<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10464

Description LAFE_0D03554g1_1
SequenceMNQGKPKQAVRLKMEEMEDKLGSDSMYKDSVLQDIRKAKDSILPMRLRFNDLINTIASIDKTQGKSSQEKFTMIRAKVLELSTEIQSFCGEYHKLQPVFEAMQQYSKEGKTSKKFTPLETLRHVNEVTINTQSKPPNATSPSNARLNKSNVNTPASNVPTPSAGGNVAVKKPRKPRQKKNSIPGAASIPLQASPPTNPSQILSNMSPMNMMSSPMSTMSPVNGSMNLPYNGSASISTAPKPQSQPQRHIPSASQQLNMNNITPANILNMSMMEQNPMQAPSSQQSQLSQPQHQSSNSLDLNSLDLNNIDLASLNMDFLQ
Length319
PositionTail
OrganismLachancea fermentati (Zygosaccharomyces fermentati)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.03
Grand average of hydropathy-0.717
Instability index67.16
Isoelectric point9.68
Molecular weight35081.56
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP10464
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     193.21|      44|      44|     218|     261|       1
---------------------------------------------------------------------------
  159-  183 (30.27/ 7.76)	PTPSAG.......GNVAVKKPRKPR.....QKKNSIP..............
  184-  210 (29.59/ 7.44)	.............GAASIPLQASPP....TNPS.QILSNMSPMN...M...
  218-  261 (82.69/32.39)	MSPVNGSMNLPYNGSASISTAPKPQ....SQPQRHIPSASQQLN...MNNI
  263-  308 (50.66/17.34)	..PAN.ILNMSMMEQNPMQ.APSSQqsqlSQPQ.HQSSNSLDLNsldLNNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.79|      24|      43|      63|      87|       2
---------------------------------------------------------------------------
   63-   87 (35.84/31.92)	QGKSSQeKFTMIRA..KVLELSTEIQS
  108-  133 (36.95/27.37)	EGKTSK.KFTPLETlrHVNEVTINTQS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP10464 with Med3 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) EAMQQYSKEGKTSKKFTPLETLRHVNEVTINTQSKPPNATSPSNARLNKSNVNTPASNVPTPSAGGNVAVKKPRKPRQKKNSIPGAASIPLQASPPTNPSQILSNMSPMNMMSSPMSTMSPVNGSMNLPYNGSASISTAPKPQSQPQRHIPSASQQLNMNNITPANILNMSMMEQNPMQAPSSQQSQLSQPQHQSSNSLDLNSLDL
100
305

Molecular Recognition Features

MoRF SequenceStartStop
1) KQAVRLKMEE
7
16