Description | Mediator of RNA polymerase II transcription subunit 22 |
Sequence | MSDRGLLEQLNRITDTLSRSLANLVKNSSISKEGDEDEHGNYNTPESAARTSTSGLMLVNAQTAQLIRGIQDLMVMTRTIREKWLLTQIPDENDESQLELDYKKCSQLLEQWEKEVLG |
Length | 118 |
Position | Head |
Organism | Lachancea dasiensis CBS 10888 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea. |
Aromaticity | 0.03 |
Grand average of hydropathy | -0.663 |
Instability index | 27.17 |
Isoelectric point | 4.68 |
Molecular weight | 13396.86 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 PIRNR:PIRNR007936 |
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi |
Binary Interactions |
Repeats | >MDP10427 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) EQWEKEVL 2) HGNYNTPES 3) LELDYKKCS 4) LIRGIQDLMVMTRTIREKWLLTQIPD 5) RGLLEQLNRITDTLSRSLANLVKNSSI | 110 39 98 66 4 | 117 47 106 91 30 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab