<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10414

Description LADA_0F14598g1_1
SequenceMPNKYLLNPPDNLHSLTADSRKRIYPDFDPWSHTPVQDQIFLEFVSKGYYNSAKVNFESISSRSSLQESLPAVSEHLAEQLSKVMTIREEQVNKIGTNSPDSKSMHTAGSDLCGPGFSLPKRVTLTDHKRELWLQALSSPHSSLADTVKTIPHGLKRRQVLEQCYQKQVPYSRAIWLIKCCFTLEWNTLISKQVSRQHEVSLKLLKEWSESMAHILEKLVFEMTQYYNEPLKLKSWRRRLAYYLKLLGNCYALHMIDRNVFHHWLVDFVVKVENFECLPMTLHILIVFWDGIFGSLPDSENPQQLFLVNKLTEALIYKYYMVSTSKSMINDEQYLINDIKKNKKLGSMITKRISFLILKVFDEQSLEAFVFPSSNWEIYKKCLYEIIPTEIPHENHPYKTDSLKKLELIVYRNESLKFNTILHDPEEHKSGSNNEPNSDLESIFIPNRVLKLKNIDYELTRLLDANAAGDDWLSFAEHKFSRVDQVIQMMLWAIHPSRFHHYEAAELTAKLLLLKLNLKSGLLEYSLEDKIWALMFVFAKLKPQERCLVVKLSRLHQLLNVFIGYGIVKVPTYIRKLISSGVLYLTDSDDKFFHCELLINLKISPLMKSQYNMVLRNVVDVCPKYFEDYNYDNLMALLGESKDSLLTRNYTFFGSVPYSVKLMTSEWYLNLICSPVNGDLLPVTKVDIRDKLMVFCVNLKLYHQFYKWVEFIVYHKLLKDLEALECLVDILIYYDRLFSLLINDHILLMKTILHLYSDKLIWESPESQNLITLGGFLHFFTTRFPMALELDTDLQAKLHEVNEFEKAKIEKVTKSNSRSGPSTFPNEQDLTISSGDDSSSFPSLFQLNLKLILHPKTDDELQTARNNMKALMIVNLSEYNKFMAIFLKRKVATANDLARLISIKVLSLNSVSKILGEESLLLMLDNSFYDHGMAFDLEKKHFTRRNLKTVFKALCDNLPTNYKRLLDLIAEYSPSKIVQDYAYKVIGSSEILGHKCLFSLASEMLSLGVVSTSSEYLLFEPNKDEREEDDGDMTEDEADVLDLYERLDFTNLWIFQLLTCHFLQKSETNNSAGYEQRCSRLVLDCIRISNNDILGSKLFDKVTDIEVLQNTLQVLEVSFLKNLLGHQIEGVSQYPLIVETIINISRKLNRVLAGNIALSKETSSLMQKCCQRFAMNDSEDLKALEPQLDVFLKILIVHQRFILKEGFENSTVLQKNDGNFLKLLCLLFQKIGFSLKLKLLLYDVLASLKSFALFSPSNGEQLLFRSARVKIPQELVDLPPFKISSFMTDTIKDDSKNIVELGIKDKEEVCHNYEPKFFFYNRKLERFEAELTLRPYHLLDNLQEDNEFNDTPLNLSLFNARFDRQNPT
Length1368
PositionKinase
OrganismLachancea dasiensis CBS 10888
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.10
Grand average of hydropathy-0.178
Instability index40.65
Isoelectric point6.33
Molecular weight158692.67
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10414
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     244.02|      74|     234|     659|     779|       1
---------------------------------------------------------------------------
  265-  301 (39.80/ 7.72)	..............................LVDF.VVKV....ENFE..CLPMTLHI.LI......VFWDGIFGSLPDSEN.........................................................
  550-  665 (49.79/69.04)	VKLSRLHQLLN..VFIGY.GIVKVPTYIRKLISSgVLYLtdsdDKFFhcELLINLKIsPLMK...................sqynmvlrnvvdvcpkyfedynydnlmallgeskdslltrnytffgsvpySVKLMTS
  697-  793 (102.76/88.84)	VNLKLYHQFYKwvEFIVYHKLLKDLEALECLVDI.LIYY....DRLF..SLLINDHI.LLMKtilhLYSDKLIWESPESQN.................................litlggflhffttrfpmALELDTD
  874-  923 (51.67/15.86)	VNLSEYNKFMA....IFLKRKVATANDLARLISIkVLSL....NSVS..KILGEESL.LLM.............................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     133.93|      41|      93|       3|      46|       2
---------------------------------------------------------------------------
    3-   38 (63.57/34.64)	......................................................NKYL.LNPPDNLHSLTADSRKRIYPDFDPWSHTPVQD
   39-  127 (46.27/28.34)	QIFLEfvskgyynsakvnfesissrsslqeslpavsehlaeqlskvmtireeqvNKIG.TNSPDSKSMHTAGS.DLCGPGFSLPKRVTLTD
  131-  152 (24.09/ 8.95)	ELWLQ.....................................................aLSSP...HSSLADTVKTI.P............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.95|      12|      99|     986|     998|       3
---------------------------------------------------------------------------
  986-  998 (17.48/19.14)	IGSSEILGHKcLF
 1088- 1099 (21.47/14.82)	ISNNDILGSK.LF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.19|      28|     233|     999|    1026|       4
---------------------------------------------------------------------------
  999- 1026 (45.52/26.26)	SLASEMLSLGVVSTSSEYLLFEPNKDER
 1234- 1261 (44.67/25.63)	SLKLKLLLYDVLASLKSFALFSPSNGEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.79|      16|     182|     216|     233|       8
---------------------------------------------------------------------------
  216-  233 (25.05/20.39)	LEKLvfEMTQYYNEPLKL
  403-  418 (27.73/15.50)	LKKL..ELIVYRNESLKF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10414 with Med12 domain of Kingdom Fungi
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