<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10424

Description LANO_0E10066g1_1
SequenceMNRDMYSAQNQASNLYQQSQPTSQTIWQQQMADSKGCNSNSSKPLLMANNNVFSIGPYKKRKDANRVSVVEKYEIIGYIAAGTYGKVYKARKKNLTPNGSTSSSTDSEVSSVPVSKNPPPNGHEALDVNSINKSTRVQDPSTSSMSINAQQEMHSDHKVQSSKKSHDNNTSGSIMIGPPLMKLPSLYAIKKFKTEREGVEQLHYTGISQSACREMSLCRELRNKHLTHLVEIFLEHKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSILWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFHNMVQTLYTGDKVVVTIWYRAPELLLGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMDSKKSVPFQANQLQRILEVLGSPTEKSWPDIYKYPECEQLSKFPRYRDNLPVWYHSAGGRNKEALELLYQLLRYDPITRIDAVDALEHPYFTNEAPTVCENVFEGLNYKYPPRRIHTNDNDIMNISNTKAKATATNPQAIASKNAANASLGGLGVNRRILAAAAAAAAAVSGTNSSTRPGSSTNVTGPLRKKRR
Length573
PositionKinase
OrganismLachancea nothofagi CBS 11611
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.07
Grand average of hydropathy-0.504
Instability index44.90
Isoelectric point9.40
Molecular weight64162.37
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP10424
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.76|      22|      27|     254|     280|       1
---------------------------------------------------------------------------
  258-  280 (37.33/33.06)	SHPEKRLIPPRMLK..SILWQIlDG
  282-  305 (36.43/16.88)	SYLHQNWILHRDLKpaNIMVTV.DG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.08|      16|      27|     131|     147|       2
---------------------------------------------------------------------------
  131-  147 (22.60/16.51)	INKSTRVQDPSTSSmSI
  159-  174 (27.47/15.12)	VQSSKKSHDNNTSG.SI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.69|      17|      20|     515|     531|       3
---------------------------------------------------------------------------
  515-  531 (28.63/17.72)	NPQAIASKNAANASLGG
  535-  551 (26.05/15.54)	NRRILAAAAAAAAAVSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.09|      12|      26|     417|     431|       6
---------------------------------------------------------------------------
  417-  431 (14.48/20.66)	EQLSKFPRYrDnlPV
  445-  456 (22.60/14.47)	ELLYQLLRY.D..PI
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP10424 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) KARKKNLTPNGSTSSSTDSEVSSVPVSKNPPPNGHEALDVNSINKSTRVQDPSTSSMSINAQQEMHSDHKVQSSKKSHDNNTSGSIM
89
175

Molecular Recognition Features

MoRF SequenceStartStop
1) RRILAAAAAAA
536
546