<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10457

Description LAFE_0C01002g1_1
SequenceMIPSKYTLTPPEDLHPLNFEGSKPIYPDFDPWSHTQLEDKILLNFVSKGYYNSAKVNFESISARSSLQESLPTVSTLLADQLSNVLHIREQDINKISSVALDANSKRVKFNELAGPGFSLPTRVTLTDHRRELWLQEISSPHASLSNISKSIPHGLKRRQVLEQCFTKQIPISRAVWLIKCSYSIEWKILTSKQKHESSDEITNHLYKEWTDNMAHILEKLVFEMTQYYNEPIQLRAWKKKISYYLKLLGNCYTINLLDKNIFHHWLVEFVGKVENFECIPLTLHIMSVFWDGLCQKSESASSEQIFLVNKITEALLYKYYMVSRSKSMINDEQYLINDVKKNSKLKELILAKLKGFILRVFHEQSLEAFIMSNNNWDIYKNCLYEILGVDKQHETGSNKTELKKKLELIVYRNDSLKFNSVLQDNETSDTNISEAFEGSLESLFIKDKPLKLKRVDYGLTTVLDDNSPGDDWVSYVDQKLTRIDQVIQMIMWAIHPSRASHYEGCQLIAKLLLLKINSQNSFQEYNIEDTVWALIFRFAKLSSQEMNTTLVPSRLYQLLNIFIGYGLIKVPTYVRKLISSGILYLSESQDKYFHCELLVNLKIAPLMKSQYNMVLKNVKEYDPSFFENFNYDKLMEMLEVAKSNVLAGDFAFVETVPYSVKVLSSEWYLNFICTPTDNLLEPVDKENIINKLKVFCINMKEFHHFYKWVEFIVYHQLLKDISALECLVDILMFYDKLFPLLINDHILLMKTLLHLYSKELALKDPQSYQVYAFNHFWKFFTRKFPFALEIDGDLQMKLAEVYESEKLRMEKIAKSYSMASELYDQINRSTPSSGSEMNKLESHNFPSLFQKNIKLLLNSNDEGVKYSAKTSMRLLLNLNPSEYNKFMSVFLKRKDFTDEQLKHLISLKVLSFEQINKVLGEPFLLKLLDSTYFDLGLTFELQKHNYIKQNFKDLLNAYQKLRSDNNISLFNLIIIFNTSPARQDQSCNTLYKILKSNDTDCLSTITNLLGFGTKVYPCTGSLECVNNDETDDEGDHTIEELSPVELFEELDFANLWIFQVFTKYYLEILSMNAANDLVFKKHIFDIIDVTGDDLLCSKIFDRISDLTLLERLLCVVEIDFFEKCLSNRDVSLPYFRVIIEIITNLSRKLNKISGGVIAMHDRAFNLLQLCAENFASMLPDELLNSESKLDVYLKVMIVHQQFVFRKCIDGLQTGGPEKDLICHLCKLFGKVGFSLKVKLLLYDILTSLKSFTIYASTRKSHSNMAKININVPKELLDLPPFSISSFMKSDPTDDDSADIHLGIVDDSSTERQIEPKYFIFNKKTLEYDCKLVLKPFHLLINYQEAGNGPFNNTSLSMSLFNASFDKKNPT
Length1371
PositionKinase
OrganismLachancea fermentati (Zygosaccharomyces fermentati)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.11
Grand average of hydropathy-0.182
Instability index39.58
Isoelectric point6.15
Molecular weight158961.59
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10457
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     199.55|      53|     113|     734|     787|       1
---------------------------------------------------------------------------
  734-  787 (91.12/63.31)	FYDKLFPLLINDHILLMKtLLHLY.SKELAL.K.....DPQSYQV.............YAFNHFWKFFTRKFPF
  792-  848 (42.69/23.21)	...........DGDLQMK.LAEVYeSEKLRMeK.....IAKSYSMaselydqinrstpSSGSEMNKLESHNFPS
  849-  897 (65.75/40.17)	LFQKNIKLLLNSNDEGVK.....Y.SAKTSM.RlllnlNPSEY..................NKFMSVFLKRKDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     229.54|      60|      61|     126|     185|       2
---------------------------------------------------------------------------
   67-  120 (49.47/29.14)	.........LQE.SLPTVStlladqLSNVLHIREQDINKiSSVAL..DANSKRVKFNE...LAGPGFSL
  126-  185 (103.72/69.96)	LTDHRRELWLQEISSPHAS......LSNISKSIPHGLKR.RQVLE..QCFTKQIPISRAVWLIKCSYSI
  190-  244 (76.35/49.37)	LTSKQKHESSDEITN.HL.......YKEWTDNMAHILE..KLVFEmtQYYNE..PIQLRAWKKKISY..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.32|      29|     121|    1066|    1097|       3
---------------------------------------------------------------------------
 1066- 1097 (43.10/35.70)	YLEIlsMNAANDLVFKKHIfDIIDVTG..DDLLC
 1193- 1223 (50.22/30.08)	YLKV..MIVHQQFVFRKCI.DGLQTGGpeKDLIC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.76|      30|      40|     397|     434|       4
---------------------------------------------------------------------------
  397-  434 (43.99/46.00)	GSnktelkkkLELIVYRNDSLKFN.......SVLQDNETSDTNIS
  439-  475 (46.77/31.01)	GS........LESLFIKDKPLKLKrvdygltTVLDDNSPGDDWVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.75|      41|     338|     347|     388|       5
---------------------------------------------------------------------------
  347-  388 (70.64/53.61)	KELILAKLKGFI..LRVFHE..QSLEaFIMSNNNW.DIYK.NCLYEIL
  686-  732 (58.11/38.70)	KENIINKLKVFCinMKEFHHfyKWVE.FIVYHQLLkDISAlECLVDIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.55|      28|     121|     489|     561|       7
---------------------------------------------------------------------------
  493-  521 (45.74/95.57)	WAIHPSRASHYEgCQLIAKLLLLKINSQN
 1318- 1345 (50.81/11.02)	YFIFNKKTLEYD.CKLVLKPFHLLINYQE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10457 with Med12 domain of Kingdom Fungi
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