<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10470
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MTQLPLDELQWKSPEWIQSFGLRTDNVLDYFSQSPFYDRTSNNQVAKMQQQFAQPRQPVRTPKPSDTGVTAVPGTDIDPHRQAILSTYLVHSMLDQELRKLKGIEYILAYVREPDFWVIRKQNRTGPTSVEPLQDYYIIGANVYQAPAAAKIVQSRLLATNFHLSRALASLRRMSQFQPSQGANFIPTPTTPGTRPRGADAAPASAPASAAPTVVTSAGSAGTAGPGTANTQSILTGSTDPAANMPAHADVITRELMDKLLVTSMKSNPVYL |
Length | 272 |
Position | Head |
Organism | Lachancea fermentati (Zygosaccharomyces fermentati) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Lachancea.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.361 |
Instability index | 46.18 |
Isoelectric point | 9.30 |
Molecular weight | 29695.26 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 PIRNR:PIRNR013286
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP10470
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 72.17| 23| 57| 52| 76| 1
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52- 76 (39.15/23.81) FAQPRQP....VRtpKPSDTGVTAV.PGTD
108- 135 (33.02/14.46) LAYVREPdfwvIR..KQNRTGPTSVePLQD
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 108.45| 33| 36| 182| 216| 2
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182- 216 (54.30/28.51) GANFIPTPTTPGTRP..RGADAAPASAPASAapTVVT
219- 253 (54.15/23.53) GSAGTAGPGTANTQSilTGSTDPAANMPAHA..DVIT
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