLFDYAEYDLWNIIKTHRDCRKNKTPFHVERRMLKSLMYQILEGINYLHSNWILHRDLKPANILVMGDCDNLLDRGRVKIADMGFARVFYNPLRSFYDVDPVVVTYWYRAPELLLCAKHYTKAIDIWAIGCIFGELLTNEPVFLSRDDDLKAQTPYNQEQLGKIFNVMGYPSEAEWPDLKNMPEYLKLQAEFRRNSFANCSLKKYIESKKLPTDNQQFDLLEKMLTMDPTRRLTAEDALRHPFFKEPPFPTVDVFNGDKIPYERRQFMKDEDVVRGPLQQAPEMVAPPLKKIKTEALTQPQPCLPQAPPTYMQATQNPQQLHQHPANPSMIPLNYPQHPQQPPQQHHFNVRQVKPEQSNPQVQRVQYHPNQMQMHPQQAQNIPLFHQHQQVRMAHPQQQQQVQGMPPQMVQRQFIQQMPQGLIGTQPNMMPPGTIINPNQVQMRAMPPQMPQNMYQPPRYQ
Length557
PositionKinase
OrganismBursaphelenchus xylophilus (Pinewood nematode worm) (Aphelenchoides xylophilus)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Tylenchomorpha> Aphelenchoidea> Aphelenchoididae> Bursaphelenchus.
Aromaticity0.10
Grand average of hydropathy-0.702
Instability index56.65
Isoelectric point9.22
Molecular weight65572.96
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10492
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.97|      18|      18|     435|     452|       1
---------------------------------------------------------------------------
  435-  452 (38.34/14.46)	PQQPPQQHHFNVRQVKPE
  456-  473 (29.61/ 9.66)	PQVQRVQYHPNQMQMHPQ
  523-  540 (24.03/ 6.58)	PNMMPPGTIINPNQVQMR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.47|      35|      50|     288|     325|       2
---------------------------------------------------------------------------
  288-  325 (54.04/43.06)	FRRNSFANCSLkkyIESKKLPTDNQQF....DLLEKMLTMDP
  340-  378 (56.42/36.32)	FKEPPFPTVDV...FNGDKIPYERRQFmkdeDVVRGPLQQAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10492 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RQFMKDEDVVRGPLQQAPEMVAPPLKKIKTEALTQPQPCLPQAPPTYMQATQNPQQLHQHPANPSMIPLNYPQHPQQPPQQHHFNVRQVKPEQSNPQVQRVQYHPNQMQMHPQQAQNIPLFHQHQQVRMAHPQQQQQVQGMPPQMVQRQFIQQMPQGLIGTQPNMMPPGTIINPNQVQMRAMPPQMPQNMYQPPRYQ
361
557










Molecular Recognition Features






MoRF SequenceStartStop




1) MYQPPRYQ
550
557